5 Questions
What is chloramphenicol?
A type of antibiotic
What is the mechanism of action of chloramphenicol?
It inhibits protein synthesis
What is a common side effect of chloramphenicol?
Bone marrow suppression
What is the route of administration of chloramphenicol?
All of the above
What is a contraindication for the use of chloramphenicol?
Porphyria
Study Notes
Chloramphenicol Overview
- Chloramphenicol is a broad-spectrum antibiotic that is effective against a wide range of bacteria, including gram-positive and gram-negative bacteria.
Mechanism of Action
- Chloramphenicol works by inhibiting protein synthesis in bacteria by binding to the 50S ribosomal subunit, thereby preventing the formation of peptide bonds.
Adverse Effects
- A common side effect of chloramphenicol is bone marrow suppression, which can lead to aplastic anemia, a potentially life-threatening condition.
Administration
- Chloramphenicol can be administered orally, intravenously, or topically, depending on the type and severity of the infection being treated.
Contraindications
- Chloramphenicol is contraindicated in patients with a history of aplastic anemia or bone marrow suppression, as well as in pregnant women due to the risk of fetal harm.
This quiz covers the basics of chloramphenicol, a broad-spectrum antibiotic. Learn about its mechanism of action, side effects, route of administration, and contraindications.
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