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Pharmacology of Narcotic Analgesics
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Pharmacology of Narcotic Analgesics

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Questions and Answers

What is the primary mechanism by which opioids exert their analgesic effects?

  • By activating opioid receptors and inhibiting neurotransmitter release (correct)
  • By directly damaging peripheral tissues
  • By blocking the release of neurotransmitters
  • By stimulating the release of substance P
  • What is the main site of extensive metabolism for opioids?

  • Kidney
  • Liver (correct)
  • Lungs
  • Brain
  • What is the range of elimination half-life of opioids depending on the specific drug and route of administration?

  • Hours to days
  • Hours to weeks
  • Minutes to hours (correct)
  • Days to weeks
  • What is the name of the receptors that opioids bind to in order to exert their analgesic effects?

    <p>Opioid receptors</p> Signup and view all the answers

    What is the effect of opioid activation on neuronal excitability?

    <p>It modulates neuronal excitability</p> Signup and view all the answers

    Which of the following opioids is a pure antagonist?

    <p>Naloxone</p> Signup and view all the answers

    What is a common adverse effect of opioids that can be life-threatening in cases of overdose or misuse?

    <p>Respiratory depression</p> Signup and view all the answers

    What is a consequence of prolonged use of opioids?

    <p>Tolerance and physical dependence</p> Signup and view all the answers

    Which of the following is a guideline for the use of opioids?

    <p>Prescribe opioids judiciously and use them as part of a comprehensive pain management plan</p> Signup and view all the answers

    What is a potential drug interaction with opioids?

    <p>Benzodiazepines</p> Signup and view all the answers

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