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Questions and Answers
What is the primary mechanism by which opioids exert their analgesic effects?
What is the primary mechanism by which opioids exert their analgesic effects?
- By activating opioid receptors and inhibiting neurotransmitter release (correct)
- By directly damaging peripheral tissues
- By blocking the release of neurotransmitters
- By stimulating the release of substance P
What is the main site of extensive metabolism for opioids?
What is the main site of extensive metabolism for opioids?
- Kidney
- Liver (correct)
- Lungs
- Brain
What is the range of elimination half-life of opioids depending on the specific drug and route of administration?
What is the range of elimination half-life of opioids depending on the specific drug and route of administration?
- Hours to days
- Hours to weeks
- Minutes to hours (correct)
- Days to weeks
What is the name of the receptors that opioids bind to in order to exert their analgesic effects?
What is the name of the receptors that opioids bind to in order to exert their analgesic effects?
What is the effect of opioid activation on neuronal excitability?
What is the effect of opioid activation on neuronal excitability?
Which of the following opioids is a pure antagonist?
Which of the following opioids is a pure antagonist?
What is a common adverse effect of opioids that can be life-threatening in cases of overdose or misuse?
What is a common adverse effect of opioids that can be life-threatening in cases of overdose or misuse?
What is a consequence of prolonged use of opioids?
What is a consequence of prolonged use of opioids?
Which of the following is a guideline for the use of opioids?
Which of the following is a guideline for the use of opioids?
What is a potential drug interaction with opioids?
What is a potential drug interaction with opioids?
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