Pharmacology Final Review
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Questions and Answers

What is the most common side effect of penicillin?

  • Numbness and tingling
  • Diarrhea (correct)
  • Yeast infection
  • Tendon damage
  • What is the purpose of a culture sensitivity test?

  • To measure BUN and creatinine levels
  • To determine the type of bacteria and what can kill it (correct)
  • To check for photosensitivity
  • To check for tendon damage
  • Why should patients avoid dairy products when taking fluoroquinolones like Cipro?

  • To avoid tendon damage
  • To prevent photosensitivity
  • To reduce stomach discomfort
  • Because they interfere with the medication's absorption (correct)
  • What is the $ ext{first}$ step a nurse should take when there is a change in a patient's status?

    <p>Assess the patient</p> Signup and view all the answers

    Which of the following is a common side effect of sulfa drugs?

    <p>Photosensitivity</p> Signup and view all the answers

    Why should patients avoid taking Cipro and Levaquin together?

    <p>They are both fluoroquinolones and should not be administered together</p> Signup and view all the answers

    What is the primary function of insulin?

    <p>Helps pull sugar out of the blood into cells for use</p> Signup and view all the answers

    Which type of insulin has the fastest onset of action?

    <p>Lispro insulin</p> Signup and view all the answers

    What is the primary role of glucagon in regulating blood sugar?

    <p>Triggers the liver to convert stored glycogen into an energy source</p> Signup and view all the answers

    Which antidiabetic medication must be given with food?

    <p>Glipizide</p> Signup and view all the answers

    Which medication is contraindicated for patients with vision problems?

    <p>Antidepressants</p> Signup and view all the answers

    What is the recommended Hemoglobin A1C target for diabetic patients?

    <p>6.0 or lower</p> Signup and view all the answers

    Which sign indicates a potentially dangerous hypoglycemic episode?

    <p>Shaky and anxious</p> Signup and view all the answers

    Which medication is the primary drug used for the treatment of bipolar disorder?

    <p>Lithium</p> Signup and view all the answers

    What is the recommended action if a patient presents with muscle twitching?

    <p>Hold the patient's medications</p> Signup and view all the answers

    Which type of diabetes is associated with darkening skin patches that don't lighten over time?

    <p>Type 2 diabetes</p> Signup and view all the answers

    Which neurotransmitter is known to be decreased in anxiety?

    <p>GABA</p> Signup and view all the answers

    What is the function of Levodopa in the context of Parkinson's?

    <p>Breaks through the blood-brain barrier</p> Signup and view all the answers

    Which neurotransmitter is primarily affected in Alzheimer's disease?

    <p>Acetylcholine</p> Signup and view all the answers

    What is the main purpose of Aricept in Alzheimer's treatment?

    <p>To slow the progression of the disease</p> Signup and view all the answers

    Which neurotransmitter is increased in schizophrenia?

    <p>Dopamine</p> Signup and view all the answers

    'CARbidopa drives the Levodopa' refers to both being:

    <p>Dopamine agonists</p> Signup and view all the answers

    What neurotransmitter is typically decreased in depression?

    <p>Dopamine</p> Signup and view all the answers

    'Agonist' in pharmacology typically means:

    <p>'Works with' or enhances effects</p> Signup and view all the answers

    'Analgesics' are primarily used for what purpose?

    <p>Relieving pain</p> Signup and view all the answers

    What is the main function of benzodiazepine agonists like Buspirone (BuSpar)?

    <p>Boost the effects of benzodiazepines</p> Signup and view all the answers

    What is the primary method of transmission for tuberculosis (TB)?

    <p>Airborne droplets from coughing or sneezing</p> Signup and view all the answers

    Which of the following is the recommended duration of treatment for active tuberculosis (TB)?

    <p>1 year</p> Signup and view all the answers

    What is the primary mechanism of action for antiviral medications?

    <p>They stop viral reproduction</p> Signup and view all the answers

    When should a patient start taking Tamiflu (oseltamivir) for the treatment of influenza?

    <p>Within 24-48 hours of symptom onset</p> Signup and view all the answers

    Which of the following is NOT a common side effect of steroid inhaler use?

    <p>Drowsiness</p> Signup and view all the answers

    What is the first-line treatment approach for asthma?

    <p>Bronchodilators</p> Signup and view all the answers

    Which of the following is a common side effect of metronidazole (Flagyl) treatment?

    <p>Discolored urine</p> Signup and view all the answers

    Which of the following is a recommended patient instruction for taking HIV medications?

    <p>Take the medications as prescribed daily</p> Signup and view all the answers

    Which of the following is a common side effect of prednisone use?

    <p>Increased blood sugar</p> Signup and view all the answers

    Which of the following body systems is primarily affected in type 1 diabetes?

    <p>Pancreas</p> Signup and view all the answers

    Which medication is used to treat alcohol dependence and requires avoidance of alcohol consumption?

    <p>Disulfiram</p> Signup and view all the answers

    Which of the following medications can cause tardive dyskinesia (excessive mouth movement) as a side effect?

    <p>Antipsychotics</p> Signup and view all the answers

    Which laboratory test is typically ordered to monitor for infection and differentiate white blood cell levels?

    <p>Complete Blood Count (CBC) with differential</p> Signup and view all the answers

    Which medication class can affect liver function and requires monitoring of liver enzymes (ALT/AST)?

    <p>All of the above</p> Signup and view all the answers

    Which medication class can cause photosensitivity as a side effect?

    <p>Antidepressants</p> Signup and view all the answers

    Which medication is contraindicated in patients with liver issues?

    <p>Phenazopyridine</p> Signup and view all the answers

    Which of the following is a nursing intervention for administering loop diuretics?

    <p>Monitor sodium and potassium levels</p> Signup and view all the answers

    Which of the following foods is high in potassium and should be encouraged for patients taking loop diuretics?

    <p>All of the above</p> Signup and view all the answers

    Which medication class can cause sexual dysfunction and weight gain, requiring monitoring of weight and cardiac function?

