Pharmacology Interactions and Treatments

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Questions and Answers

What is a potential side effect of mucolytic agents such as hypertonic saline solution or acetylcysteine?

  • Bronchospasm (correct)
  • Fluid overload
  • Increased mucus production
  • Electrolyte imbalance

What should a nurse advise a client regarding the use of a short-acting beta-2 agonist (SABA)?

  • Use the SABA as the primary treatment for asthma control.
  • Take the SABA with an oral glucocorticoid for effectiveness.
  • Notify the provider if the SABA is needed more than twice per week. (correct)
  • SABAs provide prolonged control of asthma.

What describes the primary mechanism of action of omalizumab?

  • It reduces the number of immunoglobulin E (IgE) molecules on mast cells. (correct)
  • It decreases the synthesis of inflammatory mediators.
  • It stabilizes mast cell membranes.
  • It relaxes smooth muscles by blocking adenosine receptors.

Which of the following is true regarding short-acting beta-2 agonists (SABAs)?

<p>They should not be used more than twice per week. (D)</p> Signup and view all the answers

Which incorrect statement might a patient make regarding mucolytic agents?

<p>These agents can provide great fluid overload. (B)</p> Signup and view all the answers

What should not be expected from a short-acting beta-2 agonist (SABA)?

<p>Long-lasting control of asthma attacks (A)</p> Signup and view all the answers

What is a potential consequence of combining zafirlukast with theophylline?

<p>Suppressed metabolism of theophylline (A)</p> Signup and view all the answers

Which is an effect of using SABA too frequently?

<p>Serious adverse effects (D)</p> Signup and view all the answers

Which statement indicates a client understands the dietary needs while taking hydrochlorothiazide?

<p>This medication can cause a loss of potassium. (D)</p> Signup and view all the answers

Why should a client report increased SABA use to their provider?

<p>They may need additional medication. (B)</p> Signup and view all the answers

Which of the following is NOT an interaction to consider with the use of theophylline?

<p>Zafirlukast (A)</p> Signup and view all the answers

What adverse effect should a nurse monitor for in a client prescribed a mucolytic agent?

<p>Bronchospasm (C)</p> Signup and view all the answers

Why should a client taking hydrochlorothiazide consume potassium-rich foods?

<p>To avoid hypokalemia (C)</p> Signup and view all the answers

What is the primary role of albuterol sulfate in treatment?

<p>To treat acute bronchospasm (C)</p> Signup and view all the answers

What is a key reason for prescribing enteric-coated aspirin for stroke prophylaxis?

<p>Enteric-coated medications cause less gastric irritation. (D)</p> Signup and view all the answers

Which of these medications is correctly paired with its classification?

<p>Cromolyn - mast cell stabilizer (C)</p> Signup and view all the answers

What is a common misconception about the effect of potassium when taking hydrochlorothiazide?

<p>Potassium affects the medication’s effectiveness. (C)</p> Signup and view all the answers

Why might long-term treatment with glucocorticoids lead to hypertension?

<p>Due to sodium and water retention. (B)</p> Signup and view all the answers

Which medication should a nurse anticipate for a client with atrial fibrillation scheduled for cardioversion?

<p>Diltiazem (A)</p> Signup and view all the answers

What side effects might a nurse expect from long-term glucocorticoid treatment?

<p>Restlessness and agitation. (A)</p> Signup and view all the answers

Which of the following statements about enteric-coated medications is incorrect?

<p>They enhance gastric absorption of medications. (B)</p> Signup and view all the answers

Which medication is NOT typically used to treat arrhythmias?

<p>Amlodipine (C)</p> Signup and view all the answers

What happens if the coating of an enteric-coated medication fails to dissolve?

<p>No absorption of the medication will occur. (B)</p> Signup and view all the answers

Which of the following statements about diltiazem is true?

<p>It is a calcium channel blocker that lowers blood pressure. (C)</p> Signup and view all the answers

What adverse effect should a nurse monitor for when administering subcutaneous epinephrine?

<p>Tachycardia (D)</p> Signup and view all the answers

What is a possible serious adverse effect of alteplase administration?

<p>Bleeding (D)</p> Signup and view all the answers

Which client statement indicates understanding of the nitroglycerin patch application?

