Pharmacokinetics: Routes and Drug Distribution

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10 Questions

Which enzyme is the most abundant in drug metabolism?

CYP3A4

Which drug is an example of a prodrug?

Levodopa

Which drug is incapable of becoming ionized?

Digoxin

Which drug has a high first-pass effect?

Propranolol

Which drug is uniformly distributed in body water?

Ethanol

Which drug has a permanently ionized form?

Heparin

Which drug exhibits a high first-pass effect?

Propranolol

Which drug is an example of a prodrug?

Levodopa

Which enzyme is involved in Phase I reactions of drug metabolism?

Cytochrome P-450 (CYP-450)

'Warfarin' exhibits which characteristic in terms of apparent volume of distribution (aVd)?

Low aVd (e.g., 8L)

Test your knowledge of drug administration routes, pH and ionization of drugs, first-pass metabolism, and drug distribution patterns in the body.

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