Questions and Answers
What is the drug classification of Prozac?
What is the normal dose range for Prozac?
20-60 mg/day
What pharmacological action does Prozac perform?
Selectively inhibits reuptake of serotonin in CNS
Which of the following are therapeutic uses of Prozac? (Select all that apply)
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What are possible side effects of Prozac? (Select all that apply)
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Which substances can interact with Prozac?
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What should be monitored in patients taking Prozac? (Select all that apply)
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What are some nursing administration concerns for Prozac?
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What signifies the effectiveness of Prozac medication?
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Study Notes
Drug Classification
- Classified as a Selective Serotonin Reuptake Inhibitor (SSRI)
Dose Range
- Starting dose is typically 20 mg daily
- Maximum allowed dose is 80 mg daily
- Normal therapeutic dose range is between 20-60 mg daily
Pharmacological Action
- Functions by selectively inhibiting the reuptake of serotonin in the central nervous system (CNS)
Therapeutic Uses
- Prescribed for major depression
- Treats Obsessive-Compulsive Disorder (OCD)
- Effective for bulimia nervosa
- Used in managing panic disorder
- Addresses acute episodes of depression in individuals with bipolar disorder
Side Effects/Adverse Effects
- Risk of Neuroleptic Malignant Syndrome
- Possible seizures and suicidal thoughts
- Common side effects include drowsiness, headache, and dry eye
- Can cause menstrual irregularities and sexual dysfunction
- Weight fluctuations may occur; can lead to either weight loss or gain
- May result in tremors, hyponatremia, dehydration, and bleeding complications
Medications/Food Interactions
- Contraindicated with Monoamine Oxidase Inhibitors (MAOIs) and similar drugs
- Alcohol consumption may exacerbate side effects
- Interaction with CNS depressants is significant
- St. John's Wort can lead to serotonin syndrome when combined
- Grapefruit juice may alter drug metabolism
Nursing Interventions/Client Education
- Monitor for any signs of suicidal ideation
- Track changes in appetite, diet, and potential weight gain
- Observe for any sexual side effects
- Conduct Complete Blood Count (CBC) monitoring for leukopenia, anemia, and bleeding risk
- Ensure medication is taken as prescribed
- Advise against driving until personal response to medication is known
- Assess for use of OTC and herbal medications
- Recommend using sunscreen for skin protection
- Advise against breastfeeding or becoming pregnant during treatment
- Timing of administration should be aligned with side effects: AM for nervousness, PM for drowsiness
- Monitor for signs of hyponatremia and encourage adequate fluid intake
- Counsel on reporting any sexual difficulties to a healthcare provider
Nursing Administration Concerns
- History of using MAOIs should be reviewed
- Caution with patients having a history of seizures or myocardial infarction (MI)
- Take precautions with dehydrated individuals and those breastfeeding
- Consider renal or hepatic impairment before prescribing
- Monitor those with seizure disorders, diabetes mellitus, or increased intraocular pressure (glaucoma)
- Be mindful of hypokalemia, hypomagnesemia, and uncompensated heart failure
- Consider possible effects on bradycardia and evaluate in obstetric, pediatric, geriatric, and underweight adult populations
Evaluation of Medication Effectiveness
- Improvement may be indicated by an increased sense of well-being
- Renewed interest in activities and surroundings is a positive sign
- Decreased frequency of panic attacks suggests effectiveness
- Reduction in mood fluctuations is also a key indicator of therapeutic success
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Description
This quiz covers the classification, dosage, pharmacological action, therapeutic uses, and side effects of Selective Serotonin Reuptake Inhibitors (SSRIs). Test your knowledge of how these medications work in the treatment of various mental health disorders, including their benefits and risks. Perfect for students studying pharmacology or healthcare professionals looking to refresh their knowledge.