<p>I can place the patch on any area of my body without hair. (D)</p> Signup and view all the answers

Which symptom is NOT an expected adverse effect of epinephrine?

<p>Hyperthermia (C)</p> Signup and view all the answers

Why is bleeding a concern when administering alteplase?

<p>It can catalyze the conversion of plasminogen to plasmin. (A)</p> Signup and view all the answers

Which of the following is an incorrect practice regarding the nitroglycerin patch?

<p>Applying it over a hairy area. (B)</p> Signup and view all the answers

What is a major action of epinephrine that might cause tachycardia?

<p>Activation of beta-adrenergic receptors. (D)</p> Signup and view all the answers

Which statement about alteplase is true?

<p>It is a thrombolytic agent that dissolves clots. (B)</p> Signup and view all the answers

Why should the nitroglycerin transdermal patch be applied to hairless skin?

<p>Hair creates a physical barrier to absorption. (C)</p> Signup and view all the answers

Which statement about the nitroglycerin patch placement is correct?

<p>It should not be placed on the same site as a previous patch. (D)</p> Signup and view all the answers

What is an expected side effect of brompheniramine?

<p>Dry mouth. (C)</p> Signup and view all the answers

What advice should the nurse give to alleviate dry mouth caused by brompheniramine?

<p>Suck on hard, sugarless candy or take frequent sips of liquid. (C)</p> Signup and view all the answers

What central nervous system effects might a client experience while taking brompheniramine?

<p>Dizziness and confusion. (C)</p> Signup and view all the answers

What medication is typically prescribed for a client experiencing unstable angina?

<p>Nitroglycerin (D)</p> Signup and view all the answers

Which of the following gastrointestinal disturbances is known and does not need immediate reporting for a client taking brompheniramine?

<p>Nausea and vomiting. (B), Constipation. (C), Loss of appetite. (D)</p> Signup and view all the answers

What is a potential side effect related to urinary frequency when taking brompheniramine?

<p>Increased urinary frequency. (A)</p> Signup and view all the answers

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Study Notes

Theophylline Interactions

  • Zafirlukast suppresses the metabolism of theophylline, leading to potential toxicity.
  • Theophylline should not be used with zafirlukast.

Hydrochlorothiazide

  • Decreases potassium levels in the body.
  • Requires a potassium-rich diet to avoid hypokalemia.
  • Foods rich in potassium include: bananas, raisins, baked potatoes, pumpkins, and milk.

Mucolytics

  • Thin mucus secretions.
  • Can irritate airways, causing bronchospasm.
  • Adverse effects can include a cough and thinning mucus secretions.

Short-Acting Beta-2 Agonists (SABAs)

  • Used for the treatment of asthma attacks.
  • Not for long-term asthma control.
  • If used more than twice a week, a long-acting beta-2 agonist (LABA) should be considered.

Omalizumab

  • Reduces the number of immunoglobulin E (IgE) molecules on mast cells.
  • Reduces allergic response.

Glucocorticoids

  • Long-term use can cause hypertension.
  • Can cause restlessness, agitation, anxiety, and irritability.

Enteric-Coated Aspirin

  • Dissolves in the small intestine, reducing gastric irritation.
  • Protects the stomach lining from the effects of aspirin.

Diltiazem

  • Calcium channel blocker.
  • Reduces blood pressure.
  • Used during cardioversion to treat atrial fibrillation.

Epinephrine

  • Adrenergic agonist.
  • Can cause tachycardia and dysrhythmia stimulation.

Alteplase

  • Thrombolytic medication used to dissolve clots.
  • Can cause bleeding.

Nitroglycerin Patch

  • Should be applied to hairless skin for optimal absorption.
  • Can cause skin irritation if applied to the same site repeatedly.

Brompheniramine

  • First-generation antihistamine.
  • Dry mouth can be an expected effect.
  • Can cause gastrointestinal disturbances (nausea, vomiting, loss of appetite, diarrhea, constipation).
  • Can cause central nervous system effects (dizziness, poor coordination, confusion, fatigue) .

Unstable Angina

  • Nitroglycerin is the medication of choice to treat unstable angina.

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