Pharmacology Basics Quiz
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Questions and Answers

Which term specifically describes the study of natural sources of drugs?

  • Pharmacognosy (correct)
  • Pharmaceutics
  • Medicine
  • Pharmacology
  • What is the primary focus of pharmaceutics within the broader field of pharmacology?

  • Investigating the physiological effects of drugs after they are administered.
  • Examining the natural sources from which drugs are derived.
  • Analyzing the modes of action of different drugs.
  • Studying the preparation, use, and dispensing of medicinal drugs. (correct)
  • If a substance has a physiological effect when introduced into the body, but isn't used in a medical setting, how would it be defined?

  • Drug (correct)
  • Pharmacological agent
  • Pharmaceutical
  • Medicine
  • Which field is concerned with understanding how drugs work within the body?

    <p>Pharmacology (B)</p> Signup and view all the answers

    Which of the following can be considered a source of medication?

    <p>Natural sources (A)</p> Signup and view all the answers

    What is the primary focus of the study of pharmacology?

    <p>The uses, effects, and modes of action of drugs. (A)</p> Signup and view all the answers

    Amongst the options, what is the most accurate classification for medicines?

    <p>Medicines are a subset of drugs used in medicinal settings. (D)</p> Signup and view all the answers

    Which route of drug administration involves placing the medication under the tongue?

    <p>Sublingual (D)</p> Signup and view all the answers

    Which abbreviation indicates that a medication should be administered every day?

    <p>QD (C)</p> Signup and view all the answers

    What does the abbreviation 'NPO' signify in a patient's chart?

    <p>Nothing by mouth (B)</p> Signup and view all the answers

    If a medication order reads 'gtt ii,' what does this indicate?

    <p>Two drops (B)</p> Signup and view all the answers

    A medication is to be given 'TID'. What is the meaning of this abbreviation?

    <p>Three times daily (B)</p> Signup and view all the answers

    In new drug testing, what is the primary focus of Phase 1 trials?

    <p>Assessing pharmacokinetics, toxicity, and safe dosing in a small group of healthy volunteers (D)</p> Signup and view all the answers

    During which phase of drug testing are therapeutic levels and longer-term toxicity potential determined?

    <p>Phase 2 (D)</p> Signup and view all the answers

    If a patient is on a medication 'PRN', what does this indicate for administration?

    <p>As needed (A)</p> Signup and view all the answers

    A drug source obtained from a 'mineral', would be classified as a:

    <p>Synthetic (A)</p> Signup and view all the answers

    What is the primary distinction between a 'medication error' and a 'medication misadventure'?

    <p>A medication error is a failure in the planned process, whereas a misadventure encompasses a broader range of drug-related issues, including errors, reactions and events. (B)</p> Signup and view all the answers

    Which of these incident types was NOT specifically listed in the ISMP Canada analysis as a common medication error?

    <p>Dispensing errors (C)</p> Signup and view all the answers

    An adverse drug reaction (ADR) is best defined as:

    <p>A harmful and unintended reaction to a medication occurring at doses typically used for treatment. (B)</p> Signup and view all the answers

    Which of the following scenarios most accurately reflects a 'sentinel event'?

    <p>A patient who suffers a significant fall after incorrectly administered pain medication. (B)</p> Signup and view all the answers

    What does 'pharmacokinetics' primarily concern within the context of a drug monograph?

    <p>How the body absorbs, distributes, metabolizes, and excretes a drug. (A)</p> Signup and view all the answers

    Which information would be LEAST likely found within a drug monograph?

    <p>Details of specific drug interactions not previously known. (C)</p> Signup and view all the answers

    Within the context of medication safety, what is an 'adverse drug event'?

    <p>Any harm resulting from medication, including effects seen when the drug is given correctly. (C)</p> Signup and view all the answers

    Which scenario is best described as a ‘dose omission’?

