Pharmacology 3: Drugs for Hyperlipidemia
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Questions and Answers

Which of the following is a risk factor for coronary heart disease (CHD) according to the text?

  • Regular exercise and a diet containing excess saturated fats
  • Chronic kidney disease (correct)
  • Elevated levels of high-density lipoprotein cholesterol (HDL-C)
  • Low levels of low-density lipoprotein cholesterol (LDL-C)
  • What is the suggested reading for understanding drugs for hyperlipidemia according to the text?

  • Lippincott Pharmacology, 7th ed. 2019, Chapter 22
  • Rang and Dale's Pharmacology
  • Lange Basic and Clinical Pharmacology, 15th ed. 2021, McGraw Hill 2021, Chapter 35 (correct)
  • Goodman & Gilman's The Pharmacological Basis of Therapeutics
  • What is the leading cause of death, as mentioned in the text?

  • Diabetes
  • Elevated cholesterol levels (hyperlipidemia)
  • Coronary heart disease (CHD) (correct)
  • Atherosclerotic cardiovascular disease (ASCVD)
  • What percentage reduction in CHD mortality is expected with appropriate lifestyle and drug therapy?

    <p>30% - 40%</p> Signup and view all the answers

    What does ASCVD include based on the information provided in the text?

    <p>Stroke and peripheral arterial disease</p> Signup and view all the answers

    Which of the following is considered a first-line treatment for patients with elevated risk of atherosclerotic cardiovascular disease (ASCVD)?

    <p>Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors</p> Signup and view all the answers

    What is the therapeutic benefit of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins)?

    <p>Plaque stabilization in arteries</p> Signup and view all the answers

    Which lipoprotein is listed first in decreasing order of atherogenicity according to the given text?

    <p>Low-density lipoprotein (LDL)</p> Signup and view all the answers

    Which drug therapy should be determined based on an assessment of risk for atherosclerotic cardiovascular disease (ASCVD), in conjunction with evaluation of lipoprotein levels?

    <p>Statins</p> Signup and view all the answers

    What is the impact of high levels of high-density lipoprotein cholesterol (HDL-C) as per the given text?

    <p>Decreased risk for CHD</p> Signup and view all the answers

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