Pharmacology Fundamentals

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Questions and Answers

Which aspect of pharmacology involves studying the processes of drug absorption, distribution, metabolism, and excretion?

  • Pharmacodynamics
  • Pharmacokinetics (correct)
  • Pharmacotherapeutics
  • Pharmacognosy

If a drug causes haziness or precipitate when mixed in the same syringe, what type of drug interaction is likely occurring?

  • Displacement
  • Synergism
  • Additive Effect
  • Incompatibility (correct)

In the context of pharmacology, what is the meaning of 'pharmakon'?

  • Effect
  • Science
  • Study
  • Medicine or Drug (correct)

Which of the following best describes the focus of pharmacodynamics?

<p>The study of drug effects and mechanisms of action. (D)</p> Signup and view all the answers

For which of the following patients would the half-life of a drug be MOST relevant, when planning the frequency of dosing?

<p>Patients with liver or kidney disease. (B)</p> Signup and view all the answers

Which field focuses on the identification, selection, preservation, and standardization of medical substances?

<p>Pharmacy (C)</p> Signup and view all the answers

If a drug provokes vomiting, into which category would it be classified?

<p>Emetic (D)</p> Signup and view all the answers

Which type of diuretic reduces potassium loss while increasing sodium and water loss?

<p>Potassium-sparing diuretics (C)</p> Signup and view all the answers

Which of the following best describes the action of local anesthetics?

<p>Blocking sensory nerve impulses. (A)</p> Signup and view all the answers

A patient is prescribed a drug with a half-life of 3 hours. How does this influence the dosing schedule, compared to a drug with a 22-hour half-life?

<p>It requires more frequent dosing. (D)</p> Signup and view all the answers

In the context of pharmacology, what does 'hs' typically abbreviate?

<p>At bedtime (C)</p> Signup and view all the answers

Which route of drug administration is indicated by the abbreviation 'i.m'?

<p>Intramuscular (D)</p> Signup and view all the answers

What is the primary consideration when prescribing drugs for neonates, related to appropriate dosage?

<p>Determining dosages based on the neonate's unique physiology. (B)</p> Signup and view all the answers

According to Clark's Rule, which factor is MOST relevant when determining a child's drug dosage?

<p>The child’s weight relative to the average adult weight (D)</p> Signup and view all the answers

Which of the following represents the MOST significant reason for avoiding abbreviations on prescriptions?

<p>To improve clarity and reduce potential errors (A)</p> Signup and view all the answers

What action is MOST aligned to ensure rational drug use, in efforts to minimize waste, according to the principles of pharmacology?

<p>Using clear reasoning and judgement in prescribing the correct drug with the right diagnosis (B)</p> Signup and view all the answers

How do 'sera' function differently from 'toxoids' in providing protection against communicable diseases?

<p>Sera provide passive immunity, while toxoids stimulate active immunity. (D)</p> Signup and view all the answers

When administering intravenous fluids, what primarily determines the importance of precisely controlling the flow rate?

<p>To maintain the correct fluid balance and prevent complications (C)</p> Signup and view all the answers

What is the primary purpose of pharmacovigilance?

<p>To detect, assess, understand, and prevent adverse drug effects (A)</p> Signup and view all the answers

A patient taking tetracycline is also prescribed an antacid. What type of drug interaction is MOST likely to occur?

<p>Antagonistic (B)</p> Signup and view all the answers

How does the term 'drug' defined in pharmacology differ from its everyday usage?

<p>In pharmacology, a drug is any chemical substance used in diagnosis, treatment, or prevention of diseases, while everyday usage is broader. (D)</p> Signup and view all the answers

What did Oswald Schmiedeberg contribute to the field of pharmacology?

<p>He is recognized as the founder of modern pharmacology. (A)</p> Signup and view all the answers

If a patient experiences a perceived improvement after taking a substance with no medicinal properties, which phenomenon is MOST likely demonstrated?

<p>Placebo effect (C)</p> Signup and view all the answers

What is the primary goal of calculating drug dosages and IV infusion rates accurately?

<p>To prevent drug errors and ensure patient safety (D)</p> Signup and view all the answers

According to the principles of good dispensing, what should a healthcare provider confirm FIRST, before dispensing medication?

<p>The order's completeness and appropriateness (B)</p> Signup and view all the answers

In the context of drug interactions, what term describes the combined effect of two drugs being greater than the sum of their individual effects?

<p>Synergism (A)</p> Signup and view all the answers

What is 'chemotherapy' in pharmacological terms?

<p>The effect of drugs targeting microorganisms, parasites, and neoplastic cells. (B)</p> Signup and view all the answers

In which situation is the use of placebos considered ethically problematic, as opposed to laboratory research?

<p>When they introduce deception and dishonesty into the doctor-patient relationship (D)</p> Signup and view all the answers

When might Steroid (Anti-inflammatory steroids) be used with caution because inflammation is the body's way of dealing with pathogenic bacterial invasion?

<p>If the inflammatory process is suppressed, the bacteria will spread to all parts of the body. (B)</p> Signup and view all the answers

A prescription reads 'tab po qod'. How many times should a patient take the tablet?

<p>Every other day (C)</p> Signup and view all the answers

If a child who weighs 10kg and a normal adult are given paracetamol where adult dose is at 500mg, what would be the child's dose based on Clark's rule?

<p>71mg (C)</p> Signup and view all the answers

If a boy is supposed to receive 400mls of 5% dextrose in 8 hours where the IV set delivers 60 drops/ml, what would be the drops per minute?

<p>50 drops per minute (D)</p> Signup and view all the answers

Your prescription requires 100mg of cortisone and 250mg is available in stock in 10ml. How many ml should be prescribed?

