Pharmacology of Smooth Muscles and Histamine
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Questions and Answers

Smooth muscles are responsible for the contraction of smooth muscle tissue.

True

Capillaries exclusively cause constriction and do not affect plasma permeability.

False

The primary function of smooth muscles is to facilitate relaxation of tissues.

False

Dilation of capillaries leads to a decrease in their permeability to plasma.

<p>False</p> Signup and view all the answers

Smooth muscle contraction is not involved in the functioning of capillaries.

<p>True</p> Signup and view all the answers

Histamine is released from mast cells and causes a tertiary response.

<p>True</p> Signup and view all the answers

External histamine comes from injections and causes a weaker response.

<p>False</p> Signup and view all the answers

Adrenaline acts as a vasoconstrictor and increases capillary permeability.

<p>False</p> Signup and view all the answers

Alpha-agonists like adrenaline have an effect on blood vessel constriction.

<p>True</p> Signup and view all the answers

Mast cells are responsible for the release of adrenaline in the body.

<p>False</p> Signup and view all the answers

Mast cell destruction leads to the release of histamine.

<p>True</p> Signup and view all the answers

Histamine release causes vasoconstriction of blood vessels.

<p>False</p> Signup and view all the answers

Vasodilatation at the site of injection is a direct action of histamine.

<p>True</p> Signup and view all the answers

Destruction of epidermal cells is a result of histamine release.

<p>False</p> Signup and view all the answers

The site of injection experiences increased blood flow due to histamine's effects.

<p>True</p> Signup and view all the answers

Antihistamines block H2 receptors to reduce redness.

<p>False</p> Signup and view all the answers

The primary role of antihistamines is to act as antagonists for histamine.

<p>True</p> Signup and view all the answers

Areas of reduced blood flow can be observed after antihistamine administration due to H1 receptor blockage.

<p>False</p> Signup and view all the answers

Antihistamines only minimize the effects of histamine related to capillary permeability.

<p>False</p> Signup and view all the answers

Histamine contributes to the dilation of blood vessels when H1 receptors are activated.

<p>True</p> Signup and view all the answers

H1 receptors are found in blood vessels of the skin, bronchi, and intestine.

<p>True</p> Signup and view all the answers

H2 receptors are exclusively located in the blood vessels of the skin.

<p>False</p> Signup and view all the answers

Antihistamines block H1 receptors only.

<p>True</p> Signup and view all the answers

H2 receptors play a role in the constriction of arterioles.

<p>True</p> Signup and view all the answers

Only H1 receptors affect the permeability of capillaries.

<p>False</p> Signup and view all the answers

Study Notes

Smooth Muscles

  • Cause contraction

Capillaries

  • Cause dilation
  • Increased permeability to plasma

Mast Cell Destruction

  • Releases histamine from the epidermis
  • Causes vasodilation of blood vessels at the site of injection

Adrenaline

  • Vasoconstrictor α- agonist
  • Reduces capillaries permeability

Histamine and Antihistamines

  • Antihistamines are pharmacological antagonists of histamine
  • Antihistamines block only H1 receptors, not H2 receptors
  • H1 receptors are found in blood vessels of the skin, bronchi, and intestines.
  • H2 receptors are found in arterioles, capillaries, and parietal cells.

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Description

This quiz covers the roles of smooth muscles, capillaries, and the mechanisms of mast cell destruction in relation to histamine and antihistamines. It explores concepts such as vasodilation and vasoconstriction, focusing on the pharmacological effects of these substances on blood vessels. Test your understanding of how these interactions affect circulation and tissue response.

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