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Questions and Answers
Which term specifically describes the study of natural sources of drugs?
Which term specifically describes the study of natural sources of drugs?
What is the primary focus of pharmaceutics within the broader field of pharmacology?
What is the primary focus of pharmaceutics within the broader field of pharmacology?
If a substance has a physiological effect when introduced into the body, but isn't used in a medical setting, how would it be defined?
If a substance has a physiological effect when introduced into the body, but isn't used in a medical setting, how would it be defined?
Which field is concerned with understanding how drugs work within the body?
Which field is concerned with understanding how drugs work within the body?
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Which of the following can be considered a source of medication?
Which of the following can be considered a source of medication?
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What is the primary focus of the study of pharmacology?
What is the primary focus of the study of pharmacology?
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Amongst the options, what is the most accurate classification for medicines?
Amongst the options, what is the most accurate classification for medicines?
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Which route of drug administration involves placing the medication under the tongue?
Which route of drug administration involves placing the medication under the tongue?
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Which abbreviation indicates that a medication should be administered every day?
Which abbreviation indicates that a medication should be administered every day?
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What does the abbreviation 'NPO' signify in a patient's chart?
What does the abbreviation 'NPO' signify in a patient's chart?
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If a medication order reads 'gtt ii,' what does this indicate?
If a medication order reads 'gtt ii,' what does this indicate?
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A medication is to be given 'TID'. What is the meaning of this abbreviation?
A medication is to be given 'TID'. What is the meaning of this abbreviation?
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In new drug testing, what is the primary focus of Phase 1 trials?
In new drug testing, what is the primary focus of Phase 1 trials?
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During which phase of drug testing are therapeutic levels and longer-term toxicity potential determined?
During which phase of drug testing are therapeutic levels and longer-term toxicity potential determined?
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If a patient is on a medication 'PRN', what does this indicate for administration?
If a patient is on a medication 'PRN', what does this indicate for administration?
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A drug source obtained from a 'mineral', would be classified as a:
A drug source obtained from a 'mineral', would be classified as a:
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What is the primary distinction between a 'medication error' and a 'medication misadventure'?
What is the primary distinction between a 'medication error' and a 'medication misadventure'?
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Which of these incident types was NOT specifically listed in the ISMP Canada analysis as a common medication error?
Which of these incident types was NOT specifically listed in the ISMP Canada analysis as a common medication error?
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An adverse drug reaction (ADR) is best defined as:
An adverse drug reaction (ADR) is best defined as:
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Which of the following scenarios most accurately reflects a 'sentinel event'?
Which of the following scenarios most accurately reflects a 'sentinel event'?
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What does 'pharmacokinetics' primarily concern within the context of a drug monograph?
What does 'pharmacokinetics' primarily concern within the context of a drug monograph?
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Which information would be LEAST likely found within a drug monograph?
Which information would be LEAST likely found within a drug monograph?
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Within the context of medication safety, what is an 'adverse drug event'?
Within the context of medication safety, what is an 'adverse drug event'?
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Which scenario is best described as a ‘dose omission’?
Which scenario is best described as a ‘dose omission’?
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A drug monograph includes 'special considerations'. This section most likely contains:
A drug monograph includes 'special considerations'. This section most likely contains:
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If a medication is described as having a 'mechanism of action', this refers to:
If a medication is described as having a 'mechanism of action', this refers to:
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Which of the following is NOT considered a 'right' of medication administration?
Which of the following is NOT considered a 'right' of medication administration?
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What is the purpose of using 'tall man' lettering in medication administration?
What is the purpose of using 'tall man' lettering in medication administration?
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Which of the following factors can contribute to medication errors according to the clinical assessment category?
Which of the following factors can contribute to medication errors according to the clinical assessment category?
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Which is a recommended practice regarding verbal medication orders?
Which is a recommended practice regarding verbal medication orders?
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What is the primary concern when administering high-alert medications?
What is the primary concern when administering high-alert medications?
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What is the primary focus of the post-marketing analysis conducted in Phase 4 of drug development?
What is the primary focus of the post-marketing analysis conducted in Phase 4 of drug development?
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Why do orphan drugs often require government subsidization?
Why do orphan drugs often require government subsidization?
