Pharmacology Interactions and Treatments
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Questions and Answers

What is a potential side effect of mucolytic agents such as hypertonic saline solution or acetylcysteine?

  • Bronchospasm (correct)
  • Fluid overload
  • Increased mucus production
  • Electrolyte imbalance
  • What should a nurse advise a client regarding the use of a short-acting beta-2 agonist (SABA)?

  • Use the SABA as the primary treatment for asthma control.
  • Take the SABA with an oral glucocorticoid for effectiveness.
  • Notify the provider if the SABA is needed more than twice per week. (correct)
  • SABAs provide prolonged control of asthma.
  • What describes the primary mechanism of action of omalizumab?

  • It reduces the number of immunoglobulin E (IgE) molecules on mast cells. (correct)
  • It decreases the synthesis of inflammatory mediators.
  • It stabilizes mast cell membranes.
  • It relaxes smooth muscles by blocking adenosine receptors.
  • Which of the following is true regarding short-acting beta-2 agonists (SABAs)?

    <p>They should not be used more than twice per week.</p> Signup and view all the answers

    Which incorrect statement might a patient make regarding mucolytic agents?

    <p>These agents can provide great fluid overload.</p> Signup and view all the answers

    What should not be expected from a short-acting beta-2 agonist (SABA)?

    <p>Long-lasting control of asthma attacks</p> Signup and view all the answers

    What is a potential consequence of combining zafirlukast with theophylline?

    <p>Suppressed metabolism of theophylline</p> Signup and view all the answers

    Which is an effect of using SABA too frequently?

    <p>Serious adverse effects</p> Signup and view all the answers

    Which statement indicates a client understands the dietary needs while taking hydrochlorothiazide?

    <p>This medication can cause a loss of potassium.</p> Signup and view all the answers

    Why should a client report increased SABA use to their provider?

    <p>They may need additional medication.</p> Signup and view all the answers

    Which of the following is NOT an interaction to consider with the use of theophylline?

    <p>Zafirlukast</p> Signup and view all the answers

    What adverse effect should a nurse monitor for in a client prescribed a mucolytic agent?

    <p>Bronchospasm</p> Signup and view all the answers

    Why should a client taking hydrochlorothiazide consume potassium-rich foods?

    <p>To avoid hypokalemia</p> Signup and view all the answers

    What is the primary role of albuterol sulfate in treatment?

    <p>To treat acute bronchospasm</p> Signup and view all the answers

    What is a key reason for prescribing enteric-coated aspirin for stroke prophylaxis?

    <p>Enteric-coated medications cause less gastric irritation.</p> Signup and view all the answers

    Which of these medications is correctly paired with its classification?

    <p>Cromolyn - mast cell stabilizer</p> Signup and view all the answers

    What is a common misconception about the effect of potassium when taking hydrochlorothiazide?

    <p>Potassium affects the medication’s effectiveness.</p> Signup and view all the answers

    Why might long-term treatment with glucocorticoids lead to hypertension?

    <p>Due to sodium and water retention.</p> Signup and view all the answers

    Which medication should a nurse anticipate for a client with atrial fibrillation scheduled for cardioversion?

    <p>Diltiazem</p> Signup and view all the answers

    What side effects might a nurse expect from long-term glucocorticoid treatment?

    <p>Restlessness and agitation.</p> Signup and view all the answers

    Which of the following statements about enteric-coated medications is incorrect?

    <p>They enhance gastric absorption of medications.</p> Signup and view all the answers

    Which medication is NOT typically used to treat arrhythmias?

    <p>Amlodipine</p> Signup and view all the answers

    What happens if the coating of an enteric-coated medication fails to dissolve?

    <p>No absorption of the medication will occur.</p> Signup and view all the answers

    Which of the following statements about diltiazem is true?

    <p>It is a calcium channel blocker that lowers blood pressure.</p> Signup and view all the answers

    What adverse effect should a nurse monitor for when administering subcutaneous epinephrine?

    <p>Tachycardia</p> Signup and view all the answers

    What is a possible serious adverse effect of alteplase administration?

    <p>Bleeding</p> Signup and view all the answers

    Which client statement indicates understanding of the nitroglycerin patch application?

    <p>I can place the patch on any area of my body without hair.</p> Signup and view all the answers

    Which symptom is NOT an expected adverse effect of epinephrine?

