Pharmacology: Antihypertensives and Diuretics Quiz
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Questions and Answers

Which adverse effect is common to both Ezetimibe and Fibric Acid Derivatives?

  • Fatigue
  • Joint pains (correct)
  • Skin rash
  • Severe flushing

What is a potential adverse effect of Nicotinic Acid Derivatives?

  • Cholelithiasis
  • Flu like symptoms
  • Allergy (correct)
  • Angina

Which cholesterol level is considered normal for HDL according to the nursing implications provided?

  • Less than 30 mg/dL
  • 30 - 75 mg/dL (correct)
  • Less than 150 mg/dL
  • More than 75 mg/dL

Which lipoprotein requires fasting before blood draw according to the information given?

<p>LDL (B)</p> Signup and view all the answers

Which combination product includes Ezetimibe?

<p>Vytorin (D)</p> Signup and view all the answers

What is the action of Fibric Acid Derivatives?

<p>Decrease hepatic triglyceride synthesis (B)</p> Signup and view all the answers

Which adverse effect of Fibric Acid Derivatives affects the skin?

<p>Skin rash (C)</p> Signup and view all the answers

What is the primary action of Nicotinic Acid Derivatives?

<p>Decrease hepatic triglyceride synthesis (D)</p> Signup and view all the answers

Which class of drugs is primarily used to manage hypertension by balancing sodium and water in the kidneys?

<p>Diuretics (C)</p> Signup and view all the answers

Which type of drug blocks the secretory action of the sympathetic nervous system?

<p>Antiadrenergic: Central Acting (B)</p> Signup and view all the answers

Which drug class acts on the smooth muscle layer of blood vessels and is used for severe hypertension and emergencies?

<p>Peripheral Vasodilators (B)</p> Signup and view all the answers

Which drug class primarily blocks beta adrenergic receptors and is used for hypertension, angina, and migraines?

<p>Antiadrenergics/Sympatholytics (C)</p> Signup and view all the answers

Which antiadrenergic drug class blocks both epinephrine and norepinephrine actions?

<p>Peripheral Vasodilators (A)</p> Signup and view all the answers

Which antiadrenergic drug class specifically acts peripherally by blocking alpha adrenergic receptors?

<p>Peripheral Vasodilators (D)</p> Signup and view all the answers

Which drug class is specifically indicated for hypertension, congestive heart failure (CHF), post myocardial infarction (MI), and diabetes?

<p>Diuretics (D)</p> Signup and view all the answers

Which Antiadrenergic drug class is considered 'Central Acting'?

<p>Antiadrenergics/Sympatholytics (C)</p> Signup and view all the answers

Which drug class includes medications like Amlodipine, Diltiazem, and Verapamil that are commonly used for hypertension and angina?

<p>Calcium Channel Blockers (D)</p> Signup and view all the answers

Which drug class is known for balancing sodium and water in the kidneys to help manage hypertension?

<p>Diuretics (A)</p> Signup and view all the answers

Which drug is the drug of choice for hypertensive crisis?

<p>Nitroprusside (D)</p> Signup and view all the answers

What is the primary action of angiotensin converting enzyme inhibitors (ACE-I)?

<p>Inhibit ACE from converting angiotensin I into angiotensin II (D)</p> Signup and view all the answers

Which of the following is an adverse effect of statins (HMG-CoA Reductase Inhibitors)?

<p>Muscle pain and cramps (D)</p> Signup and view all the answers

What is the main action of bile acid sequestrants?

<p>Form a complex with bile (C)</p> Signup and view all the answers

Which drug prevents aldosterone binding at the mineralocorticoid receptor?

<p>Eplerenone (D)</p> Signup and view all the answers

What is the primary action of renin inhibitors?

<p>Directly inhibit renin (B)</p> Signup and view all the answers

Which class of drugs is indicated for shock by increasing heart rate and force of contraction?

<p>Antihypotensives (C)</p> Signup and view all the answers

Which antihypotensive drug mimics epinephrine and norepinephrine actions?

<p>Dobutamine (C)</p> Signup and view all the answers

What symptom is associated with angiotensin converting enzyme inhibitors (ACE-I) adverse drug reactions?

<p>Dry cough (B)</p> Signup and view all the answers

What is the primary role of Peripheral Vasodilators in nursing implications?

