Pharmacology: Anti-infectives & Penicillin
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Questions and Answers

What is the drug of choice for prophylaxis in non-allergic patients with a history of RHD?

  • Oxacillin
  • Penicillinase-resistant penicillin
  • Penicillin V
  • Penicillin G (correct)

    • What is the major adverse reaction to penicillin?

  • Nausea and vomiting
  • Tongue inflammation
  • Hypersensitivity reactions (correct)
  • Diarrhea

    • What is the indication for using Penicillin V?

  • Treatment of bacterial endocarditis
  • Treatment of sexually transmitted diseases
  • Dental situations when an oral narrow spectrum antibiotic is indicated (correct)
  • Prophylaxis in non-allergic patients with a history of RHD

    • What is the characteristic of Penicillin G?

    <p>Poorly absorbed orally</p> Signup and view all the answers

    Which type of penicillin is used against penicillinase-resistant staphylococci?

    <p>Penicillinase-resistant penicillin</p> Signup and view all the answers

    What is the adverse reaction associated with Oxacillin?

    <p>Liver toxicity</p> Signup and view all the answers

    What is the characteristic of Ampicillin when administered with food?

    <p>Decreased absorption</p> Signup and view all the answers

    What is the combination of antibiotics used for high-risk cardiac patients?

    <p>Ampicillin + Gentamycin</p> Signup and view all the answers

    Which antibiotic is a good alternative to penicillin?

    <p>Erythromycin</p> Signup and view all the answers

    What is the dose of Erythromycin for prophylaxis of patients with RHD?

    <p>1gm 1 hr before dental appointment, followed by 500 mg in 6 hours</p> Signup and view all the answers

    What is the indication of Carbenicillin-like agents?

    <p>For treating infections caused by Pseudomonas and E.Coli strains</p> Signup and view all the answers

    What is the dose of Child prophylactic of anti-infectives?

    <p>10mg/kg</p> Signup and view all the answers

    What is the adverse reaction of Clindamycin?

    <p>PMC, superinfection, and osteomyelitis</p> Signup and view all the answers

    What is the mechanism of action of Tetracycline?

    <p>Interferes with synthesis of bacterial protein</p> Signup and view all the answers

    Why should Tetracycline not be used during the last half of pregnancy?

    <p>It may affect the fetus's tooth formation</p> Signup and view all the answers

    What happens when Tetracycline is administered to infants between 2 months to 8 years old?

    <p>It may cause permanent discoloration of the teeth</p> Signup and view all the answers

    Which of the following Tetracycline has a unique property of entering the brain in the absence of inflammation?

    <p>Minocycline</p> Signup and view all the answers

    Which of the following antibiotics is preferred for treating infections in renally compromised patients?

    <p>Doxycycline</p> Signup and view all the answers

    What is the mechanism of action of cephalosporins?

    <p>Inhibition of cell wall synthesis</p> Signup and view all the answers

    Which of the following adverse reactions is associated with tetracycline?

    <p>Photosensitivity reactions</p> Signup and view all the answers

    What is the primary reason for administering cephalosporins parenterally?

    <p>Because they are not absorbed from the GI tract</p> Signup and view all the answers

    What is a common use of doxycycline in low dosages?

    <p>Treating acne</p> Signup and view all the answers

    What is a potential interaction of tetracycline with other medications?

    <p>Reduced efficacy of oral contraceptives</p> Signup and view all the answers

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