Pharmacology of Sedative-Hypnotic Drugs in Dental Management

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Which of the following is NOT a type of sedative-hypnotic drug?

Barbiturates

Buspirone

Benzodiazepines

Anti-depressants (correct)

What is the common desired therapeutic response to sedative-hypnotic drugs in dentistry?

Sedation or hypnosis (correct)

Pain relief

Muscle relaxation

Anesthesia

What is the primary function of hypnotic drugs?

To initiate or sustain anesthesia

To calm or relieve anxiety

To induce sleep and treat insomnia (correct)

To treat mild neurosis

What is the mechanism of action of Benzodiazepines?

Acting on GABAA receptors Signup and view all the answers

Sedative-hypnotic drugs are often used in dentistry for the premedication of:

Patients with dental anxiety and mild neurosis Signup and view all the answers

What is the term that describes drugs that serve to calm or relieve anxiety?

Sedative Signup and view all the answers

What is a major reason why benzodiazepines are preferred over barbiturates in routine medical practice?

Benzodiazepines are less dangerous in overdose Signup and view all the answers

What is the effect of benzodiazepines on GABA?

It increases the inhibitory effects of GABA Signup and view all the answers

What is a common problem associated with long-term use of barbiturates?

Tolerance and drug interactions Signup and view all the answers

Which of the following is a contraindication for the use of barbiturates?

Pregnancy, especially during the first trimester Signup and view all the answers

What is the recommended duration of benzodiazepine treatment for insomnia?

Up to 2 to 4 weeks Signup and view all the answers

What is triazolam recommended for due to its short half-life and rapid onset?

Pre-operative sedative Signup and view all the answers

What is a use of barbiturates that has not been largely replaced by benzodiazepines?

General anesthesia Signup and view all the answers

What is a characteristic of longer-acting benzodiazepines like nitrazepam and diazepam?

They have residual effects that may persist into the next day Signup and view all the answers

What is a potential drawback of benzodiazepines?

All of the above Signup and view all the answers

What is the use of intravenous diazepam in surgical procedures?

For the relief of intraoperative anxiety Signup and view all the answers

What is an advantage of using barbiturates in dentistry?

They are less expensive and effective Signup and view all the answers

What is the effect of benzodiazepines on anxiety?

It decreases anxiety Signup and view all the answers

What is the primary purpose of using intravenous diazepam in patients undergoing surgical removal of impacted third molars?

To relieve intraoperative anxiety Signup and view all the answers

What is a potential adverse reaction associated with long-term use of benzodiazepines such as diazepam?

All of the above Signup and view all the answers

What is the effect of alcohol on benzodiazepines like diazepam?

Alcohol enhances the rate of absorption and CNS depression Signup and view all the answers

What is the mechanism of action of phenoparbital, a type of barbiturate?

By binding to a site on the GABAA receptor/chloride channel Signup and view all the answers

What is a therapeutic use of barbiturates in dentistry?

Occasionally being helpful in dentistry Signup and view all the answers

What is a potential adverse reaction associated with the use of barbiturates?

Significant depression of the CNS Signup and view all the answers

What is the consequence of combining antianxiety agents with other CNS depressants?

Increased risk of CNS depression Signup and view all the answers

Which of the following substances can increase the CNS depressant effects of benzodiazepines?

Alcohol Signup and view all the answers

What is the mechanism of action of benzodiazepines?

Increasing the inhibitory effects of GABA Signup and view all the answers

What is the therapeutic use of flumazenil in dentistry?

To reverse benzodiazepine-induced sedation Signup and view all the answers

Which of the following is NOT a therapeutic use of benzodiazepines in dentistry?

Antidepressant Signup and view all the answers

What is the generic name of the benzodiazepine used for the relief of intraoperative anxiety?

Diazepam Signup and view all the answers