Pharmacokinetics Quiz - Drug Absorption Concepts

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

Which pharmacokinetic process involves the movement of drugs from the site of administration to circulating fluids?

  • Excretion
  • Distribution
  • Absorption (correct)
  • Metabolism

What best describes how molecules typically move during diffusion or passive transport?

  • Against an electrochemical gradient
  • From an area of low concentration to high concentration
  • Involving active energy expenditure
  • From an area of high concentration to low concentration (correct)

In which environment is aspirin primarily absorbed due to its nonionized form?

  • Alkaline environment
  • High lipid concentration
  • Acidic environment (correct)
  • Neutral environment

Which factor does NOT affect drug absorption?

<p>Age of the patient (A)</p> Signup and view all the answers

What is the bioavailability percentage of lidocaine and why is it affected?

<p>35% due to destruction in gastric acid and liver metabolism (A)</p> Signup and view all the answers

Cotransport in active transport refers to which of the following?

<p>Simultaneous movement of multiple chemicals across a membrane (D)</p> Signup and view all the answers

What physical property significantly influences the distribution of medications throughout the body?

<p>Amount of blood flow to body tissues (C)</p> Signup and view all the answers

What represents the greatest barrier for many drugs in the body?

<p>Membrane crossing obstacles (C)</p> Signup and view all the answers

Why are acidic drugs typically best absorbed in acidic environments?

<p>They exist in a nonionized form allowing easier absorption (D)</p> Signup and view all the answers

Which factor does NOT affect the bioavailability of a drug?

<p>Patient's age (B)</p> Signup and view all the answers

Flashcards

Pharmacokinetics

The study of how drugs move through the body.

Absorption

The movement of a drug from the site of administration into the bloodstream.

Distribution

The process of a drug spreading throughout the body.

Metabolism

The breakdown of drugs by the body.

Signup and view all the flashcards

Excretion

The removal of drugs and their metabolites from the body.

Signup and view all the flashcards

Active Transport

Movement of drugs against a concentration gradient using energy.

Signup and view all the flashcards

Passive Transport

Movement of drugs from high to low concentration without energy.

Signup and view all the flashcards

Drug Formulation

The physical form of a drug, impacting its absorption.

Signup and view all the flashcards

Route of Admin.

Method a drug is administered (e.g., oral, IV).

Signup and view all the flashcards

Plasma Membranes

Thin layers that separate cells and tissues.

Signup and view all the flashcards

Drug Absorption

The process by which a drug moves from its site of administration into the bloodstream.

Signup and view all the flashcards

Ionization of Drugs (in stomach)

Aspirin, a weak acid, is nonionized in the acidic stomach, allowing good absorption.

Signup and view all the flashcards

Ionization of Drugs (in Small Intestine)

In the alkaline small intestine, aspirin becomes ionized, reducing absorption.

Signup and view all the flashcards

pH and Drug Absorption

The acidity (pH) of a location greatly affects a drug's ability to get absorbed.

Signup and view all the flashcards

Drug-drug/Food-drug Interactions

Interactions between different drugs or food substances can alter drug absorption rates.

Signup and view all the flashcards

Bioavailability

The portion of a drug that reaches the systemic circulation (blood) unchanged after taking it.

Signup and view all the flashcards

First-pass Hepatic Metabolism

The process where a drug is metabolized by the liver after absorption, reducing the amount that reaches the systemic circulation.

Signup and view all the flashcards

Distribution of Medications

The process of carrying drugs throughout the body.

Signup and view all the flashcards

Drug Blood Flow

The degree of blood flow to tissues directly correlates with the rate of drug distribution.

Signup and view all the flashcards

Tissue Affinity

Certain tissues have a higher attraction for particular medications, influencing distribution.

Signup and view all the flashcards

Related Documents

Lecture 2 Pharmacokinatics PDF

More Like This

Use Quizgecko on...
Browser
Browser