10 Questions
What is a benefit of using LMWH over unfractionated heparin?
More predictable pharmacokinetics
Why is dose adjustment required for LMWH in patients with renal failure?
It is excreted by the kidneys
What did a systematic review and meta-analysis find about preoperative pharmacoprophylaxis and VTE incidence?
40% reduction in the odds of VTE
What complication is LMWH specifically noted to have reduced compared to unfractionated heparin?
Heparin-induced thrombocytopaenia (HIT)
Why is LMWH the preferred agent of choice in many countries, including the UK?
More cost-effective than unfractionated heparin
What is a reason for low-molecular-weight heparin (LMWH) being the preferred agent of choice in many countries, including the UK?
More predictable pharmacokinetics and reduced complications like heparin-induced thrombocytopaenia (HIT)
What did a systematic review and meta-analysis find about the efficacy of preoperative pharmacoprophylaxis (unfractionated heparin and/or LMWH) on the incidence of VTE following major gynaecologic and gynaecology oncological procedures?
40% reduction in the odds of VTE when preoperative pharmacoprophylaxis is given versus no preoperative pharmacoprophylaxi
Why does low-molecular-weight heparin (LMWH) require dose adjustment in patients with renal failure?
It is excreted by the kidneys and has a long half-life
What did a systematic review and meta-analysis find about the efficacy of low-molecular-weight heparin (LMWH) compared to unfractionated heparin in the reduction of VTE?
LMWH was shown to be as effective as unfractionated heparin in the reduction of VTE
What is a benefit of using low-molecular-weight heparin (LMWH) over unfractionated heparin?
More cost-effective and once-daily dosing
Test your knowledge of pharmacological thromboprophylaxis with this quiz. Explore topics such as low-molecular-weight heparin (LMWH) and its effectiveness in reducing VTE, along with dose adjustments in patients with renal failure. ACCP guidance and recommendations for prophylaxis will also be covered.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