    <p>Antipsychotics</p> Signup and view all the answers

    Which medication class should be taken with caution during pregnancy due to potential effects on fetal tooth development?

    <p>Tetracyclines</p> Signup and view all the answers

    Match the antibiotic-related information with the correct statement:

    <p>Too much antibiotics can cause an overgrowth of flora = Yeast infection/secondary infection/superinfection Common side effect of penicillin = Diarrhea Patients with cephalosporin allergy may also be allergic to = Penicillin Sulfa drugs are associated with = Photosensitivity (stay out the sun)</p> Signup and view all the answers

    Match the medication-related information with the correct statement:

    <p>Oral contraceptives are ineffective if taken while on antibiotic therapy = Do NOT SMOKE! Fluoroquinolones, such as Cipro, can cause tendon damage after prolonged use = Take with food to reduce stomach discomfort with administration Aminoglycosides require monitoring of labs for BUN and creatinine = Cipro and Levaquin are both examples of = Fluoroquinolones. Do not administer together!</p> Signup and view all the answers

    Match the nursing-related information with the correct statement:

    <p>Culture sensitivity involves taking a culture of bacteria to determine its type and reactions to medications = Broad-spectrum meds given initially / Narrow-spectrum meds given once organism is identified Whenever there is a change in a patient's status, the nurse's first step is to = Assess! Z-track method is used for = Intramuscular injections When administering Fluoroquinolones, patients should not take them with juices containing calcium and should avoid sun exposure due to = Photosensitivity</p> Signup and view all the answers

    Match the following medication classes with their primary side effects:

    <p>Antihistamines = Drowsiness Decongestants = Reduced swelling of nasal passages Steroidal inhalers = Thrush Antitussives = Cough suppression</p> Signup and view all the answers

    Match the following diseases with their primary affected body systems:

    <p>Diabetes = Pancreas primarily Type 1 Diabetes = Resembles more of an auto-immune disease Type 2 Diabetes = Happens later in life Tuberculosis (TB) = Transmitted through the air (airborne droplets)</p> Signup and view all the answers

    Match the following medications with their specific instructions or precautions:

    <p>Flagyl (metronidazole) = Swallow pills whole, do not chew or crush Prednisone = Increases blood sugar Cromolyn sodium = Short acting beta adrenergic agonist (SABA) Zorivax (acyclovir) = Do not take with dairy</p> Signup and view all the answers

    Match the following treatment instructions with the corresponding conditions:

    <p>Instruct patient to drink plenty of water = When taking mucolytics Rinse and gargle after use. Do not swallow the water = Steroidal inhalers Warm cream before administration and have another person present during procedure = Best time to administer yeast infection cream is at night Notify doctor of any vision changes, worsening thyroid conditions or changes in renal or kidney functions = Flagyl (metronidazole)</p> Signup and view all the answers

    Match the following medication classes with their specific effects on the body:

    <p>Antivirals = Stop viral reproduction but do not kill viruses Antibiotics = Weakened immune system Antifungals (-azoles) = Liver impact/possible urine discoloration TB drugs = Reddish-orange urine discoloration is normal</p> Signup and view all the answers

    Match the following conditions with their corresponding treatment instructions:

    <p>Anaphylaxis = Call 911 immediately if occurs Diarrhea during pinworm anthelmintic treatment = Common side effect Changes in vision while on anti-TB drugs = Report immediately Adverse reaction to a medication = Hold next dose and notify the doctor</p> Signup and view all the answers

    Match the following medication side effects with their corresponding precautions:

    <p>Increased eye pressure and high blood pressure = Contraindicated in patients with glaucoma Common side effect of steroidal inhaler usage = Rinse and gargle after use. Do not swallow the water Increased blood sugar = Notify doctor of any vision changes, worsening thyroid conditions or changes in renal or kidney functions Thrush from steroidal inhalers = Swallow pills whole, do not chew or crush</p> Signup and view all the answers

    Match the following treatment guidelines with their corresponding medications:

    <p>Continuing taking HIV meds even after getting pregnant = Instruct patient to continue taking HIV meds, even after getting pregnant Monitoring for low heart rate when taking Reyataz = Monitor for low heart rate when taking Reyataz (Trade) atazanavir Taking Tamiflu within 24-48hrs of onset of flu symptoms = Tamiflu (Trade) oseltamivir can only be taken within 24-48hrs of onset of flu symptoms Not cutting, tapering down, or abruptly stopping HIV drug therapy = Do not cut, taper down or abruptly stop taking HIV medications unless instructed by doctor</p> Signup and view all the answers

    Match the following medication classes with their specific patient instructions:

    <p>Avoid dairy products while on drug = (Antivirals) Zorivax (acyclovir) – don’t take with dairy (TB drugs) Isoniazid (INH) = (TB drugs) Commonly used drug for TB (Antihistamines) = (Antihistamines) Contraindicated in patients w/ glaucoma/ causes increased eye pressure/ high blood pressure (Decongestants) = (Decongestants) Rinse and gargle after use. Do not swallow the water. Thrush – common side effect of steroidal inhaler usage</p> Signup and view all the answers

    Match the following insulin types with their peak times and durations:

    <p>NPH insulin = Peak: 4-12hrs, Duration: 12-24hrs Regular insulin = Peak: N/A, Duration: N/A Lispro = Peak: N/A, Duration: N/A</p> Signup and view all the answers

    Match the following diabetes signs/symptoms with their descriptions:

    <p>Polyuria = Increased urination Polydipsia = Increased thirst Polyphagia = Increased hunger Hemoglobin A1C = Test done to monitor blood sugar levels</p> Signup and view all the answers

    Match the following medications with their primary functions:

    <p>Glucotrol = Lowers sugar levels for diabetes Glipizide = Works too fast without food to slow down body synthesis Metformin = Treats type 2 DM, gestational, and polycystic ovary syndrome Buspirone = Binds to serotonin and dopamine receptors</p> Signup and view all the answers

    Match the following terms with their descriptions:

