Pharmacological Manipulation of Cardiac and Vascular Function
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Questions and Answers

Which of the following drug classes is considered a first-line choice for the treatment of hypertension according to the NICE ACD rule?

  • Thiazide Diuretics (correct)
  • Antidepressants
  • Anticoagulants
  • Antihistamines

What is a significant characteristic of hypertension described in the text?

  • Highly symptomatic at a diastolic blood pressure (DBP) below 95 mmHg
  • Direct mechanism associated with cancer development
  • It is commonly known as the 'silent killer' (correct)
  • Closely linked to vitamin deficiencies

Which of the following drug classes is not commonly used in the treatment of heart failure?

  • Antibiotics (correct)
  • ACE Inhibitors
  • Digitalis
  • Aldosterone Antagonist

What is the main reason for heart failure according to the text?

<p>Inability of the heart to pump blood effectively (C)</p> Signup and view all the answers

Among the listed drug classes, which one directly influences smooth muscle contraction mechanisms?

<p>Ca2+ Channel Blockers (C)</p> Signup and view all the answers

How does hypertension compare to cancer in terms of mortality according to the text?

<p>Hypertension kills twice as many people as cancer (C)</p> Signup and view all the answers

What percentage of hypertension cases fall under 'Primary Hypertension'?

<p>90% (D)</p> Signup and view all the answers

Which endocrine disease is NOT listed as a cause of 'Secondary Hypertension'?

<p>Addison's disease (B)</p> Signup and view all the answers

What is the risk associated with increasing Diastolic Blood Pressure (DBP) by 10 mmHg?

<p>It doubles the risk of heart attack and stroke. (C)</p> Signup and view all the answers

What was the average follow-up period for patients in the 'Hypertension Optimal Treatment, 1998' intervention trial?

<p>3.8 years (A)</p> Signup and view all the answers

Which factor was shown to have the lowest incidence of major cardiovascular events in the 'Hypertension Optimal Treatment, 1998' trial?

<p>Diastolic Blood Pressure (DBP) &lt; 83 mmHg (D)</p> Signup and view all the answers

Which disease is associated with a tumor of the adrenal medulla?

<p>Phaeochromocytoma (A)</p> Signup and view all the answers

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