Pharmacology of Beta Blockers
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Questions and Answers

What is the result of blocking the sympathetic nervous system stimulation on hepatic glucose production?

  • Variable effect on glucose production
  • No effect on glucose production
  • Increased glucose production
  • Decreased glucose production (correct)
  • Which of the following beta blockers is more likely to cause hypoglycemia?

  • Metoprolol
  • Esmolol
  • Atenolol
  • Propranolol (correct)
  • What is the effect of beta blockers on bronchospasm in patients with asthma or COPD?

  • Variable effect on bronchospasm
  • Relief of bronchospasm
  • No effect on bronchospasm
  • Exacerbation of bronchospasm (correct)
  • Which of the following beta blockers is the most selective for the beta-1 receptor?

    <p>Atenolol</p> Signup and view all the answers

    What is the effect of propranolol on infantile hemangioma cell growth?

    <p>Represses cell growth</p> Signup and view all the answers

    What is the consequence of sudden withdrawal of beta blockers?

    <p>Increased catecholamine sensitivity</p> Signup and view all the answers

    What is the effect of an alpha 1 agonist on vasoconstriction?

    <p>Increase vasoconstriction</p> Signup and view all the answers

    What is the mechanism of action of prazosin in relation to alpha 1 receptors?

    <p>Acts as an inverse agonist at the A1 adrenergic receptor</p> Signup and view all the answers

    Why is phentolamine contraindicated in patients with hypotension and bradycardia?

    <p>It can cause reflex bradycardia</p> Signup and view all the answers

    What is the primary effect of alpha 2 antagonists on norepinephrine release?

    <p>Increase norepinephrine release</p> Signup and view all the answers

    What is the primary indication for phentolamine?

    <p>Pheochromocytoma</p> Signup and view all the answers

    What is the effect of alpha 1 blockade on peripheral resistance?

    <p>Decrease peripheral resistance</p> Signup and view all the answers

    Which of the following alpha1-adrenergic blockers is specifically used to treat BPH?

    <p>Tamsulosin</p> Signup and view all the answers

    What is the main concern when administering alpha1 blockers to patients with renal failure?

    <p>Increased drug sensitivity</p> Signup and view all the answers

    Which of the following beta blockers has both non-selective beta receptor antagonist and alpha receptor antagonist properties?

    <p>Labetalol</p> Signup and view all the answers

    What is the primary indication for the use of Prazosin?

    <p>Hypertension and BPH</p> Signup and view all the answers

    What is the volume of distribution of Prazosin?

    <p>0.6 L/kg</p> Signup and view all the answers

    Which of the following is a common side effect of Prazosin?

    <p>All of the above</p> Signup and view all the answers

    What is the half-life of Propranolol?

    <p>3.9-6.4 hours</p> Signup and view all the answers

    When is IV use of Propranolol indicated?

    <p>For the management of life-threatening arrhythmias</p> Signup and view all the answers

    What is the sequence of treatment for pheochromocytoma?

    <p>PO alpha blockade followed by PO beta blockade</p> Signup and view all the answers

    Which of the following beta blockers is very lipid soluble and can cross the BBB?

    <p>Propranolol</p> Signup and view all the answers

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