Pharmacological Manipulation of Cardiac and Vascular Function
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Questions and Answers

Which of the following drug classes is considered a first-line choice for the treatment of hypertension according to the NICE ACD rule?

  • Thiazide Diuretics (correct)
  • Antidepressants
  • Anticoagulants
  • Antihistamines
  • What is a significant characteristic of hypertension described in the text?

  • Highly symptomatic at a diastolic blood pressure (DBP) below 95 mmHg
  • Direct mechanism associated with cancer development
  • It is commonly known as the 'silent killer' (correct)
  • Closely linked to vitamin deficiencies
  • Which of the following drug classes is not commonly used in the treatment of heart failure?

  • Antibiotics (correct)
  • ACE Inhibitors
  • Digitalis
  • Aldosterone Antagonist
  • What is the main reason for heart failure according to the text?

    <p>Inability of the heart to pump blood effectively</p> Signup and view all the answers

    Among the listed drug classes, which one directly influences smooth muscle contraction mechanisms?

    <p>Ca2+ Channel Blockers</p> Signup and view all the answers

    How does hypertension compare to cancer in terms of mortality according to the text?

    <p>Hypertension kills twice as many people as cancer</p> Signup and view all the answers

    What percentage of hypertension cases fall under 'Primary Hypertension'?

    <p>90%</p> Signup and view all the answers

    Which endocrine disease is NOT listed as a cause of 'Secondary Hypertension'?

    <p>Addison's disease</p> Signup and view all the answers

    What is the risk associated with increasing Diastolic Blood Pressure (DBP) by 10 mmHg?

    <p>It doubles the risk of heart attack and stroke.</p> Signup and view all the answers

    What was the average follow-up period for patients in the 'Hypertension Optimal Treatment, 1998' intervention trial?

    <p>3.8 years</p> Signup and view all the answers

    Which factor was shown to have the lowest incidence of major cardiovascular events in the 'Hypertension Optimal Treatment, 1998' trial?

    <p>Diastolic Blood Pressure (DBP) &lt; 83 mmHg</p> Signup and view all the answers

    Which disease is associated with a tumor of the adrenal medulla?

    <p>Phaeochromocytoma</p> Signup and view all the answers

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