Pharmacology I: Cardiovascular Pharmacology Quiz
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Questions and Answers

Which channel is responsible for reabsorption in the kidney?

  • Epithelial sodium channel (ENaC) (correct)
  • Sodium-potassium pump
  • Epithelial chloride channel (ECC)
  • Potassium-chloride symporter (KCC)

Where does the acidification of urine primarily occur?

  • Loop of Henle
  • Collecting duct (correct)
  • Distal convoluted tubule (DCT)
  • Proximal convoluted tubule (PCT)

What hormone regulates water reabsorption at the medullary collecting tubules?

  • Thyroxine
  • Parathyroid hormone
  • Aldosterone
  • Antidiuretic hormone (ADH) (correct)

Which of the following is activated by protein kinase A (PKA) in the collecting duct cells?

<p>Aquaporin-2 (AQP2) (A)</p> Signup and view all the answers

What effect do carbonic anhydrase inhibitors have on HCO3- levels?

<p>Lead to HCO3- diuresis (C)</p> Signup and view all the answers

Why are carbonic anhydrase inhibitors contraindicated for patients with hepatic encephalopathy?

<p>They may cause hyperammonemia (C)</p> Signup and view all the answers

What is the primary purpose of the cardiovascular system?

<p>Transporting oxygen, nutrients, hormones, and waste products throughout the body (B)</p> Signup and view all the answers

Which part of the cardiovascular system is responsible for carrying oxygen to body tissues?

<p>Blood (B)</p> Signup and view all the answers

How many atria and ventricles does the heart have?

<p>2 atria, 2 ventricles (D)</p> Signup and view all the answers

Which part of the cardiovascular system is mainly responsible for nutrient/waste product exchange?

<p>Capillaries (C)</p> Signup and view all the answers

What type of drugs are used to treat hypertension according to the content provided?

<p>Diuretics (C)</p> Signup and view all the answers

What is the function of blood vessels in the cardiovascular system?

<p>Oxygen transport and nutrient exchange (D)</p> Signup and view all the answers

Which drug is considered the prototype agent for Carbonic Anhydrase Inhibitors?

<p>Acetazolamide (D)</p> Signup and view all the answers

In which condition would Acetazolamide be used to increase urine pH?

<p>Metabolic Alkalosis (C)</p> Signup and view all the answers

What is a common adverse effect associated with high doses of Acetazolamide?

<p>Nervous System toxicity (B)</p> Signup and view all the answers

Which of the following is a clinical application of Brinzolamide?

<p>Glaucoma (D)</p> Signup and view all the answers

What effect can Acetazolamide have on CSF formation in serious cases?

<p>Reduce CSF formation and pH (A)</p> Signup and view all the answers

What is a potential risk associated with Acetazolamide use in patients with uric acid and cystine issues?

<p>Renal Stones (A)</p> Signup and view all the answers

What is the role of hormones like epinephrine and norepinephrine in the cardiovascular system?

<p>Increase heart rate and cause vasoconstriction (C)</p> Signup and view all the answers

What is the main effect of beta-blockers on the cardiovascular system?

<p>Decrease heart rate and increase contractility (C)</p> Signup and view all the answers

Which pharmacologic target promotes vasodilation by blocking the RAAS system?

<p>Angiotensin Converting Enzyme Inhibitors (A)</p> Signup and view all the answers

How do diuretics affect blood volume and pressure?

<p>Decrease blood volume and pressure (B)</p> Signup and view all the answers

What effect does sympathetic stimulation have on heart rate?

<p>Increases heart rate (D)</p> Signup and view all the answers

Why is understanding cardiovascular physiology essential in managing various cardiovascular disorders?

<p>To effectively manage hypertension, heart failure, angina, and arrhythmia (B)</p> Signup and view all the answers

Which adverse effect is commonly associated with Thiazide Diuretics?

<p>Hypokalemia (C)</p> Signup and view all the answers

What is the main mechanism of action of Potassium-Sparring Diuretics?

<p>Act as a pharmacological antagonist of aldosterone (C)</p> Signup and view all the answers

Which drug is a potassium-sparing diuretic that is known for being cardioprotective?

<p>Eplerenone (B)</p> Signup and view all the answers

What is a common symptom of hyperuricemia?

<p>Impotence (B)</p> Signup and view all the answers

Which diuretic drug included in potassium-sparing diuretics has a short duration of action and requires frequent dosing?

<p>Triamterene (B)</p> Signup and view all the answers

What is the primary reason why Potassium-Sparring Diuretics are contraindicated for patients with liver disease?

<p>They can cause hyperkalemia (C)</p> Signup and view all the answers

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