    <p>Glycogenolysis = Triggers liver to convert stored glycogen into an energy source Glucagon = Helps to increase blood sugar/produced in pancreas (combats hypoglycemia) Glycogen = Helps to increase blood sugar (stored in liver) Hemoglobin A1C = Test done to monitor blood sugar levels for the past three months</p> Signup and view all the answers

    Match the following medication instructions with the correct medication names:

    <p>Amitriptyline = Take at bedtime/ do not stop abruptly Glipizide = Must give with food Insulin = Give within 30mins of mealtimes Glucotrol = Give within 30mins of meals</p> Signup and view all the answers

    Match the following symptoms with their corresponding conditions/medications:

    <p>Weakness and lethargy = Lithium toxicity Cold clammy skin = Hypoglycemia Unstable BP, muscle rigidity, hyperpyrexia = Neuroleptic Malignant Syndrome (NMS) Shaky/anxious = Hypoglycemia</p> Signup and view all the answers

    Match the following medications with their adverse effects/side effects:

    <p>SSRIs = Weight gain Antidepressants = Contraindicated for patients with vision problems Lithium = **Note: avoid excessive exercise Metformin = (Trade) (glucophage -generic) – NEPHROTOXIC</p> Signup and view all the answers

    Match the following medication classes with their monitoring requirements:

    <p>Sodium glucose co-transport inhibitors = (monitor for potassium and dehydration) Metformin (biguanide) = (NEPHROTOXIC) Oral contraceptives = (lower the effect of antidiabetic medication) Anti-depressants = (take 10-14 days to work/ Contraindicated: patients w/ vision problems)</p> Signup and view all the answers

    Match the following insulin administration steps with the correct order:

    <p>Inject air into cloudy (NPH) = $\rightarrow$ Withdraw from clear (Reg) Inject air into clear (Reg) = $\rightarrow$ Withdraw from cloudy (NPH) Withdraw from clear (Reg) = $\rightarrow$ Inject air into cloudy (NPH) Withdraw from cloudy (NPH) = $\rightarrow$ Inject air into clear (Reg)</p> Signup and view all the answers

    Match the following medication pairs with their specific patient monitoring requirements:

    <p>Buspirone = (Increases norepinephrine metabolism in brain) Amitriptyline = (Pt teaching: do not stop abruptly) Benzo's (Xanax, Ativan, Valium, Klonopin) = (Common benzos) Insulin administration = (Monitor pt for hypoglycemia, especially during onset)</p> Signup and view all the answers

    Match the neurotransmitter with its role in mental health:

    <p>Serotonin = Decreased in depression Dopamine = Increased in schizophrenia/decreased in Parkinson's Acetylcholine = Decreased in Alzheimer's GABA = Decreased in anxiety</p> Signup and view all the answers

    Match the medication with its primary usage in mental health:

    <p>Aricept (Trade) = Main Alzheimer's med given to slow disease progression Buspirone (BuSpar) = Common benzo agonist for long-term anxiety use Haldol = Antipsychotic usually given for schizophrenia Narcan (Trade) / naloxone (generic) = Antidote for narcotics and benzos</p> Signup and view all the answers

    Match the medication term with its definition:

    <p>Levodopa = Medication to help increase dopamine levels Carbidopa = Breaks through blood-brain barrier and drops blood pressure Rivastigmine = Given in a patch for dementia patients Oxcarbazepine = Anticonvulsant that can kick sodium out of the body</p> Signup and view all the answers

    Match the mental health concept with its description:

    <p>SSRI's = Decreases libido and causes sexual dysfunction in depression meds Tricyclic antidepressants = Can affect vision and contraindicated in patients with glaucoma Benzo's = Monitor for dizziness and orthostatic hypotension MAOIs = Last resort med for acute mental episodes, requires fasting before starting therapy</p> Signup and view all the answers

    Match the drug interaction warning with the correct medication:

    <p>Don't take with cough syrup = Aricept (Trade) Avoid mixing classes of mental health drugs = MAOIs No bueno for alcoholism = Benzo's Can cause cardiac issues if taken with OTC meds, use with caution together = Aricept (Trade)</p> Signup and view all the answers

    Match the neurotransmitter term with its effect:

    <p>Dopamine agonist = Works with dopamine to enhance effect, can exacerbate depression and psychosis Benzo agonist = Enhances the effect of benzodiazepines like Xanax Benzodiazepine agonist = Enhances the calming effect of benzos, boosts serotonin and dopamine Upper vs. downer neurotransmitters = Dopamine is an upper, serotonin is a downer</p> Signup and view all the answers

    Match the drug overdose risk with the correct warning:

    <p>May miscarry or have birth defects if Preggo's overdose = Pregnant patients who overdose on medications Hold med and call PCP if twitching or movement after crossing blood-brain barrier meds = Medications that are meant to cross the blood-brain barrier Never abruptly stop antidepressants due to jerky movements/restlessness risk = Antidepressants that affect the brain/nervous system Monitor sodium content and liver function for anticonvulsant meds = 'Most seizure meds' that require monitoring for sodium levels</p> Signup and view all the answers

    Match the medication instruction with its corresponding effect:

    <p>Give until antidepressant builds up in patient's system = Benzo's given until another medication accumulates in the body Refrain from mixing classes of mental health drugs = 'Mental health drugs' instruction to avoid combining different classes of medications Monitor vitals, weight, and suicide risk for Tricyclic antidepressants = 'Tricyclic antidepressants' need close monitoring for vital signs, weight, and suicidal thoughts Monitor for muscle rigidity and have crash cart nearby = 'Any drug' that may lead to muscle rigidity requiring emergency measures</p> Signup and view all the answers

    Match the medication class with its effect on fetal development:

    <p>No bueno for preggo's, especially alcoholism = 'Benzo's' class that has negative effects on pregnant patients and those with alcoholism Caution due to potential effects on fetal tooth development = 'MAOIs' that require caution during pregnancy due to risks to fetal tooth development Do not mix with anything! = 'MAOIs' as a drug class that should not be combined with other medications Avoid taking Cipro and Levaquin together = 'Sulfa drugs' as a class known for causing side effects if combined</p> Signup and view all the answers

