Pharmacokinetics of Nicotine - DIMT BS PHARM-401
18 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary mechanism of action of nicotine at low doses?

  • Ganglionic stimulation by depolarization (correct)
  • Central nervous system depression
  • Parasympathetic ganglia inhibition
  • Ganglionic blockade

What is a therapeutic effect of nicotine on the central nervous system?

  • Increased appetite
  • Improved attention and learning (correct)
  • Cardiovascular disease
  • Respiratory paralysis

What is a potential adverse effect of high doses of nicotine?

  • Cardiovascular disease
  • Respiratory paralysis and severe hypotension (correct)
  • Appetite stimulation
  • Central nervous system stimulation

What is an effect of nicotine on the peripheral nervous system?

<p>Stimulation of parasympathetic ganglia (D)</p> Signup and view all the answers

What is a potential risk factor associated with nicotine use?

<p>Lung and cardiovascular disease (B)</p> Signup and view all the answers

What is the effect of nicotine on appetite?

<p>Appetite suppression (B)</p> Signup and view all the answers

Which of the following mechanisms of action is NOT associated with methylxanthines?

<p>Translocation of extracellular potassium (B)</p> Signup and view all the answers

What is the effect of caffeine on the cardiovascular system at high doses?

<p>Positive inotropic and chronotropic effects (C)</p> Signup and view all the answers

How do methylxanthines distribute in the body?

<p>They are distributed throughout the body, including the brain (B)</p> Signup and view all the answers

What is a common adverse effect of methylxanthines at low doses?

<p>Insomnia (C)</p> Signup and view all the answers

What is the primary pathway for the metabolism of methylxanthines in the liver?

<p>CYPIA2 pathway (D)</p> Signup and view all the answers

What is the effect of caffeine on mental alertness at a dose of 100-200mg?

<p>Decrease in fatigue and increased mental alertness (B)</p> Signup and view all the answers

What is the primary mechanism of action of cocaine?

<p>Blockade of the reuptake of the monoamines into the presynaptic terminals (B)</p> Signup and view all the answers

What is the effect of nicotine on the gastrointestinal tract at higher doses?

<p>Cessation of activity due to blockage of parasympathetic ganglia (B)</p> Signup and view all the answers

How is nicotine absorbed into the body?

<p>Due to its high lipid solubility (B)</p> Signup and view all the answers

What is a common side effect of nicotine intake?

<p>Increased heart rate and blood pressure (A)</p> Signup and view all the answers

What is the effect of chronic cocaine intake on dopamine levels?

<p>Depletion of dopamine (B)</p> Signup and view all the answers

What is a significant consequence of cigarette smoking on drug metabolism?

<p>Increased metabolism of certain drugs (B)</p> Signup and view all the answers

More Like This

Nicotine
44 questions

Nicotine

BriskOnyx1786 avatar
BriskOnyx1786
Nicotine Pharmacology Quiz
18 questions

Nicotine Pharmacology Quiz

RejoicingConsonance avatar
RejoicingConsonance
Psychopharmacology Week 6: Nicotine
10 questions
Use Quizgecko on...
Browser
Browser