Pharmacology of Cholinergic Receptors
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Questions and Answers

Which drug stimulates M- and H-cholinergic receptors?

  • Galantamine hydrobromide
  • Prozerin
  • Carbacholine (correct)
  • Pilocarpine

    • What is the effect of acetylcholine on sweat glands?

  • Increased secretion of sweat glands (correct)
  • Paralysis of accommodation
  • Mydriasis
  • Tachycardia

    • Which anticholinesterase drug is used for glaucoma?

  • Pilocarpine (correct)
  • Galantamine
  • Edrophonium
  • Physostigmine

    • What is characteristic of carbacholin?

    <p>Used for glaucoma</p> Signup and view all the answers

    Which anticholinesterase agent is used as an antidepolarizing antagonist muscle relaxant?

    <p>Edrophonium</p> Signup and view all the answers

    What symptom is observed under the influence of anticholinesterase drugs?

    <p>Decrease in intraocular pressure</p> Signup and view all the answers

    Which drug is an anticholinesterase agent?

    <p>Aceclidine</p> Signup and view all the answers

    What is the effect of carbacholine on intraocular pressure?

    <p>Decrease</p> Signup and view all the answers

    What effect does stimulation of beta-1 adrenergic receptors of the heart have?

    <p>increased strength of heart contractions</p> Signup and view all the answers

    Which of the following is an adrenergic agonist?

    <p>terbutaline</p> Signup and view all the answers

    What is the effect of labetalol on the heart?

    <p>difficulty in atrioventricular conduction</p> Signup and view all the answers

    Which of the following is NOT an adrenergic agonist?

    <p>atropine</p> Signup and view all the answers

    What is the effect of reserpine on the heart?

    <p>decrease in automaticity</p> Signup and view all the answers

    Which of the following is a sympathomimetic?

    <p>ephedrine</p> Signup and view all the answers

    What is the effect of stimulation of beta-1 adrenergic receptors on atrioventricular conduction?

    <p>difficulty in atrioventricular conduction</p> Signup and view all the answers

    Which of the following stimulates alpha and beta adrenergic receptors?

    <p>adrenalin</p> Signup and view all the answers

    Which anesthetic is characterized by increased spinal reflexes?

    <p>Propanidid</p> Signup and view all the answers

    What is the effect of anesthesia in the agonal stage?

    <p>Pupils are sharply dilated, breathing rate increases</p> Signup and view all the answers

    What is the characteristic of Propofol?

    <p>A/D rises sharply</p> Signup and view all the answers

    Which anesthetic is used as a sedative?

    <p>Anesthesin</p> Signup and view all the answers

    What is the duration of anesthesia of Propanidide?

    <p>5 minutes</p> Signup and view all the answers

    Which anesthetic is administered by inhalation?

    <p>Propanidide</p> Signup and view all the answers

    What is the characteristic of Thiopental - sodium?

    <p>Pronounced stage of excitation</p> Signup and view all the answers

    Which anesthetic is used for hypertonic disease?

    <p>Trimecaine</p> Signup and view all the answers

    Which of the following is an alpha- and beta- adrenergic receptor blocker?

    <p>labetalol</p> Signup and view all the answers

    Which of the following is used to treat bronchospasm?

    <p>salbutamol</p> Signup and view all the answers

    What is the effect of adrenaline on the heart?

    <p>increases the strength of heart contractions</p> Signup and view all the answers

    Which of the following is an alpha- adrenergic agonist used only locally for rhinitis?

    <p>galazolin</p> Signup and view all the answers

    What is the indication for the use of isadrin?

    <p>rhinitis</p> Signup and view all the answers

    Which of the following is a sympatholytic?

    <p>ornid</p> Signup and view all the answers

    What is diazepam (sibazon) indicated for?

    <p>Neuroses</p> Signup and view all the answers

    What is the purpose of administering naloxone?

    <p>Reversal of opioid overdose</p> Signup and view all the answers

    Which of the following is an adrenergic agonist with a predominant effect on beta-2 adrenergic receptors?

    <p>salbutamol</p> Signup and view all the answers

    Which of the following is a psychostimulant?

    <p>Sydnocarb</p> Signup and view all the answers

    Which of the following is an alpha- adrenergic receptor blocker?

    <p>prazosin</p> Signup and view all the answers

    What is the property of Imizin?

    <p>Antidepressant</p> Signup and view all the answers

    What is the indication for the use of chlorprothixene?

    <p>Psychoses</p> Signup and view all the answers

    What is the purpose of administering sodium chloride?

    <p>Treatment of bromism</p> Signup and view all the answers

    What is the property of Phenamine?

    <p>Psychostimulant</p> Signup and view all the answers

    What is the purpose of administering caffeine?

    <p>Treatment of narcolepsy</p> Signup and view all the answers

    Study Notes

    Cholinergic Receptors

    • M- and H- cholinergic receptors are stimulated by pilocarpine, aceclidine, and carbacholine.
    • Prozerin is an anticholinesterase drug used for glaucoma.

    Effects of Acetylcholine

    • Increased secretion of sweat glands occurs under the influence of acetylcholine.
    • Mydriasis, increased intraocular pressure, paralysis of accommodation, and tachycardia are effects of acetylcholine.

    Anticholinesterase Agents

    • Physostigmine and galantamine are anticholinesterase agents.
    • Edrophonium is an anticholinesterase agent used as an antidepolarizing antagonist muscle relaxant.

    Cholinomimetic Agents

    • Carbacholine is used for glaucoma and blocks M- cholinergic receptors.
    • Aceclidine is a cholinomimetic agent that blocks H- cholinergic receptors.

    Adrenergic Receptors

    • Beta-1 adrenergic receptors of the heart are stimulated, leading to increased strength of heart contractions, decreased heart rate, and difficulty in atrioventricular conduction.

    Adrenergic Agonists

    • Adrenalin stimulates alpha and beta adrenergic receptors.
    • Terbutaline, dobutamine, and norepinephrine are adrenergic agonists.
    • Ephedrine is a sympathomimetic that stimulates alpha and beta adrenergic receptors.

    Alpha- and Beta-Adrenergic Receptor Blockers

    • Labetalol and carvedilol are alpha- and beta-adrenergic receptor blockers.

    Anesthetics

    • Propofol, anesthesin, morphine, and trimecaine are anesthetics.
    • Thiopental-sodium is a short-acting anesthetic.
    • Hexenal is an anesthetic administered by inhalation.

    Psychostimulants

    • Pyridrol, codeine, bemegrid, piracetam, and amitriptyline are psychostimulants.
    • Sydnocarb is a psychostimulant from the sydnonimine group.

    Antidepressants

    • Amitriptyline, diazepam (sibazon), phenazepam, and phenamine are antidepressants.
    • Nialamide and imizin are antidepressant monoamine oxidase inhibitors.

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    Description

    This quiz assesses knowledge of cholinergic receptors and related pharmacological agents. Topics include M- and H-receptors and specific drugs that stimulate or inhibit them.

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