    <p>A patient does not receive a required dosage of a medication as it was not administrated at all. (D)</p> Signup and view all the answers

    A drug monograph includes 'special considerations'. This section most likely contains:

    <p>Specific warnings and precautions unique to the drug's use. (B)</p> Signup and view all the answers

    If a medication is described as having a 'mechanism of action', this refers to:

    <p>The specific way in which the drug affects the body at the cellular or system level. (B)</p> Signup and view all the answers

    Which of the following is NOT considered a 'right' of medication administration?

    <p>Right diagnosis (B)</p> Signup and view all the answers

    What is the purpose of using 'tall man' lettering in medication administration?

    <p>To differentiate look-alike/sound-alike medications (B)</p> Signup and view all the answers

    Which of the following factors can contribute to medication errors according to the clinical assessment category?

    <p>Inadequate training or knowledge (A)</p> Signup and view all the answers

    Which is a recommended practice regarding verbal medication orders?

    <p>Read back the orders for confirmation (B)</p> Signup and view all the answers

    What is the primary concern when administering high-alert medications?

    <p>Potential for harm if administered incorrectly (D)</p> Signup and view all the answers

    What is the primary focus of the post-marketing analysis conducted in Phase 4 of drug development?

    <p>Analyzing the drug's long-term side effects and appropriate dosages on the general population. (C)</p> Signup and view all the answers

    Why do orphan drugs often require government subsidization?

    <p>Because their development costs are difficult to recoup due to the small patient populations. (C)</p> Signup and view all the answers

    What does 'off-label' use of a drug refer to?

    <p>Using the drug for a condition that was not part of the drug's original approval. (C)</p> Signup and view all the answers

    What is a 'black box' warning added to a drug's packaging intended to communicate?

    <p>The drug may cause significant harm or death, but the benefits may outweigh the risks when used appropriately. (A)</p> Signup and view all the answers

    What are the recommended temperature storage parameters for many medications?

    <p>Between 5-25°C, avoiding freezing or exposure to UV light. (C)</p> Signup and view all the answers

    Why are some drugs packaged as a powder?

    <p>To allow the drug to maintain its stability before being dissolved in a liquid. (A)</p> Signup and view all the answers

    What potential risk is associated with using a medication past its expiry date?

    <p>The drug may be less potent or more potent. (B)</p> Signup and view all the answers

    What must occur before a drug packaged as a powder can be administered parenterally?

    <p>The drug must be reconstituted with a liquid. (D)</p> Signup and view all the answers

    Why do some medications come in UV protective packaging?

    <p>To prevent degradation of the drug caused by light exposure. (B)</p> Signup and view all the answers

    Which of these options is true regarding off-label drug use?

    <p>It has not been proven to be safe or effective for that condition. (D)</p> Signup and view all the answers

    Flashcards

    Drug

    Any substance that has a physiological effect on the body when ingested or administered.

    Pharmacology

    The study of drugs, including their uses, effects, and how they work.

    Pharmaceutics

    The branch of pharmacology focused on the preparation, use, and sale of medicines.

    Medicine

    Drugs used in a healthcare setting to treat illnesses or manage symptoms.

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    Pharmacognosy

    The study of natural sources of drugs, often from plants or animals.

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    Medication Error

    A mistake made during the administration of medication.

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    Adverse Drug Event (ADE)

    Any harmful or unintended effect caused by a medication.

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    PO

    Given by mouth.

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    IV

    Given directly into a vein.

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    IM

    Given by injection into a muscle.

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    SC or SQ

    Given by injection under the skin.

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    SL

    Given under the tongue.

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    PR

    Given through the rectum.

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    IN

    Given into the nose.

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    IO

    Given into the bone marrow.

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    TD

    Given through the skin.

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    Phase 4 Drug Trials

    The final phase of drug development, involves monitoring a drug's effects on a large population after it's been approved for use.

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    Orphan Drugs

    Drugs designed to treat rare diseases. Often have significant side effects and high costs due to limited market potential.

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    Off-label Use

    Using a drug for a condition other than what it's formally approved for. Not covered by insurance and may not be safe or effective.