    Match the medication with its primary side effect:

    <p>Clozapine = Monitor patient for any changes in WBC levels Valproate (valproic acid) = Monitor for liver function Phenazopyridine = Contraindicated in patients with liver issues Reglan = Take on empty stomach</p> Signup and view all the answers

    Match the medication instruction with the correct drug:

    <p>Bactrim = Increase fluids to reduce crystallization (crystalluria) Nitro patch = Keep in original dark glass bottle Famotidine = Don't smoke Nitro = Before administration, shave patient</p> Signup and view all the answers

    Match the medication class with its common side effect:

    <p>Anti-depressants = Can cause cardiac issues, do EKG prior to treatment Seizure meds = Monitor for rash/hives, can indicate life-threatening episode Hormone replacement for menopause = Headaches, breast pain/tenderness, unexpected vaginal bleeding or spotting, mood changes Common side effects of weed = Changes in mood, impaired body movement, impaired memory</p> Signup and view all the answers

    Match the nursing intervention with the corresponding drug action:

    <p>Loop diuretics = Give in the morning, administer slowly via IV to prevent hypotension, monitor sodium and potassium levels Thiazides = Decrease sodium reabsorption Tetracycline = Permanently stains buds of teeth of baby, avoid in pregnant women Statins = Best to take at night, do not take with grapefruit juice or alcohol</p> Signup and view all the answers

    Match the medical condition with the appropriate medication instruction:

    <p>Jaundice = Sign of liver issue Dehydration = Thirst, dark yellow urine, decreased urination, dizziness, lightheadedness, tiredness Signs of successful thyroid hormone therapy = Initial symptoms decrease Thyroid meds during pregnancy/breastfeeding = Given during pregnancy but not during breastfeeding, taken lifelong</p> Signup and view all the answers

    Match the medication with its specific administration instruction:

    <p>EPI PENS = Around age 5 = age for patient teaching 6mo.old injection site = Upper thigh Vials = Push air into before withdrawal Narc patches = Document time and place of administration</p> Signup and view all the answers

    Match the following medication side effects with the correct medication:

    <p>Photosensitivity = Sulfa drugs Tendon damage = Fluoroquinolones Diarrhea = Penicillin Numbness and tingling in hands/feet = Cipro</p> Signup and view all the answers

    Match the nursing intervention with the correct situation:

    <p>Z-track method for injections = Intramuscular injections First step when patient's status changes = Assessing Common labs to monitor with aminoglycosides = BUN and creatinine Patient education for fluoroquinolones = Fluid intake, sun exposure, dairy products</p> Signup and view all the answers

    Match the medication-related instructions with the corresponding medications:

    <p>Avoid smoking while on therapy = Oral Contraceptives Do not take with juices containing calcium = Fluoroquinolones Do not administer Cipro and Levaquin together = Fluoroquinolones Ineffective if taken with antibiotics = Oral Contraceptives</p> Signup and view all the answers

    Match the medication allergy information with the correct statement:

    <p>Cephalosporin allergy may lead to penicillin allergy = Patients allergic to penicillin may also be allergic to cephalosporins = Penicillin and cephalosporins share cross-allergenicity = Allergic reaction to cephalosporins indicates potential penicillin allergy =</p> Signup and view all the answers

    Match the medication types with their primary purpose:

    <p>Antibiotics = Treatment of bacterial infections Oral Contraceptives = Prevention of pregnancy Aminoglycosides = Treatment of specific infections Fluoroquinolones = Broad-spectrum antibiotic use</p> Signup and view all the answers

    Match the medication precautions with the correct drug class:

    <p>Caution during pregnancy due to fetal effects on tooth development = May cause weight gain and sexual dysfunction, monitor weight and cardiac function = Potential adverse effects on liver function, avoid in patients with liver issues = Can lead to photosensitivity reactions, protect skin from sun exposure =</p> Signup and view all the answers

    Match the following respiratory medications with their specific side effects:

    <p>Decongestants = Reduce swelling of nasal passages Steroidal inhalers = Rinse and gargle after use. Do not swallow the water Antihistamine = Blocks histamine receptors / can cause drowsiness Mucolytics = Drink plenty of water when taking</p> Signup and view all the answers

    Match the following diabetes types with their characteristics:

    <p>Type 1 Diabetes = Resembles more of an auto-immune disease Type 2 Diabetes = Happens later in life Gestational Diabetes = Occurs during pregnancy LADA (Latent Autoimmune Diabetes in Adults) = Slow onset, autoimmune-related diabetes</p> Signup and view all the answers

    Match the following medication classes with their specific patient instructions:

    <p>TB drugs = Take 1 hour before or 2 hours after eating or taking an antacid HIV drug therapy = Do not cut, taper down or abruptly stop taking unless instructed by doctor Antitussive = Cough suppressant Bronchodilator = First, Steroid - Second</p> Signup and view all the answers

    Match the following medication side effects with their corresponding medications:

    <p>Increased blood sugar = Prednisone Thrush = Steroidal inhalers Reddish-orange urine discoloration = TB drugs Drowsiness / eye pressure increase = Antihistamine</p> Signup and view all the answers

    Match the following antibiotic instructions with their precautions:

    <p>Monitor for anaphylaxis and call 911 if occurs = Sinus infection treatment No alcohol while on drug = Flagyl (metronidazole) Swallow pills whole, do not chew or crush = Penicillin with potassium Notify doctor of vision changes or thyroid conditions = Flagyl (metronidazole)</p> Signup and view all the answers

    Match the insulin type with its peak time characteristics:

    <p>NPH insulin = Onset: 30mins - 4hrs, Peak: 4-12hrs, Duration: 12-24hrs Regular insulin = Onset: 30-60min, Peaks: 2hrs, Duration: appro. 2hrs Lispro insulin = Onset: 15mins Glucagon = Produced in pancreas, triggers liver to convert stored glycogen into an energy source</p> Signup and view all the answers

    Match the medication with its specific patient teaching:

