28 Questions
What is the function of GnRH produced by the Hypothalamus?
To stimulate the Anterior Pituitary
Which of the following is a GnRH Antagonist drug?
Degarelix
What is the effect of estrogen on endometrium?
It drives the growth of endometrium
Which of the following is a SERM?
Raloxifene
What is the use of HPG Axis drugs in Hormone Replacement Therapy?
To prevent osteoporosis post menopause
Which of the following is a Progestin?
Levonorgestrel
What is the result of disruption of HPG Axis in females?
All of the above
What is the use of HPG Axis drugs in treatment of Benign Prostatic Hyperplasia (BPH)?
To inhibit testosterone production
Which of the following is a Testosterone Agonist?
Methyltestosterone
What is the initial effect of GnRH on LH and FSH levels?
Increase
What is the long-term effect of continuous GnRH administration on LH and FSH levels?
Decrease
What is the role of testosterone in its own production?
Negative feedback
What is the effect of estrogen on its own production?
Either negative or positive feedback
What is the effect of progesterone on its own production?
Negative feedback
What is the purpose of GnRH analogs in prostate carcinoma treatment?
To decrease testosterone levels
What is the purpose of GnRH antagonists in ovulation induction?
To inhibit FSH and LH release
What is a common side effect of long-term GnRH analog use?
Osteoporosis
What is the purpose of GnRH antagonists in endometriosis treatment?
To inhibit estrogen release
What is the type of hormones that LH, FSH, and hCG belong to?
Glycopeptide hormones
Which of the following is NOT a site of synthesis for gonadotropins?
Posterior pituitary
What is the function of hCG in infertility treatment?
To trigger ovulation
What is the goal of controlled ovarian stimulation?
To harvest multiple oocytes
What is menotropin derived from?
Urine of menopausal women
What is the side effect of ovarian hyperstimulation syndrome (OHSS)?
Excessive stimulation of the ovaries
What is the function of GnRH agonist and antagonist in fertility treatment?
To suppress endogenous cycle
What is the function of follitropin in fertility treatment?
To stimulate follicular development
What is the purpose of hormone replacement therapy in fertility treatment?
To stimulate growth and development of ovarian follicles
What is lutropin?
Recombinant LH
Test your knowledge of the Hypothalamic-Pituitary-Gonadal (HPG) Axis, including hormone agonists and antagonists, and their effects on the reproductive system. Learn about GnRH, FSH, LH, testosterone, and estrogen, and how they regulate secondary sex characteristics, spermatogenesis, and folliculogenesis.
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