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    Black Box Warning

    A serious warning added to a drug's label alerting about potentially dangerous side effects discovered after release.

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    Drug Temperature Storage

    Medications have specific temperature requirements for storage. Many drugs need to be kept within a certain temperature range and can't be frozen.

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    Drug Exposure to Light

    Some drugs are sensitive to light, requiring packaging to protect them from UV rays. This helps maintain their potency.

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    Drug Reconstitution

    Certain drugs need to be mixed with liquid before administration. This process is called reconstitution, and is often necessary for powdered medication.

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    Drug Expiry Dates

    Drugs can degrade over time, losing their effectiveness. It's crucial to check the expiry date before using any medication.

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    Medication safety system

    A system-wide approach to medication safety that emphasizes preventing errors through design, process, and culture.

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    Read-back

    The practice of reading back verbal orders to ensure accuracy, reducing confusion and errors.

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    High-alert medications

    A group of drugs that, if misused, can cause significant harm to the patient, often demanding extra vigilance.

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    Tall man lettering

    Using bold or different font styles for similar-sounding medications to distinguish them visually.

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    Adverse drug event

    Any unintended harm caused by a medication, including incorrect dosage or overdose.

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    Adverse drug reaction

    A harmful unintended reaction to a medication that occurs at normal treatment doses.

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    Sentinel event

    "An unexpected occurrence involving death, serious physical or psychological injury, or the risk thereof."

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    Medication misadventure

    Any incident or hazard associated with medication, including errors, adverse drug reactions, and adverse drug events.

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    Common medication errors

    The analysis of 60 medication events showed that half were related to medication administration, including dose omissions, incorrect infusion rates, incorrect drug administration, wrong drug selection, and dosing or mixing errors.

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    Study Notes

    Introduction to Pharmacology

    • Pharmacology is the branch of medicine concerned with the uses, effects, and modes of action of drugs.
    • Pharmaceutics is the branch of pharmacology that deals with the preparation, use, or sale of medicinal drugs.
    • Pharmacognosy is the study of the natural sources of drugs.

    Requirements

    • Read textbook chapters on prefixes, suffixes, and abbreviations (pp. xxiv-xxx).
    • Read textbook chapter 1 (pp. 1-6).
    • Review chapter questions 1, 2, 3, 4, and 5.
    • Read textbook chapter 4 (pp. 52-66).
    • Review chapter questions 1, 3, 6, and 10.
    • Watch a video on medication administration (8 Rights of Medication Administration, 3:23).
    • Watch a video on medication safety (Dr. Francois deWet, 11:15).

    Objectives

    • Define terms: drug, medicine, pharmacology, pharmacognosy, pharmaceutics, medication error, adverse drug event, and adverse drug reaction.
    • List sources of medications (synthetic, plant, mineral, and animal).
    • Identify common abbreviations used in pharmacology (refer to slide 6 of the presentation).
    • Explain the stages of new drug testing, identify orphan drugs, and explain black box warnings.
    • Describe the paramedic's role in medication handling, storage, and management.
    • Detail the components of a drug monograph (names, classification, mechanism of action, indications, pharmacokinetics, side effects/adverse reactions, contraindications, dosage, how supplied, and special considerations).
    • Discuss medication errors and mitigation strategies.
    • Define and explain the 6 rights of medication administration.

    Pharmacology Definitions

    • Drug: A medicine or substance with a physiological effect when introduced into the body.
    • Pharmacology: The branch of medicine concerning the uses, effects, and modes of action of drugs.
    • Pharmaceutics: The branch of pharmacology concerned with the preparation, use, or sale of medicinal drugs.
    • Medicine: Drugs used in a medical setting.
    • Pharmacognosy: The study of natural sources of drugs.