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What does 'off-label' use of a drug refer to?
What does 'off-label' use of a drug refer to?
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What is a 'black box' warning added to a drug's packaging intended to communicate?
What is a 'black box' warning added to a drug's packaging intended to communicate?
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What are the recommended temperature storage parameters for many medications?
What are the recommended temperature storage parameters for many medications?
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Why are some drugs packaged as a powder?
Why are some drugs packaged as a powder?
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What potential risk is associated with using a medication past its expiry date?
What potential risk is associated with using a medication past its expiry date?
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What must occur before a drug packaged as a powder can be administered parenterally?
What must occur before a drug packaged as a powder can be administered parenterally?
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Why do some medications come in UV protective packaging?
Why do some medications come in UV protective packaging?
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Which of these options is true regarding off-label drug use?
Which of these options is true regarding off-label drug use?
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Flashcards
Drug
Drug
Any substance that has a physiological effect on the body when ingested or administered.
Pharmacology
Pharmacology
The study of drugs, including their uses, effects, and how they work.
Pharmaceutics
Pharmaceutics
The branch of pharmacology focused on the preparation, use, and sale of medicines.
Medicine
Medicine
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Pharmacognosy
Pharmacognosy
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Medication Error
Medication Error
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Adverse Drug Event (ADE)
Adverse Drug Event (ADE)
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PO
PO
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IV
IV
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IM
IM
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SC or SQ
SC or SQ
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SL
SL
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PR
PR
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IN
IN
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IO
IO
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TD
TD
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Phase 4 Drug Trials
Phase 4 Drug Trials
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Orphan Drugs
Orphan Drugs
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Off-label Use
Off-label Use
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Black Box Warning
Black Box Warning
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Drug Temperature Storage
Drug Temperature Storage
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Drug Exposure to Light
Drug Exposure to Light
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Drug Reconstitution
Drug Reconstitution
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Drug Expiry Dates
Drug Expiry Dates
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Medication safety system
Medication safety system
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Read-back
Read-back
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High-alert medications
High-alert medications
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Tall man lettering
Tall man lettering
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Adverse drug event
Adverse drug event
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Adverse drug reaction
Adverse drug reaction
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Sentinel event
Sentinel event
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Medication misadventure
Medication misadventure
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Common medication errors
Common medication errors
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Study Notes
Introduction to Pharmacology
- Pharmacology is the branch of medicine concerned with the uses, effects, and modes of action of drugs.
- Pharmaceutics is the branch of pharmacology that deals with the preparation, use, or sale of medicinal drugs.
- Pharmacognosy is the study of the natural sources of drugs.
Requirements
- Read textbook chapters on prefixes, suffixes, and abbreviations (pp. xxiv-xxx).
- Read textbook chapter 1 (pp. 1-6).
- Review chapter questions 1, 2, 3, 4, and 5.
- Read textbook chapter 4 (pp. 52-66).
- Review chapter questions 1, 3, 6, and 10.
- Watch a video on medication administration (8 Rights of Medication Administration, 3:23).
- Watch a video on medication safety (Dr. Francois deWet, 11:15).
Objectives
- Define terms: drug, medicine, pharmacology, pharmacognosy, pharmaceutics, medication error, adverse drug event, and adverse drug reaction.
- List sources of medications (synthetic, plant, mineral, and animal).
- Identify common abbreviations used in pharmacology (refer to slide 6 of the presentation).
- Explain the stages of new drug testing, identify orphan drugs, and explain black box warnings.
- Describe the paramedic's role in medication handling, storage, and management.
- Detail the components of a drug monograph (names, classification, mechanism of action, indications, pharmacokinetics, side effects/adverse reactions, contraindications, dosage, how supplied, and special considerations).
- Discuss medication errors and mitigation strategies.
- Define and explain the 6 rights of medication administration.
Pharmacology Definitions
- Drug: A medicine or substance with a physiological effect when introduced into the body.
- Pharmacology: The branch of medicine concerning the uses, effects, and modes of action of drugs.
- Pharmaceutics: The branch of pharmacology concerned with the preparation, use, or sale of medicinal drugs.
- Medicine: Drugs used in a medical setting.
