Pharmacology of Cholinergic Receptors

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40 Questions

Which drug stimulates M- and H-cholinergic receptors?

Carbacholine

What is the effect of acetylcholine on sweat glands?

Increased secretion of sweat glands

Which anticholinesterase drug is used for glaucoma?

Pilocarpine

What is characteristic of carbacholin?

Used for glaucoma

Which anticholinesterase agent is used as an antidepolarizing antagonist muscle relaxant?

Edrophonium

What symptom is observed under the influence of anticholinesterase drugs?

Decrease in intraocular pressure

Which drug is an anticholinesterase agent?

Aceclidine

What is the effect of carbacholine on intraocular pressure?

Decrease

What effect does stimulation of beta-1 adrenergic receptors of the heart have?

increased strength of heart contractions

Which of the following is an adrenergic agonist?

terbutaline

What is the effect of labetalol on the heart?

difficulty in atrioventricular conduction

Which of the following is NOT an adrenergic agonist?

atropine

What is the effect of reserpine on the heart?

decrease in automaticity

Which of the following is a sympathomimetic?

ephedrine

What is the effect of stimulation of beta-1 adrenergic receptors on atrioventricular conduction?

difficulty in atrioventricular conduction

Which of the following stimulates alpha and beta adrenergic receptors?

adrenalin

Which anesthetic is characterized by increased spinal reflexes?

Propanidid

What is the effect of anesthesia in the agonal stage?

Pupils are sharply dilated, breathing rate increases

What is the characteristic of Propofol?

A/D rises sharply

Which anesthetic is used as a sedative?

Anesthesin

What is the duration of anesthesia of Propanidide?

5 minutes

Which anesthetic is administered by inhalation?

Propanidide

What is the characteristic of Thiopental - sodium?

Pronounced stage of excitation

Which anesthetic is used for hypertonic disease?

Trimecaine

Which of the following is an alpha- and beta- adrenergic receptor blocker?

labetalol

Which of the following is used to treat bronchospasm?

salbutamol

What is the effect of adrenaline on the heart?

increases the strength of heart contractions

Which of the following is an alpha- adrenergic agonist used only locally for rhinitis?

galazolin

What is the indication for the use of isadrin?

rhinitis

Which of the following is a sympatholytic?

ornid

What is diazepam (sibazon) indicated for?

Neuroses

What is the purpose of administering naloxone?

Reversal of opioid overdose

Which of the following is an adrenergic agonist with a predominant effect on beta-2 adrenergic receptors?

salbutamol

Which of the following is a psychostimulant?

Sydnocarb

Which of the following is an alpha- adrenergic receptor blocker?

prazosin

What is the property of Imizin?

Antidepressant

What is the indication for the use of chlorprothixene?

Psychoses

What is the purpose of administering sodium chloride?

Treatment of bromism

What is the property of Phenamine?

Psychostimulant

What is the purpose of administering caffeine?

Treatment of narcolepsy

Study Notes

Cholinergic Receptors

  • M- and H- cholinergic receptors are stimulated by pilocarpine, aceclidine, and carbacholine.
  • Prozerin is an anticholinesterase drug used for glaucoma.

Effects of Acetylcholine

  • Increased secretion of sweat glands occurs under the influence of acetylcholine.
  • Mydriasis, increased intraocular pressure, paralysis of accommodation, and tachycardia are effects of acetylcholine.

Anticholinesterase Agents

  • Physostigmine and galantamine are anticholinesterase agents.
  • Edrophonium is an anticholinesterase agent used as an antidepolarizing antagonist muscle relaxant.

Cholinomimetic Agents

  • Carbacholine is used for glaucoma and blocks M- cholinergic receptors.
  • Aceclidine is a cholinomimetic agent that blocks H- cholinergic receptors.

Adrenergic Receptors

  • Beta-1 adrenergic receptors of the heart are stimulated, leading to increased strength of heart contractions, decreased heart rate, and difficulty in atrioventricular conduction.

Adrenergic Agonists

  • Adrenalin stimulates alpha and beta adrenergic receptors.
  • Terbutaline, dobutamine, and norepinephrine are adrenergic agonists.
  • Ephedrine is a sympathomimetic that stimulates alpha and beta adrenergic receptors.

Alpha- and Beta-Adrenergic Receptor Blockers

  • Labetalol and carvedilol are alpha- and beta-adrenergic receptor blockers.

Anesthetics

  • Propofol, anesthesin, morphine, and trimecaine are anesthetics.
  • Thiopental-sodium is a short-acting anesthetic.
  • Hexenal is an anesthetic administered by inhalation.

Psychostimulants

  • Pyridrol, codeine, bemegrid, piracetam, and amitriptyline are psychostimulants.
  • Sydnocarb is a psychostimulant from the sydnonimine group.

Antidepressants

  • Amitriptyline, diazepam (sibazon), phenazepam, and phenamine are antidepressants.
  • Nialamide and imizin are antidepressant monoamine oxidase inhibitors.

This quiz assesses knowledge of cholinergic receptors and related pharmacological agents. Topics include M- and H-receptors and specific drugs that stimulate or inhibit them.

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