<p>Foster circulation (D)</p> Signup and view all the answers

Which adverse effect is common to both Nicotinic Acid Derivatives and Fibric Acid Derivatives?

<p>Nausea and vomiting (A)</p> Signup and view all the answers

What is the primary action of Ezetimibe (Zetia)?

<p>Decrease hepatic triglyceride synthesis (D)</p> Signup and view all the answers

Which drug class includes Gemfibrozil (Lopid) and Fenofibrate (Tricor)?

<p>Fibric Acid Derivatives (A)</p> Signup and view all the answers

What is a common adverse effect of Nicotinic Acid Derivatives?

<p>Nausea and vomiting (D)</p> Signup and view all the answers

What is a nursing implication related to cholesterol levels?

<p>HDL 30 - 75 mg/dL (A)</p> Signup and view all the answers

Which drug is a combination product consisting of Amlodipine and Atorvastatin?

<p>Caduet (C)</p> Signup and view all the answers

What is a potential adverse effect of Ezetimibe and Simvastatin (Vytorin) combination product?

<p>Cardiac arrhythmia (C)</p> Signup and view all the answers

Which action is NOT associated with Nicotinic Acid Derivatives?

<p>Decreases hepatic triglyceride synthesis (A)</p> Signup and view all the answers

What is a key nursing implication regarding lipoprotein blood draw timing?

<ul> <li>No fasting needed for total cholesterol test (C)</li> </ul> Signup and view all the answers

Which antihypertensive drug class is indicated for managing hypertension, angina, arrhythmias, migraines, hyperthyroidism, panic attacks, and post myocardial infarction?

<p>Beta Adrenergic Blockers (A)</p> Signup and view all the answers

Which peripheral acting antiadrenergic drug class specifically blocks alpha adrenergic receptors and is indicated for hypertension and Raynaud’s disease?

<p>Antiadrenergics/Sympatholytics (C)</p> Signup and view all the answers

In the context of antihypotensive drugs, which medication acts on the smooth muscle layer of blood vessels and is indicated for severe hypertension and emergencies?

<p>Peripheral Vasodilators (D)</p> Signup and view all the answers

Which antiadrenergic drug specifically blocks the action of both epinephrine and norepinephrine?

<p>Central Acting Antiadrenergics (C)</p> Signup and view all the answers

What is the primary role of diuretics in managing hypertension?

<p>Removing Na and H2O (A)</p> Signup and view all the answers

Which calcium channel blockers are indicated for hypertension, angina, and Raynaud’s disease?

<p>Terazosin (A)</p> Signup and view all the answers

Which antiadrenergic drug belongs to the central acting group and includes drugs like Methyldopa and Clonidine?

<p>Antiadrenergic: Central Acting (B)</p> Signup and view all the answers

Which drug class balances sodium and water in the kidneys to help manage hypertension?

<p>Diuretics (A)</p> Signup and view all the answers

Which type of drug blocks secretory action in the sympathetic nervous system including alpha 1 blockers and beta blockers?

<p>Antiadrenergics/Sympatholytics (A)</p> Signup and view all the answers

What is the primary action of alpha beta adrenergic blockers like Labetalol (Trandate)?

<p>Block epinephrine action (B)</p> Signup and view all the answers

What is the action of Angiotensin II Receptor Antagonists (ARBs)?

<p>Block angiotensin II receptors to prevent vasoconstriction (A)</p> Signup and view all the answers

Which drug directly inhibits renin action?

<p>Aliskiren (Tekturna) (A)</p> Signup and view all the answers

What is the primary adverse effect of Bile Acid Sequestrants?

<p>Flatulence (A)</p> Signup and view all the answers

Which class of drugs interferes with cholesterol synthesis?

<p>HMG-CoA Reductase Inhibitors (Statins) (A)</p> Signup and view all the answers

What is the primary action of Cholesterol Absorption Inhibitors?

<p>Form a complex with bile (D)</p> Signup and view all the answers

Which drug is indicated for shock by increasing heart rate and force of contraction?

<p>Dobutamine (C)</p> Signup and view all the answers

What is the primary adverse effect of Angiotensin Converting Enzyme Inhibitors (ACE-I)?

<p>Angioedema (B)</p> Signup and view all the answers

Which class of drugs prevents aldosterone binding at the mineralocorticoid receptor?

