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Pharmacokinetics of Nicotine - DIMT BS PHARM-401

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Pharmacokinetics of Nicotine - DIMT BS PHARM-401

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Questions and Answers

What is the primary mechanism of action of nicotine at low doses?

Ganglionic stimulation by depolarization (correct)

Central nervous system depression

Parasympathetic ganglia inhibition

Ganglionic blockade

What is a therapeutic effect of nicotine on the central nervous system?

Increased appetite

Improved attention and learning (correct)

Cardiovascular disease

Respiratory paralysis

What is a potential adverse effect of high doses of nicotine?

Cardiovascular disease

Respiratory paralysis and severe hypotension (correct)

Appetite stimulation

Central nervous system stimulation

What is an effect of nicotine on the peripheral nervous system?

Stimulation of parasympathetic ganglia Signup and view all the answers

What is a potential risk factor associated with nicotine use?

Lung and cardiovascular disease Signup and view all the answers

What is the effect of nicotine on appetite?

Appetite suppression Signup and view all the answers

Which of the following mechanisms of action is NOT associated with methylxanthines?

Translocation of extracellular potassium Signup and view all the answers

What is the effect of caffeine on the cardiovascular system at high doses?

Positive inotropic and chronotropic effects Signup and view all the answers

How do methylxanthines distribute in the body?

They are distributed throughout the body, including the brain Signup and view all the answers

What is a common adverse effect of methylxanthines at low doses?

Insomnia Signup and view all the answers

What is the primary pathway for the metabolism of methylxanthines in the liver?

CYPIA2 pathway Signup and view all the answers

What is the effect of caffeine on mental alertness at a dose of 100-200mg?

Decrease in fatigue and increased mental alertness Signup and view all the answers

What is the primary mechanism of action of cocaine?

Blockade of the reuptake of the monoamines into the presynaptic terminals Signup and view all the answers

What is the effect of nicotine on the gastrointestinal tract at higher doses?

Cessation of activity due to blockage of parasympathetic ganglia Signup and view all the answers

Pharmacokinetics of Nicotine - DIMT BS PHARM-401

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Podcast

Questions and Answers

What is the primary mechanism of action of nicotine at low doses?

What is a therapeutic effect of nicotine on the central nervous system?

What is a potential adverse effect of high doses of nicotine?

What is an effect of nicotine on the peripheral nervous system?

What is a potential risk factor associated with nicotine use?

What is the effect of nicotine on appetite?

Which of the following mechanisms of action is NOT associated with methylxanthines?

What is the effect of caffeine on the cardiovascular system at high doses?

How do methylxanthines distribute in the body?

What is a common adverse effect of methylxanthines at low doses?

What is the primary pathway for the metabolism of methylxanthines in the liver?

What is the effect of caffeine on mental alertness at a dose of 100-200mg?

What is the primary mechanism of action of cocaine?

What is the effect of nicotine on the gastrointestinal tract at higher doses?

How is nicotine absorbed into the body?

What is a common side effect of nicotine intake?

What is the effect of chronic cocaine intake on dopamine levels?

What is a significant consequence of cigarette smoking on drug metabolism?

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