Pharmacology Board Exam Review: Adrenergic Receptors and Sympathomimetics

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What does QISS stand for?

Q=Alpha 1, 1=Alpha 2; S-Beta 1; S = Beta 2

What does QIQ stand for?

Q-M1, 1=M2 Q=M3

What does the mnemonic QISS and QIQ sound like?

Kiss and Kick

How is S represented in QISS?

S = Beta 2 Signup and view all the answers

What does 1 represent in QISS?

1=Alpha 2 Signup and view all the answers

What are the common sympathetic effects associated with septic and cardiogenic shock?

Restlessness, tremor, palpitations, throbbing headache Signup and view all the answers

How does epinephrine differ from norepinephrine in terms of its effect on blood pressure?

Epinephrine causes a greater rise in blood pressure compared to norepinephrine. Signup and view all the answers

What are the potential serious consequences of extreme vasospasm?

Tissue necrosis, arrhythmia, myocardial infarction (MI), ischemia Signup and view all the answers

What is the main difference in the effect of epinephrine and norepinephrine on heart rate?

Epinephrine causes reflex bradycardia, while norepinephrine does not. Signup and view all the answers

What are the main vascular effects of epinephrine and norepinephrine?

Epinephrine causes extreme vasospasm, while norepinephrine increases total peripheral resistance. Signup and view all the answers

What is the function of B.ADRENERGIC RECEPTORS in the body?

Vasoconstriction Signup and view all the answers

What is the effect of B.ADRENERGIC RECEPTORS on the pupillary dilator muscle?

Contraction Signup and view all the answers

How do B.ADRENERGIC RECEPTORS affect CAMP levels?

Decrease Signup and view all the answers

What is the role of norepinephrine in B.ADRENERGIC RECEPTORS?

Nonselective Signup and view all the answers

What is the mechanism of action of sympathomimetics on α1 adrenergic receptors?

Vasoconstriction, increases BP, mydriasis Signup and view all the answers

Which drug cannot cause a cholinergic crisis?

Atropine Signup and view all the answers

What is a side effect of excessive intake of ipratropium bromide?

Hypersalivation Signup and view all the answers

A patient was given five times the normal dose of physostigmine and is manifesting toxicity. What antidote would you give?

Pralidoxime Signup and view all the answers

What are some potential complications of a sharp rise in blood pressure?

cerebral hemorrhage, cardiac arrhythmias Signup and view all the answers

In the context of norepinephrine and blood pressure, what is important to remember?

Norepi a > B Signup and view all the answers

Why is it significant to be cautious with norepinephrine in relation to blood pressure?

It can lead to severe complications like cerebral hemorrhage. Signup and view all the answers

What should healthcare providers bear in mind regarding the impact of norepinephrine on cardiac function?

It can cause cardiac arrhythmias. Signup and view all the answers

How can an abrupt surge in blood pressure affect the brain?

It can result in cerebral hemorrhage. Signup and view all the answers