Pharmacology 3: Drugs for Hyperlipidemia

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10 Questions

Which of the following is a risk factor for coronary heart disease (CHD) according to the text?

Chronic kidney disease

What is the suggested reading for understanding drugs for hyperlipidemia according to the text?

Lange Basic and Clinical Pharmacology, 15th ed. 2021, McGraw Hill 2021, Chapter 35

What is the leading cause of death, as mentioned in the text?

Coronary heart disease (CHD)

What percentage reduction in CHD mortality is expected with appropriate lifestyle and drug therapy?

30% - 40%

What does ASCVD include based on the information provided in the text?

Stroke and peripheral arterial disease

Which of the following is considered a first-line treatment for patients with elevated risk of atherosclerotic cardiovascular disease (ASCVD)?

Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors

What is the therapeutic benefit of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins)?

Plaque stabilization in arteries

Which lipoprotein is listed first in decreasing order of atherogenicity according to the given text?

Low-density lipoprotein (LDL)

Which drug therapy should be determined based on an assessment of risk for atherosclerotic cardiovascular disease (ASCVD), in conjunction with evaluation of lipoprotein levels?

Statins

What is the impact of high levels of high-density lipoprotein cholesterol (HDL-C) as per the given text?

Decreased risk for CHD

This quiz covers the drugs used for treating hyperlipidemia, focusing on their mechanisms of action and clinical applications. The content is based on the suggested reading from Lippincott Pharmacology and Lange Basic and Clinical Pharmacology.

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