    Common Pharmaceutical Abbreviations

    • (Abbreviations and their meanings are listed in the provided image)

    Sources of Medication

    • Medications come from synthetic, plant, mineral, and animal sources. (Pie chart)

    New Drug Testing

    • Phase 1: Testing on healthy volunteers to assess pharmacokinetics, toxicity, and safe dosage.
    • Phase 2: Testing on patients with the disease to determine therapeutic levels, longer-term toxicity, and side effects.
    • Phase 3: Testing on a large group of patients to refine therapeutic dosing and potential side effects. Results are evaluated by government bodies.
    • Phase 4: Post-marketing analysis of the drug's effects on the general population.

    New Drugs and Special Labeling

    • Orphan drugs: Developed for rare diseases. Side effects may be significant, and cost of development may not be recouped. Government subsidization can address this.
    • Off-label use: Drug use in a condition other than that for which it was initially approved. This use is not always safe and effective, and may not be covered by insurance.
    • Black box warnings: added to drug packaging when a previously unknown harmful effect emerges after the drug is released on the market. This enables the potential for drug reformulation, if appropriate, to mitigate the risks.

    Drug Storage and Handling

    • Medications have specific storage and handling requirements.
    • Temperature parameters, light, exposure, reconstitution, and expiration dates should be taken into account when handling and storing medications.

    Drug Monograph

    • Drug monograph provides comprehensive details on a drug (image displays example of monograph and details). (e.g., name, classification, mechanism of action, indications, pharmacokinetics, side effects, contraindications, dosage, and special considerations).

    Medication Safety

    • Medication errors have significant consequences (graphic/table displaying these consequences).

    Medication Error

    • Medical error: Failure of a planned action.
    • Medication misadventure: Hazards associated with medication.
    • Adverse drug event: Harm from medication (including overdose or harm at a standard dose).
    • Adverse drug reaction: Unintended harm from a medication at a standard dose.
    • Sentinel event: Unexpected events (death, serious physical or psychological injury, or a risk thereof)

    Medication Errors Detailed

    • An analysis of 60 medication events in Canada showed half were related to administration.
    • Common types of medication errors: Incorrect dose, incorrect rate of drug administration, incorrect drug administered, incorrect or unsafe mixing.

    Medication Error Causes

    • Errors are a result of causes related to clinical assessment, drug preparation and administration, communication, medication storage (image).

    System Failures

    • System failures that lead to errors in medication administration (list/outline of possible failures/issues and examples).

    Potential Pitfalls

    • Issues with verbal orders, patient consent, administration, documentation, and charting rules (outline/examples of possible issues)

    High-Alert Medications

    • High-alert medications should be closely monitored due to potential for harm if administered inappropriately (list of these medications).
    • Consider "look-alike/sound-alike" medications. Example: DOPamine & DOBUTamine, diphenhydRAMINE & dimenhyDRINATE

    Medication Medication Safety Case

    • Paramedic services should evaluate medication storage procedures and identify areas for improvement.

    The “Rights” of Medication Administration

    • Detailed list of the 6 rights: Patient, Medication, Time, Dose, Route, and Documentation.

    The “Rights” Detail

    • Right patient: Ensure patient meets the medication indications (age, weight, clinical condition, allergies). Verify patient history for contraindications.
    • Right medication: Verify correct name/concentration. Verify packaging and check for any labeling issues. Check expiry dates.
    • Right time: Administer at the correct time. Ensure needed assessments, interventions, and crucial information have been considered prior to administration.
    • Right dose: Confirm the proper dosage for the patient, including weight-based calculations if necessary. Consider adjustments based on age or clinical condition.
    • Right route: Verify the correct route of administration is appropriate for the patient.
    • Right documentation: Label all bags and syringes. Document each dosage administered (including the time, dose, and route). Document drug administration in the patient profile.

    Independent Double Check (IDDC)

    • Each step of administration (all 6 "rights") must be independently verified by a second person.
    • All calculations should also be performed independently by each paramedic. This is good practice, regardless of experience level.

    Questions?

    • Contact information provided for questions relating to the material.

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    Description

    Test your knowledge on the fundamental concepts of pharmacology, including drug sources, classifications, and administration methods. This quiz covers various essential topics within the field, from the physiological effects of substances to specific medical abbreviations used in practice.

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