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Pharmacology: Drugs Affecting the Respiratory System

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UnboundNovaculite488
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29 Questions

What is the primary function of non-opioid cough suppressants?

To suppress the cough reflex by numbing the stretch receptors in the respiratory tract

What is a common adverse effect of using adrenergic drugs like phenylephrine?

All of the above

What is the primary cause of excessive nasal secretions and inflamed and swollen nasal mucosa?

Both A and B

What is the anti-inflammatory effect of beclomethasone?

Reduces inflammation in the nasal passages

What is the primary route of administration for beclomethasone?

Nasal inhaler

What is a common adverse effect of dextromethorphan?

Both A and B

What is the primary role of H1-histamine antagonists in the treatment of allergies?

To reverse increased capillary permeability and edema

What is a common adverse effect of first-generation anti-histamines?

Drowsiness

What is the primary mechanism of action of anti-histamines in treating allergic reactions?

Blocking the release of histamine

What is the main difference between first-generation and second-generation anti-histamines?

Second-generation anti-histamines have fewer CNS effects

What is the role of mast cells in asthma?

To release chemical mediators leading to inflammation

What is the effect of stabilizing the mast cell membrane in asthma?

It prevents the release of mediators from mast cells and eosinophils

What is the primary effect of stimulating β2-adrenergic receptors in the smooth muscle of bronchi and bronchioles?

Reduce bronchospasm

Which of the following is NOT a factor that exacerbates asthma?

Corticosteroids

What is the effect of anti-leukotrienes on leukotriene synthesis or receptors?

They inhibit leukotriene synthesis

What is the primary mechanism of action of anti-cholinergic agents in treating asthma?

Blocking the action of acetylcholine

What is the time it takes for glucocorticoids to start taking effect?

After 6 hours

What is the advantage of using inhaled glucocorticoids?

They reduce systemic effects

What is the typical duration of action of salmeterol, a long-acting β2 adrenergic agonist?

Up to 12 hours

What is the primary adverse effect of ipratropium bromide, an anti-cholinergic agent?

Dry mouth

What is a common adverse effect of glucocorticoids?

Oropharyngeal candidiasis

What is the typical route of administration for bronchodilators such as salbutamol and ipratropium bromide?

Inhalation

What is the effect of glucocorticoids on mucous secretion?

They decrease mucous secretion

What is the primary function of antitussive drugs?

Suppressing the cough center in the brainstem

What is a characteristic of a productive cough?

It removes excessive secretions

What is the main difference between opioid and non-opioid antitussives?

Their mechanism of action

Why is codeine converted in the liver?

To convert it to morphine

What is a potential risk for rapid metabolizers of codeine?

Breathing difficulty

What is the primary indication for opioid antitussives?

Nonproductive coughs

Test your knowledge of antitussives, including cough suppressants, productive and nonproductive cough, and their effects on the respiratory system. Learn how these drugs work and their classification into different groups.

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