    <p>Glipizide = Must give with food to slow down body synthesis Glucotrol = Give within 30mins of meals to lower sugar levels Metformin = Treats type 2 DM, gestational, and polycystic ovary syndrome Amitriptyline = Take at bedtime and do not stop abruptly</p> Signup and view all the answers

    Match the medication class with its side effect monitoring requirement:

    <p>Sodium glucose co-transport inhibitors = Monitor for potassium and dehydration Insulin = Monitor for hypoglycemia, especially during onset Lithium = Monitor sodium levels for toxicity Buspirone = No specific side effect monitoring required</p> Signup and view all the answers

    Match the mental health medication with its function:

    <p>Lithium = Main drug for bipolar disorder Buspirone = Binds to serotonin and dopamine receptors Amitriptyline = Anti-depressant that requires tapering off Benzo's (Xanax, Ativan, Valium, Klonopin) = Commonly used for anxiety disorders</p> Signup and view all the answers

    Match the diabetes-related symptom with its description:

    <p>Polydipsia = Increased thirst Polyuria = Increased urination Polyphagia = Increased hunger Hemoglobin A1C test result of 6.0 in diabetics = Lower sugar levels for diabetes</p> Signup and view all the answers

    Match the medication term with its definition:

    <p>Nephrotoxic = (Trade) (glucophage -generic), class: biguanide, treats type 2 DM, gestational, and polycystic ovary syndrome Neuroleptic Malignant Syndrome (NMS) = Life-threatening neuro emergency caused by antipsychotic agents Antidepressants = Require tapering off and can cause withdrawal symptoms if stopped abruptly SSRIs adverse effect = Changes to brain chemistry including weight gain and libido issues</p> Signup and view all the answers

    Match the symptom with its associated condition:

    <p>Darkening skin patches in groin, armpits, neck = Undiagnosed Diabetes Cold clammy skin, weakness, headache = Hypoglycemia (below 60) Frequent thirst, urination, fruity breath = Complications of poorly managed diabetes Unstable BP, muscle rigidity, hyperpyrexia = Neuroleptic Malignant Syndrome (NMS)</p> Signup and view all the answers

    Match the lab test range with its corresponding parameter:

    <p>INR - 1.1 or lower = (International Normalized Ratio) clotting measurement Sodium - 135-145mEq/L = (Electrolyte balance) concentration in blood WBC - 4.5K - 11K = (White Blood Cell count) immune system function test Hemoglobin A1C of 5.6 or lower in non-diabetic individual = (Blood sugar monitoring) over past three months</p> Signup and view all the answers

    Match the medication overdose risk with its warning:

    <p>Metformin (glucophage) = (Biguanide class), nephrotoxic risk - frequent labs required if nephrotoxic drug used Insulin administration without checking blood sugar first = (Hypoglycemia risk), monitor for signs especially during onset Oral contraceptives and antidiabetic medication interaction warning = (Decreases antidiabetic effect), monitor blood sugar closely Cipro and Levaquin combination caution for patients due to vision problems = (Avoid taking together), contraindicated in patients with vision issues</p> Signup and view all the answers

    "Clear to cloudy" insulin mixing steps order:

    <p>Inject air into cloudy (NPH), Withdraw from clear (Reg) = Inject air into clear (Reg), Withdraw from cloudy (NPH) = Withdraw from clear (Reg), Inject air into cloudy (NPH) = Withdraw from cloudy (NPH), Inject air into clear (Reg) =</p> Signup and view all the answers

    Match the medication with the associated side effect:

    <p>Antidepressants = Cardiac issues Anti-seizure meds = Rash/hives indicating life-threatening episode Multiple sclerosis meds = Affects immune system Thyroid meds = Monitor liver function</p> Signup and view all the answers

    Match the medication instruction with the correct drug:

    <p>Drink a lot of water with enteric coated capsules, DO NOT CRUSH = Bactrim Apply transdermal patches with gloves on to avoid skin absorption = Nitro patch Rotate injection sites always = Epi pens Take Reglan on an empty stomach = Reglan</p> Signup and view all the answers

    Match the medication type with its primary effect:

    <p>Loop diuretics = Muscle relaxation and increased blood flow Statins = Best taken at night, avoid grapefruit juice/alcohol Thiazides = Decrease sodium reabsorption Phenazopyridine = Contraindicated in liver issues</p> Signup and view all the answers

    Match the medication side effect with the correct medication class:

    <p>Drowsiness, Photosensitivity, Affect sleep patterns, Ortho hypotension = Antidepressants Sexual dysfunction, Weight gain = Antipsychotics Changes in mood, Impaired body movement, Impaired memory = Weed Headaches, Breast pain/tenderness, Unexpected vaginal bleeding, Mood changes = Hormone replacement for menopause</p> Signup and view all the answers

    Match the nursing intervention with the correct loop diuretic action:

    <p>Give in the AM, Administer slowly via IV to prevent hypotension, Monitor sodium and potassium levels = Loop diuretics Check for allergy first, Stay with patient during administration = 9 rights of drug admin Document time and place of administration = Narc patches Push air into vials before withdrawal = Vials</p> Signup and view all the answers

    Match the medication-related information with the correct statement:

    <p>Nitro - keep in original dark glass bottle = Nitro patch Famotidine - don’t smoke = Famotidine Thyroid meds - take lifelong, No breastfeeding = Thyroid meds Anti-thyroid - monitor liver function/check eye color = Anti-thyroid meds</p> Signup and view all the answers

    Match the medication class with its common side effect:

    <p>Diuretics - Causes dilations and muscle relaxation to lower BP = Diuretics Lasix - Don’t miss doses due to frequent urination = Lasix Tetracycline - Photosensitivity and teeth staining in babies = Tetracycline Jaundice - Sign of liver issue in response to meds = Jaundice</p> Signup and view all the answers

    Match the medication pair with its specific patient monitoring requirement:

    <p>Valproate (valproic acid) = Monitor for liver function Lactulose for patients with liver issues = Brings down ammonia levels Thyroid meds = Monitor liver function/check eye color Blood levels test = Determine if drug is at therapeutic range</p> Signup and view all the answers

