Pharmacology: Anti-infectives & Penicillin
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Questions and Answers

What is the drug of choice for prophylaxis in non-allergic patients with a history of RHD?

  • Oxacillin
  • Penicillinase-resistant penicillin
  • Penicillin V
  • Penicillin G (correct)

What is the major adverse reaction to penicillin?

  • Nausea and vomiting
  • Tongue inflammation
  • Hypersensitivity reactions (correct)
  • Diarrhea

What is the indication for using Penicillin V?

  • Treatment of bacterial endocarditis
  • Treatment of sexually transmitted diseases
  • Dental situations when an oral narrow spectrum antibiotic is indicated (correct)
  • Prophylaxis in non-allergic patients with a history of RHD

What is the characteristic of Penicillin G?

<p>Poorly absorbed orally (A)</p> Signup and view all the answers

Which type of penicillin is used against penicillinase-resistant staphylococci?

<p>Penicillinase-resistant penicillin (C)</p> Signup and view all the answers

What is the adverse reaction associated with Oxacillin?

<p>Liver toxicity (D)</p> Signup and view all the answers

What is the characteristic of Ampicillin when administered with food?

<p>Decreased absorption (B)</p> Signup and view all the answers

What is the combination of antibiotics used for high-risk cardiac patients?

<p>Ampicillin + Gentamycin (B)</p> Signup and view all the answers

Which antibiotic is a good alternative to penicillin?

<p>Erythromycin (C)</p> Signup and view all the answers

What is the dose of Erythromycin for prophylaxis of patients with RHD?

<p>1gm 1 hr before dental appointment, followed by 500 mg in 6 hours (C)</p> Signup and view all the answers

What is the indication of Carbenicillin-like agents?

<p>For treating infections caused by Pseudomonas and E.Coli strains (A)</p> Signup and view all the answers

What is the dose of Child prophylactic of anti-infectives?

<p>10mg/kg (C)</p> Signup and view all the answers

What is the adverse reaction of Clindamycin?

<p>PMC, superinfection, and osteomyelitis (C)</p> Signup and view all the answers

What is the mechanism of action of Tetracycline?

<p>Interferes with synthesis of bacterial protein (D)</p> Signup and view all the answers

Why should Tetracycline not be used during the last half of pregnancy?

<p>It may affect the fetus's tooth formation (A)</p> Signup and view all the answers

What happens when Tetracycline is administered to infants between 2 months to 8 years old?

<p>It may cause permanent discoloration of the teeth (A)</p> Signup and view all the answers

Which of the following Tetracycline has a unique property of entering the brain in the absence of inflammation?

<p>Minocycline (A)</p> Signup and view all the answers

Which of the following antibiotics is preferred for treating infections in renally compromised patients?

<p>Doxycycline (A)</p> Signup and view all the answers

What is the mechanism of action of cephalosporins?

<p>Inhibition of cell wall synthesis (C)</p> Signup and view all the answers

Which of the following adverse reactions is associated with tetracycline?

<p>Photosensitivity reactions (C)</p> Signup and view all the answers

What is the primary reason for administering cephalosporins parenterally?

<p>Because they are not absorbed from the GI tract (A)</p> Signup and view all the answers

What is a common use of doxycycline in low dosages?

<p>Treating acne (D)</p> Signup and view all the answers

What is a potential interaction of tetracycline with other medications?

<p>Reduced efficacy of oral contraceptives (B)</p> Signup and view all the answers

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