<p>Aldosterone Blockers (A)</p> Signup and view all the answers

What is the main role of Renin Angiotensin Aldosterone System (RAAS) Inhibitors?

<p>Inhibit renin activity (A)</p> Signup and view all the answers

Which drug of choice for hypertensive crisis should be protected from sunlight to prevent cyanide poisoning?

<p>Nitroprusside (A)</p> Signup and view all the answers

Which adverse effect is NOT associated with Fibric Acid Derivatives?

<p>Severe flushing (B)</p> Signup and view all the answers

Which lipid modifying agent is associated with the adverse effect of joint pains?

<p>Gemfibrozil (Lopid) (C)</p> Signup and view all the answers

Which drug combination product includes Amlodipine?

<p>Amlodipine and Atorvastatin (Caduet) (B)</p> Signup and view all the answers

What is a common adverse effect of Nicotinic Acid Derivatives besides severe flushing?

<p>Tingling (D)</p> Signup and view all the answers

What is a key nursing implication related to liver profile in patients taking Fibric Acid Derivatives?

<p>Decrease saturated fat intake (C)</p> Signup and view all the answers

Flashcards

Ezetimibe adverse effect

Joint pain

Nicotinic Acid Derivatives adverse effect

Allergy

Normal HDL cholesterol level

30 - 75 mg/dL

Fasting required for:

LDL cholesterol blood test

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Vytorin's composition

Ezetimibe and simvastatin combination

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Fibric Acid Derivatives action

Decreases hepatic triglyceride synthesis

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Fibric Acid Derivatives skin effect

Skin rash

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Nicotinic Acid Derivatives primary action

Decreases hepatic triglyceride synthesis

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Diuretics' hypertension action

Balance sodium and water in kidneys

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Central Acting Antiadrenergics action

Blocks sympathetic nervous system secretion

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Peripheral Vasodilators' target

Blood vessels' smooth muscle

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Beta Adrenergic Blockers target

Beta adrenergic receptors

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Peripheral Vasodilators broad action

Block epinephrine and norepinephrine actions

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Statins adverse effect

Muscle pain and cramps

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Bile Acid Sequestrants action

Form complex with bile

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Eplerenone's action

Blocks aldosterone

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Renin inhibitors' action

Inhibit renin

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Antihypotensives' action

Increases heart rate and force

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Dobutamine's action

Mimics epinephrine and norepinephrine

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ACE-I adverse effect

Dry cough

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Peripheral Vasodilators' nursing role

Improve circulation

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Nicotinic Acid + Fibric Acid adverse

Nausea and vomiting

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Ezetimibe primary action

Decrease hepatic triglyceride production

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Gemfibrozil + Fenofibrate Drug Class

Fibric Acid Derivatives

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Antihypertensive Classes for specific situations

Beta-Blockers for hypertension, angina, arrhythmias, hyperthyroidism, panic attacks, and post myocardial infarction

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Alpha blockers indication

Hypertension and Raynaud’s disease

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Study Notes

  • Diuretics are used to manage hypertension by removing sodium and water from the body, with different types including loops, thiazides, and potassium-sparing diuretics.
  • Antiadrenergics/sympatholytics block the secretory action in the sympathetic nervous system, with examples including alpha 2 agonists, alpha 1 blockers, beta blockers, and alpha-beta blockers.
  • Central acting antiadrenergics like alpha 2 agonists include drugs such as Methyldopa, Clonidine, Guanfacine, and Guanabenz.
  • Peripheral acting antiadrenergics like alpha 1 blockers include drugs such as Prazosin, Terazosin, and Doxazosin, used for conditions like hypertension and Raynaud’s disease.
  • Beta adrenergic blockers are used for hypertension, angina, arrhythmias, migraines, hyperthyroidism, panic attacks, and post-myocardial infarction.
  • Calcium channel blockers are indicated for hypertension, angina, arrhythmias, and Raynaud’s disease.
  • Peripheral vasodilators act on the smooth muscle layer of blood vessels, used for severe hypertension and emergencies, with drugs like Diazoxide, Minoxidil, and Nitroprusside being common choices.

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Description

Test your knowledge on antihypertensives, diuretics, antiadrenergics, and central acting antiadrenergic drugs. Learn about indications, mechanisms of action, and common medications used in the treatment of hypertension and related conditions.

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