    Match the medication term with its associated definition:

    <p>Disulfiram = Given for alcohol dependency/avoid alcohol while on drug Clozapine = Antipsychotic/monitor WBC levels for changes Lorazepam = Benzodiazepine that causes sedation Bactrim = Increase fluids to reduce crystallization</p> Signup and view all the answers

    Match the medication class with its main effect on fetal development:

    <p>Thyroid meds = Do not take during breastfeeding but necessary during pregnancy Antidepressants = Can cause cardiac issues in developing fetus if taken during pregnancy Hormone replacement for menopause = May lead to unexpected vaginal bleeding or spotting Lactulose for patients with liver issues = Not recommended during pregnancy due to potential effects on fetal tooth development</p> Signup and view all the answers

    Match the neurotransmitter with its role in mental health:

    <p>Serotonin = Decreased in depression Dopamine = Increased in schizophrenia/decreased in Parkinson’s Acetylcholine = Decreased in Alzheimer's GABA = Decreased in anxiety</p> Signup and view all the answers

    Match the medication with its primary usage:

    <p>Aricept (Trade) = Main Alzheimer’s med Rivastigmine (generic) = Med for dementia given in a patch Oxcarbazepine (generic) = Anticonvulsant Haldol = Antipsychotic usually given via injection</p> Signup and view all the answers

    Match the neurotransmitter with its effect:

    <p>Dopamine = Upper Serotonin = Downer GABA = Relaxation to sleep Acetylcholine = Parasympathetic system</p> Signup and view all the answers

    Match the medication instruction with its corresponding effect:

    <p>Never abruptly stop antidepressants = May present with jerky movements/restlessness Give benzos until antidepressant builds up in system = Monitor for dizziness, orthostatic hypotension SSRIs for depression = Decrease libido Tricyclic antidepressants for depression = Can affect vision</p> Signup and view all the answers

    Match the drug overdose risk with the correct warning:

    <p>Narcs and benzos = No bueno for pregnant individuals MAOIs = Last resort med for acute mental episodes, wait 2 weeks before starting therapy Haldol = Usually given for schizophrenia via injection Lamotrigine = Notify PCP if patient presents with hives</p> Signup and view all the answers

    Match the medication class with its common side effect monitoring requirement:

    <p>Antidepressants = Monitor for suicidal thoughts Seizure medications = Monitor sodium levels Sedatives = Monitor for drowsiness and sedation Benzo agonists like Buspirone (BuSpar) = Enhance the effect of benzos</p> Signup and view all the answers

    Match the medication class with its primary side effect:

    <p>SSRIs and Tricyclic antidepressants = Cause sexual dysfunction Antidepressants in general = Can cause weight gain Tricyclic antidepressants specifically = Affect vision and contraindicated in glaucoma patients Benzo agonists like Buspirone (BuSpar) = Boost serotonin/dopamine</p> Signup and view all the answers

    Match the medication with its specific administration instruction:

    <p>Aricept (Trade) = Don’t take with cough syrup, caution with OTC meds due to cardiac issues Rivastigmine (generic) = Put in a place dementia patients can't reach, usually on the back as a patch Oxcarbazepine (generic) = Monitor sodium content and liver function, can kick sodium out of the body Haldol = Usually given via injection, for schizophrenia</p> Signup and view all the answers

    Match the neurotransmitter with its primary function:

    <p>Acetylcholine = Works on parasympathetic system Epinephrine = Works on sympathetic system Dopamine = Helps with Parkinson’s rigidity / increased in schizophrenia/decreased in Parkinson’s GABA = Relaxation to sleep / decreased in anxiety</p> Signup and view all the answers

    Match the medication instruction with its corresponding effect:

    <p>Narcan (Trade) / Naloxone (generic) = Antidote for narcotics like opioids / Flumazenil is for benzodiazepines Narcs and benzos interaction warning = No bueno for pregnant individuals Pregnant individuals overdose risk warning = May miscarry or baby may have birth defects Narcan overdose risk warning = Might cause twitching or movement after meds that cross blood-brain barrier</p> Signup and view all the answers