- Pharmacognosy: The study of natural sources of drugs.
Common Pharmaceutical Abbreviations
- (Abbreviations and their meanings are listed in the provided image)
Sources of Medication
- Medications come from synthetic, plant, mineral, and animal sources. (Pie chart)
New Drug Testing
- Phase 1: Testing on healthy volunteers to assess pharmacokinetics, toxicity, and safe dosage.
- Phase 2: Testing on patients with the disease to determine therapeutic levels, longer-term toxicity, and side effects.
- Phase 3: Testing on a large group of patients to refine therapeutic dosing and potential side effects. Results are evaluated by government bodies.
- Phase 4: Post-marketing analysis of the drug's effects on the general population.
New Drugs and Special Labeling
- Orphan drugs: Developed for rare diseases. Side effects may be significant, and cost of development may not be recouped. Government subsidization can address this.
- Off-label use: Drug use in a condition other than that for which it was initially approved. This use is not always safe and effective, and may not be covered by insurance.
- Black box warnings: added to drug packaging when a previously unknown harmful effect emerges after the drug is released on the market. This enables the potential for drug reformulation, if appropriate, to mitigate the risks.
Drug Storage and Handling
- Medications have specific storage and handling requirements.
- Temperature parameters, light, exposure, reconstitution, and expiration dates should be taken into account when handling and storing medications.
Drug Monograph
- Drug monograph provides comprehensive details on a drug (image displays example of monograph and details). (e.g., name, classification, mechanism of action, indications, pharmacokinetics, side effects, contraindications, dosage, and special considerations).
Medication Safety
- Medication errors have significant consequences (graphic/table displaying these consequences).
Medication Error
- Medical error: Failure of a planned action.
- Medication misadventure: Hazards associated with medication.
- Adverse drug event: Harm from medication (including overdose or harm at a standard dose).
- Adverse drug reaction: Unintended harm from a medication at a standard dose.
- Sentinel event: Unexpected events (death, serious physical or psychological injury, or a risk thereof)
Medication Errors Detailed
- An analysis of 60 medication events in Canada showed half were related to administration.
- Common types of medication errors: Incorrect dose, incorrect rate of drug administration, incorrect drug administered, incorrect or unsafe mixing.
Medication Error Causes
- Errors are a result of causes related to clinical assessment, drug preparation and administration, communication, medication storage (image).
System Failures
- System failures that lead to errors in medication administration (list/outline of possible failures/issues and examples).
Potential Pitfalls
- Issues with verbal orders, patient consent, administration, documentation, and charting rules (outline/examples of possible issues)
High-Alert Medications
- High-alert medications should be closely monitored due to potential for harm if administered inappropriately (list of these medications).
- Consider "look-alike/sound-alike" medications. Example: DOPamine & DOBUTamine, diphenhydRAMINE & dimenhyDRINATE
Medication Medication Safety Case
- Paramedic services should evaluate medication storage procedures and identify areas for improvement.
The “Rights” of Medication Administration
- Detailed list of the 6 rights: Patient, Medication, Time, Dose, Route, and Documentation.
The “Rights” Detail
- Right patient: Ensure patient meets the medication indications (age, weight, clinical condition, allergies). Verify patient history for contraindications.
- Right medication: Verify correct name/concentration. Verify packaging and check for any labeling issues. Check expiry dates.
- Right time: Administer at the correct time. Ensure needed assessments, interventions, and crucial information have been considered prior to administration.
- Right dose: Confirm the proper dosage for the patient, including weight-based calculations if necessary. Consider adjustments based on age or clinical condition.
- Right route: Verify the correct route of administration is appropriate for the patient.
- Right documentation: Label all bags and syringes. Document each dosage administered (including the time, dose, and route). Document drug administration in the patient profile.
Independent Double Check (IDDC)
- Each step of administration (all 6 "rights") must be independently verified by a second person.
- All calculations should also be performed independently by each paramedic. This is good practice, regardless of experience level.
Questions?
- Contact information provided for questions relating to the material.
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Description
Test your knowledge on the fundamental concepts of pharmacology, including drug sources, classifications, and administration methods. This quiz covers various essential topics within the field, from the physiological effects of substances to specific medical abbreviations used in practice.