Pharmacology: Chloramphenicol

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Questions and Answers

What is chloramphenicol?

A type of antifungal
A type of antiviral
A type of antibiotic (correct)
A type of vaccine

What is the mechanism of action of chloramphenicol?

It inhibits folic acid synthesis
It inhibits DNA replication
It inhibits cell wall formation
It inhibits protein synthesis (correct)

What is a common side effect of chloramphenicol?

Diarrhea
Rash
Bone marrow suppression (correct)
Nausea and vomiting

What is the route of administration of chloramphenicol?

<p>All of the above (D)</p> Signup and view all the answers

What is a contraindication for the use of chloramphenicol?

<p>Porphyria (A)</p> Signup and view all the answers

Flashcards

What is chloramphenicol?

An antibiotic medication.

Chloramphenicol's action?

Inhibits protein synthesis in bacteria.

Side effect of chloramphenicol?

Bone marrow suppression.

How is chloramphenicol given?

All of the above.

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Don't use chloramphenicol if...

Porphyria.

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Study Notes

Chloramphenicol Overview

Chloramphenicol is a broad-spectrum antibiotic that is effective against a wide range of bacteria, including gram-positive and gram-negative bacteria.

Mechanism of Action

Chloramphenicol works by inhibiting protein synthesis in bacteria by binding to the 50S ribosomal subunit, thereby preventing the formation of peptide bonds.

Adverse Effects

A common side effect of chloramphenicol is bone marrow suppression, which can lead to aplastic anemia, a potentially life-threatening condition.

Administration

Chloramphenicol can be administered orally, intravenously, or topically, depending on the type and severity of the infection being treated.

Contraindications

Chloramphenicol is contraindicated in patients with a history of aplastic anemia or bone marrow suppression, as well as in pregnant women due to the risk of fetal harm.

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Description

This quiz covers the basics of chloramphenicol, a broad-spectrum antibiotic. Learn about its mechanism of action, side effects, route of administration, and contraindications.