    Study Notes

    • Infection Control and Medication Administration*
    • Monitor for anaphylaxis when administering antibiotics for sinus infections and call 911 immediately if it occurs
    • Tuberculosis (TB) is transmitted through airborne droplets and is treated for 1 year for active cases and 6 months for exposure
    • Do not administer any medications with alcohol
    • Antifungals and Yeast Infections*
    • Antifungals have a suffix of -azoles
    • Best time to administer yeast infection cream is at night, after using the bathroom, and with warm cream
    • Griseofulvin (generic) or Grifulvin V (Trade) is used to treat ringworm, but may affect the liver and cause urine discoloration
    • Antivirals and HIV*
    • Antivirals are virustatic, not virucidal, and stop viral reproduction but do not kill viruses
    • Pregnant women should avoid RSV
    • Zorivax (Trade) or acyclovir (generic) should not be taken with dairy products
    • First sign of anaphylaxis is facial swelling
    • Antivirals are used to treat HIV, and patients should continue taking HIV medications even after getting pregnant
    • Medication Safety*
    • Never abruptly stop taking medications, especially cardiac meds
    • When taking Reyataz (Trade) or atazanavir (generic), monitor for low heart rate
    • Tamiflu (Trade) or oseltamivir (generic) can only be taken within 24-48 hours of flu symptom onset
    • Certain situations can cause normal flora to cause infection, such as flora in the wrong area, antibiotic therapy, chemotherapy, radiation therapy, or a weakened immune system
    • TB Medications*
    • Instruct patients taking TB drugs to not drink alcohol, take as directed, report new symptoms, and monitor for reddish-orange urine discoloration
    • Flagyl (Trade) or metronidazole (generic) should be swallowed whole, taken 1 hour before or 2 hours after eating, and may cause drowsiness
    • HIV Medications*
    • Instruct patients taking HIV medications to take as prescribed, not to cut, taper, or stop taking meds abruptly, as this can lead to drug resistance
    • Respiratory Medications*
    • Antihistamines block histamine receptors and can cause drowsiness, and are contraindicated in patients with glaucoma
    • Decongestants reduce swelling of nasal passages
    • Steroidal inhalers require rinsing and gargling after use, and can cause thrush as a side effect
    • Cromolyn sodium is a short-acting beta adrenergic agonist (SABA) used to prevent exercise-induced asthma attacks
    • Diabetes Medications*
    • Insulin regulates sugar, fat, and protein, primarily sugar, at the cellular level
    • Always check blood sugar before insulin administration
    • The three P's of diabetes are polydipsia (increased thirst), polyuria (increased urination), and polyphagia (increased hunger)
    • Regular insulin works fast and is short-acting, NPH insulin works slow and is long-acting, and Lispro insulin works rapidly
    • Insulin peak times vary depending on the type of insulin
    • Pharmacology Final Review*
    • Antibiotics can cause an overgrowth of flora, and are often given with antifungals to prevent superinfections
    • Penicillin can cause diarrhea and interacts with oral contraceptives
    • Ciprofloxacin can cause tendon damage and interacts with dairy products
    • Sulfa drugs can cause photosensitivity and lower blood sugar
    • Aminoglycosides require monitoring of BUN and creatinine levels
    • Hormone Regulation*
    • Glucagon helps increase blood sugar and is produced in the pancreas
    • Glycogen helps increase blood sugar and is stored in the liver
    • Glipizide must be given with food and works too fast without food
    • Metformin (Trade) or glucophage (generic) treats type 2 diabetes, gestational diabetes, and polycystic ovary syndrome, and is nephrotoxic
    • Medication and Lab Interactions*
    • Certain medications, such as glucophage, are nephrotoxic and require frequent lab monitoring
    • Oral contraceptives lower the effect of antidiabetic medications
    • Sodium glucose co-transport inhibitors work on the kidneys to prevent reabsorption of glucose
    • Hemoglobin A1C is a test used to monitor blood sugar levels for the past three months### Antibiotics and Sinus Infections
    • Monitor for anaphylaxis when giving antibiotics for sinus infections and call 911 immediately if occurs

    Tuberculosis (TB)

    • Transmitted through the air (airborne droplets)
    • Treated for 1 year for active TB, 6 months for exposure

    Medication Administration

    • DO NOT administer ANY medications with alcohol

    Antifungals

    • Suffix is -azoles
    • Examples: Grifulvin V (Trade), Griseofulvin (generic)

    Ringworm Treatment

    • Treat with Griseofulvin (generic), Grifulvin V (Trade)
    • Affects the liver and may cause urine discoloration

    Diarrhea

    • Common side effect of pinworm anthelmintic treatment

    Travel Vaccinations

    • Get all inoculations before visiting foreign countries (prophylactic - intended to prevent disease)

    Anti-TB Drugs

    • Report changes in vision while on anti-TB drugs
    • Isoniazid (INH) is a common drug used for TB

    Antivirals

    • All antivirals are virustatic, not virucidal, meaning they don't kill viruses, but stop viral reproduction
    • Used to treat HIV

    Pregnancy and HIV

    • Instruct patient to continue taking HIV meds, even after getting pregnant
    • HIV medications affect the liver

    Medication Side Effects

    • Never abruptly stop taking any medications, especially cardiac meds
    • Monitor for low heart rate when taking Reyataz (Trade) atazanavir (generic)

    Tamiflu

    • Can only be taken with 24-48 hours of onset of flu symptoms

    Body's Normal Flora

    • Can cause infection when in the wrong area, after antibiotic therapy, chemotherapy, radiation therapy, or with a weakened immune system

    TB Medication Instructions

    • Instruct patient to:
      • Not drink alcohol while on the drug
      • Take as directed
      • Take at the same time every day
      • Report any new symptoms
      • Note that reddish-orange urine discoloration is normal
      • Take 1 hour before or 2 hours after eating or taking an antacid

    Flagyl Medication Instructions

    • Instruct patient to:
      • Swallow pills whole, do not chew or crush
      • Take 1 hour before or 2 hours after eating for best absorption
      • Do not drink alcohol while on the drug
      • Notify doctor of any vision changes, worsening thyroid conditions, or changes in renal or kidney functions

    HIV Medication Instructions

    • Instruct patient to:
      • Take the drug as prescribed daily to reduce potential drug resistance
      • Do not cut, taper down, or abruptly stop taking unless instructed by the doctor
      • Taking too little of the drug can lead to drug resistance

    Antihistamines

    • Blocks histamine receptors, can cause drowsiness
    • Contraindicated in patients with glaucoma, causes increased eye pressure, and high blood pressure

    Decongestants

    • Reduce swelling of nasal passages

    Steroidal Inhalers

    • Rinse and gargle after use, do not swallow the water
    • Thrush is a common side effect of steroidal inhaler usage

    Prednisone

    • Increases blood sugar

    Patients with Liver Disease

    • Cannot use leukotriene inhalers

    Cromolyn Sodium

    • Short-acting beta-2 agonist (SABA), used to prevent exercise-induced asthma attack

    Mucolytics

    • Drink plenty of water when taking mucolytics
    • Newborns to 1-year-olds are most at risk for mucolytic toxicity

    Antitussives

    • Given to relieve pain in two ways:
      • Changes patient's perception of the pain
      • Reduces painful stimuli at the source

    Analgesics

    • Given to relieve pain in two ways:
      • Changes patient's perception of the pain
      • Reduces painful stimuli at the source

    Benzodiazepines

    • Works against or blocks the effects of another drug
    • Examples: Buspirone (BuSpar), Xanax

    Dopamine

    • Works with dopamine to enhance the effect
    • Can exacerbate depression and psychosis

    Medication Interactions

    • Never abruptly stop antidepressants because they affect the brain/nervous system
    • Monitor for jerky movements, restlessness, and suicidal thoughts
    • Give benzodiazepines until antidepressant builds up in the patient's system