<p>4 ml (B)</p> Signup and view all the answers

To calculate the number of capsules needed given a prescription of Ampicillin 500mg, how many capsules should be given given 250mgs per capsule stock is available?

<p>2 (C)</p> Signup and view all the answers

What is a valid principles of good prescription?

<p>Contain sufficient information to permit a pharmacist or a nurse to discover possible errors before the drug is dispensed or administered (B)</p> Signup and view all the answers

Which conditions should rational prescribing and drug use improve according to the text?

<p>Achieve good subscribing, dispensing and compliance in all treatment at the lowest possible cost. (C)</p> Signup and view all the answers

What is 'dispensing' in relation to pharmacology?

<p>Administration at a later time where the client is given medication. (A)</p> Signup and view all the answers

Why might Doctors avoid prescribing higher doses higher of drugs during pregnancy or breast-feeding?

<p>They can be harmful to the foetus or to the infant. (B)</p> Signup and view all the answers

Flashcards

What is Pharmacology?

The study of the interaction of drugs with living organisms, including history, source, properties, dosage, administration, absorption, distribution, action, biotransformation, excretion, uses, and effects.

What is a Drug?

A chemical substance used to diagnose, treat, or prevent disease.

What is Half-Life?

The time required for the body to eliminate 50% of a drug.

What is Clinical Pharmacology?

Evaluation of the pharmacological action of drugs, their administration, and safe dosage range in humans through clinical trials.

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What are Drugs?

Chemicals that alter the functions of living organisms, generally given for the management, prevention, control, or cure of disease.

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What is Pharmacy?

The science of identification, selection, preservation, standardization, compounding, and dispensing of medical substances.

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What is Chemotherapy?

The effect of drugs upon microorganisms, parasites, and neoplastic cells living and multiplying in living organisms.

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What is Toxicology?

The science of poisons; many drugs can act as poisons if taken in large doses, causing harmful, dangerous, or fatal symptoms.

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What is Pharmacopoeia?

An official code containing a selected list of established drugs and medical preparations with descriptions of their physical properties, and tests of their identity, purity, and potency.

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What are General Anesthetics?

Drugs that depress cerebral function by inducing unconsciousness, usually administered intravenously or through inhalation.

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What are Local Anesthetics?

Medicines that block the impulses of sensory nerve fibers, producing instant pain relief in the area of administration without affecting consciousness; usually administered intradermally or subcutaneously.

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What are Intrathecal Anesthetics?

Local anesthetic drugs injected into the spinal column to block sensory impulses below the lumbar region without interfering with consciousness, often given with narcotic drugs.

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What are Diuretics?

Drugs that decrease sodium and water reabsorption by the renal tubules, increasing solute excretion and urinary output.

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What are Osmotic Diuretics?

Diuretics that increase the urinary output volume and reduce sodium (salt) loss.

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What are Potassium-sparing Diuretics?

Diuretics that reduce potassium loss while increasing sodium (Na+) and water (H2O) loss.

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What are Steroids?

Drugs that suppress all inflammatory processes in the body, used with caution due to their potential to suppress the body's defense against pathogenic bacterial invasion.

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What are Tranquilizers?

Drugs that calm patients who present with hyperactivity, excitement, or confusion.

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What are Minor Tranquilizers?

Tranquilizers that have relaxing and tranquilizing effects on patients with anxiety, tension, and fears.

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What are Major Tranquilizers?

Tranquilizers used in patients with severe symptoms of anxiety, tension, and confusion.

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What are Anti-depressants?

Drugs used to treat depression and illnesses linked to unfortunate domestic and social conditions.

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What are Emetics?

Drugs that provoke vomiting, divided into reflex and central types.

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What are Reflex Emetics?

Emetics that induce vomiting by irritating the stomach, e.g., warm salty water.

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What are Central Emetics?

Emetics that induce vomiting by directly irritating the vomiting center in the brain.

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What are Antiemetics?

Drugs used to stop vomiting.

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What is Histamine?

Drugs that stimulate gastric secretion and cause vasodilation of capillaries and arterioles.

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What are Antihistamines?

Drugs that antagonize the action of histamines, often with antiemetic effects and causing drowsiness.

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What are Laxatives?

Drugs that loosen stools or increase peristaltic movement to promote bowel evacuation, classified into bulky, emollient, and irritant types.

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What are Antifungal agents?

Drugs used in the treatment of fungal infections, mostly for topical applications.

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What are Anthelminthics?

Drugs used in the treatment of worm infestations.

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What are Antimalarial drugs?

Drugs used in the treatment of malaria, administered orally, intramuscularly, or intravenously.

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What are Vaccines and antisera?

Drugs that provide protection against certain communicable diseases, divided into toxoids, sera, and antigens.

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What is Toxoid?

Substances given to bring about active immunity, prompting the body to produce antibodies against bacteria or toxins; mainly used for prophylaxis.

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What are Sera?

Preparations that provide passive immunity, often given for treatment, such as tetanus toxoid 0.5ml IM.

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What are Antigens?

Substances used for diagnostic purposes.

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What Anti-tuberculosis Drugs?

Drugs used in the treatment of tuberculosis.

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What is Pharmacotherapeutics?

Scientific study of the use of drugs in the treatment of disease.

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What is Pharmacodynamics?

Study of the biochemical and physiological effects of drugs and their mechanisms of action.

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What is Therapeutic Effect?

The primary effect of a drug.

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What are Secondary Effects?

All other effects, produced by the drug whether desirable or undesirable.

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What are Target sites?

The organs or tissues where drugs exert their greatest action at the cellular level.

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