Pharmacology of Sympathomimetics
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Questions and Answers

What is a common adverse effect of selective β2 agonists?

  • Hypotension
  • Drowsiness
  • Tachycardia (correct)
  • Nausea
  • What action do β2 agonists primarily provide in the treatment of bronchial asthma?

  • Bronchodilation (correct)
  • Vasoconstriction
  • Diuresis
  • Sedation
  • What is the effect of ephedrine on CNS functioning?

  • Depression
  • Amnesia
  • Drowsiness
  • Euphoria (correct)
  • Which condition does ritodrine primarily treat?

    <p>Preterm labour</p> Signup and view all the answers

    What phenomenon is associated with the use of amphetamines?

    <p>Tolerance</p> Signup and view all the answers

    What is the main pharmacological action of mixed-acting sympathomimetics like ephedrine?

    <p>Slower actions with longer duration</p> Signup and view all the answers

    What adverse effect might a patient experience due to excessive use of ephedrine?

    <p>Urinary retention</p> Signup and view all the answers

    Which of the following is NOT a pharmacological action of β2 agonists?

    <p>Uterine contraction</p> Signup and view all the answers

    What type of receptors do sympathomimetic drugs primarily target?

    <p>Adrenergic receptors</p> Signup and view all the answers

    Which of the following statements is true regarding sympathomimetic drugs?

    <p>They are rapidly metabolized by COMT and MAO.</p> Signup and view all the answers

    What effect does epinephrine have on the cardiovascular system?

    <p>Increases force of cardiac contraction and heart rate</p> Signup and view all the answers

    Which adrenergic receptor is primarily responsible for vasoconstriction in skin and mucous membranes?

    <p>α1</p> Signup and view all the answers

    What effect does stimulation of β2 adrenergic receptors have in skeletal muscles?

    <p>Vasodilation of skeletal muscle blood vessels</p> Signup and view all the answers

    What is the primary effect of α2 adrenergic receptor stimulation?

    <p>Inhibition of norepinephrine release</p> Signup and view all the answers

    How does epinephrine affect diastolic blood pressure during α1 receptor stimulation?

    <p>May show slight increase or decrease</p> Signup and view all the answers

    What is the main difference between catecholamines and non-catecholamines?

    <p>Catecholamines are rapidly metabolized, non-catecholamines are not.</p> Signup and view all the answers

    What effect does β2 stimulation have on the diastolic blood pressure?

    <p>Decrease diastolic blood pressure</p> Signup and view all the answers

    Which of the following is NOT a pharmacological action of norepinephrine?

    <p>Stimulation of β2 adrenoceptors</p> Signup and view all the answers

    What is one therapeutic use of non-selective beta agonists like isoprenaline?

    <p>Bronchodilatation in bronchial asthma</p> Signup and view all the answers

    What adverse effect is commonly associated with the use of beta agonists?

    <p>Tachycardia</p> Signup and view all the answers

    Which agent is primarily used for treating hypotension by acting as an α1 selective agonist?

    <p>Midodrine</p> Signup and view all the answers

    How does β2 stimulation affect the urinary bladder?

    <p>Relaxes the bladder wall</p> Signup and view all the answers

    What is the primary purpose of using local anesthetic with a vasoconstrictor?

    <p>To delay absorption and prolong duration</p> Signup and view all the answers

    In the case of severe vasoconstriction and potential gangrene from extravasation, what is the advised treatment?

    <p>Intravenous phentolamine injection</p> Signup and view all the answers

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