    Antidepressants

    • SSRI's decrease libido
    • Monitor for suicidal thoughts
    • Generally takes about 14 days to work
    • Can't stop abruptly
    • Causes sexual dysfunction
    • Changes brain chemistry
    • Can cause weight gain

    Tricyclic Antidepressants

    • Can affect vision
    • Contraindicated in patients with glaucoma (increases intraocular pressure)
    • Monitor vitals and weight
    • Monitor for suicide

    Serotonin Syndrome

    • Monitor for 24-72 hours after initial administration
    • SSRI's take about 2 weeks to work

    Mental Health

    • Refrain from mixing medication classes
    • MAOI's are a last resort medication for acute mental episodes
    • patient must wait 2 weeks (fast from all other antipsychotics) before starting therapy

    Haldol

    • Antipsychotic, usually given via injection
    • Usually given for schizophrenia

    Alzheimer's

    • Form of dementia, gets progressively worse
    • Main medication is Aricept (Trade)
    • Given to slow the progression of the disease and help the patient cope with the signs and symptoms
    • Don't take with cough syrup
    • Can cause cardiac issues if given with OTC medications (USE WITH CAUTION TOGETHER)

    Rivastigmine

    • Given in a patch, medication for dementia
    • Put in a place the patient can't reach (usually the back)

    Oxcarbazepine

    • Anticonvulsant, monitor sodium content (can kick sodium out of the body)
    • Monitor liver function (10-35mcg/normal range)

    Sedatives

    • Relax and help with sleep, usually used for insomnia
    • Examples: Xanax, benzodiazepine
    • HIGH ADDICTION POTENTIAL

    Narcan

    • Antidote for narcotics, Flumazenil for benzodiazepines
    • Examples: Narcan (Trade), Naloxone (generic)

    Pregnancy and Opioids

    • No bueno for preggo's (Benzodiazepines are also not good for preggo's)
    • If there is a choice between saving the mom or the fetus, the mom is priority

    Agonist and Antagonist

    • Agonist: Works with/enhances the effect
    • Antagonist: Works against/ blocks or reverses the effects### Mental Health Medications
    • Tardive dyskinesia: a potential side effect of some antipsychotics, causing excessive mouth movement; treated with Cogentin
    • Disulfiram: given for alcohol dependency, but avoid using alcohol while on this drug
    • Clozapine: antipsychotic, monitor patient for changes in WBCs levels
    • CBC w/ differential: a test done to check for infection and break down specific WBC levels

    Antidepressants

    • Can cause cardiac issues, so do EKG prior to and throughout treatment
    • Side effects:
      • Drowsiness
      • Photosensitivity
      • Affecting sleep patterns
      • Orthostatic hypotension
    • Monitor for suicidal thoughts and sexual dysfunction

    Seizure Medications

    • Monitor for rash, hives, and signs of Stevens-Johnson syndrome
    • Valproate (valproic acid): antiepileptic medication, monitor for liver function
    • Bactrim: increase fluids to reduce crystallization (crystalluria)

    Administration of Medications

    • Always check for allergy before administering a medication
    • Rotate injection sites
    • Use gloves when applying transdermal patches
    • Check the 9 rights of drug administration before giving a medication
    • Nitro patch: shave patient before administration (real-world scenario)
    • Narcotic patches: document time and place of administration
    • Drink plenty of water with enteric-coated capsules, and do not crush

    Insulin and Diabetes

    • Insulin regulates sugar, fat, and protein, but primarily sugar, at the cellular level
    • ALWAYS check blood sugar before insulin administration
    • Three P's of diabetes:
      • Polydipsia: increased thirst
      • Polyuria: increased urination
      • Polyphagia: increased hunger
    • Types of insulin:
      • Regular insulin: short-acting, works within 30 minutes
      • NPH insulin: long-acting, takes hours to work and lasts longer
      • Lispro insulin: rapid-acting, works within 15 minutes
    • Monitor patient for hypoglycemia, especially during onset of insulin

    Other Medications

    • Proscar: smooth muscle relaxant for prostate issues
    • Statins: best taken at night, avoid taking with grapefruit juice or alcohol
    • Loop diuretics: take with potassium
    • Phenazopyridine: contraindicated in patients with liver issues
    • Antacids: best taken with meals or soon after, and at bedtime
    • Reglan: take on an empty stomach
    • Lactulose: brings down ammonia levels in patients with liver issues
    • Thyroid medications: take lifelong, no breastfeeding
    • Antithyroid medications: monitor liver function and check eye color

    Abuse and Dependence

    • High alert drugs: medications that can cause harm if administered in error
    • Signs of successful thyroid hormone therapy: if patient's initial symptoms decrease
    • Take thyroid medications 3 hours before or after meals

    Diabetes Complications

    • Frequent thirst, urination, and hunger
    • Darkening skin patches that don't lighten up over time
    • Complications of poorly managed diabetes: frequent thirst, urination, and infection

    Antipsychotics

    • Lithium: main drug for bipolar, don't take with Lasix
    • Amitriptyline: take at bedtime, don't stop abruptly
    • Buspirone: binds to serotonin and dopamine receptors, increases norepinephrine metabolism in the brain

    Antidepressants

    • Never abruptly stop taking antidepressants, always taper off
    • Adverse effects: weight gain, changes in brain chemistry, lowered libido
    • Neuroleptic Malignant Syndrome (NMS): a life-threatening neuro emergency caused by antipsychotic agents

    Antibiotics

    • Too much can cause an overgrowth of flora, often given with antifungals to avoid superinfections
    • Common side effects: diarrhea, yeast infections
    • Culture sensitivity: taking a culture of a bacteria to determine what type it is and what it reacts to

    Antivirals

    • Are all virustatic, but not virucidal, in that they don't kill viruses, but stop viral reproduction
    • First sign of anaphylaxis: facial swelling
    • If patient presents with an adverse reaction to a medication, hold the next dose and notify the doctor

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    Prepare for your pharmacology final with this review covering topics such as antibiotics, common side effects of penicillin, culture sensitivity, and oral contraceptives. Test your knowledge on crucial concepts in pharmacology.

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