    <p>Hyperthermia</p> Signup and view all the answers

    Why is bleeding a concern when administering alteplase?

    <p>It can catalyze the conversion of plasminogen to plasmin.</p> Signup and view all the answers

    Which of the following is an incorrect practice regarding the nitroglycerin patch?

    <p>Applying it over a hairy area.</p> Signup and view all the answers

    What is a major action of epinephrine that might cause tachycardia?

    <p>Activation of beta-adrenergic receptors.</p> Signup and view all the answers

    Which statement about alteplase is true?

    <p>It is a thrombolytic agent that dissolves clots.</p> Signup and view all the answers

    Why should the nitroglycerin transdermal patch be applied to hairless skin?

    <p>Hair creates a physical barrier to absorption.</p> Signup and view all the answers

    Which statement about the nitroglycerin patch placement is correct?

    <p>It should not be placed on the same site as a previous patch.</p> Signup and view all the answers

    What is an expected side effect of brompheniramine?

    <p>Dry mouth.</p> Signup and view all the answers

    What advice should the nurse give to alleviate dry mouth caused by brompheniramine?

    <p>Suck on hard, sugarless candy or take frequent sips of liquid.</p> Signup and view all the answers

    What central nervous system effects might a client experience while taking brompheniramine?

    <p>Dizziness and confusion.</p> Signup and view all the answers

    What medication is typically prescribed for a client experiencing unstable angina?

    <p>Nitroglycerin</p> Signup and view all the answers

    Which of the following gastrointestinal disturbances is known and does not need immediate reporting for a client taking brompheniramine?

    <p>Nausea and vomiting.</p> Signup and view all the answers

    What is a potential side effect related to urinary frequency when taking brompheniramine?

    <p>Increased urinary frequency.</p> Signup and view all the answers

    Study Notes

    Theophylline Interactions

    • Zafirlukast suppresses the metabolism of theophylline, leading to potential toxicity.
    • Theophylline should not be used with zafirlukast.

    Hydrochlorothiazide

    • Decreases potassium levels in the body.
    • Requires a potassium-rich diet to avoid hypokalemia.
    • Foods rich in potassium include: bananas, raisins, baked potatoes, pumpkins, and milk.

    Mucolytics

    • Thin mucus secretions.
    • Can irritate airways, causing bronchospasm.
    • Adverse effects can include a cough and thinning mucus secretions.

    Short-Acting Beta-2 Agonists (SABAs)

    • Used for the treatment of asthma attacks.
    • Not for long-term asthma control.
    • If used more than twice a week, a long-acting beta-2 agonist (LABA) should be considered.

    Omalizumab

    • Reduces the number of immunoglobulin E (IgE) molecules on mast cells.
    • Reduces allergic response.

    Glucocorticoids

    • Long-term use can cause hypertension.
    • Can cause restlessness, agitation, anxiety, and irritability.

    Enteric-Coated Aspirin

    • Dissolves in the small intestine, reducing gastric irritation.
    • Protects the stomach lining from the effects of aspirin.

    Diltiazem

    • Calcium channel blocker.
    • Reduces blood pressure.
    • Used during cardioversion to treat atrial fibrillation.

    Epinephrine

    • Adrenergic agonist.
    • Can cause tachycardia and dysrhythmia stimulation.

    Alteplase

    • Thrombolytic medication used to dissolve clots.
    • Can cause bleeding.

    Nitroglycerin Patch

    • Should be applied to hairless skin for optimal absorption.
    • Can cause skin irritation if applied to the same site repeatedly.

    Brompheniramine

    • First-generation antihistamine.
    • Dry mouth can be an expected effect.
    • Can cause gastrointestinal disturbances (nausea, vomiting, loss of appetite, diarrhea, constipation).
    • Can cause central nervous system effects (dizziness, poor coordination, confusion, fatigue) .

    Unstable Angina

    • Nitroglycerin is the medication of choice to treat unstable angina.

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    Description

    This quiz covers key interactions and effects of various pharmacological agents, including theophylline, hydrochlorothiazide, and glucocorticoids. It highlights adverse effects and dietary considerations essential for safe medication use. Test your knowledge on the use of mucolytics, short-acting beta-2 agonists, and omalizumab in asthma management.

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