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Questions and Answers
What form of the drug is available for action, metabolism, and excretion?
What form of the drug is available for action, metabolism, and excretion?
- Protein-bound fraction
- Plasma protein-bound fraction
- Bound fraction
- Free and unbound fraction (correct)
Which type of drugs bind mainly to albumin?
Which type of drugs bind mainly to albumin?
- Neutral drugs
- Acidic drugs (correct)
- Neutral and basic drugs
- Basic drugs
What prolongs the duration of action of a drug?
What prolongs the duration of action of a drug?
- Protein binding (correct)
- Distribution
- Metabolism
- Excretion
What must drugs be in order to cross the blood-brain barrier?
What must drugs be in order to cross the blood-brain barrier?
Which barrier allows lipid-soluble unionized drugs to readily cross?
Which barrier allows lipid-soluble unionized drugs to readily cross?
What does volume of distribution describe?
What does volume of distribution describe?
What is the term used to describe the movement of a drug from its site of administration into the bloodstream?
What is the term used to describe the movement of a drug from its site of administration into the bloodstream?
Which route of absorption compensates for first-pass metabolism by ensuring 100% bioavailability?
Which route of absorption compensates for first-pass metabolism by ensuring 100% bioavailability?
What does the term 'enterohepatic circulation' refer to in drug metabolism?
What does the term 'enterohepatic circulation' refer to in drug metabolism?
How can first-pass metabolism be compensated for with some drugs?
How can first-pass metabolism be compensated for with some drugs?
Which route of drug administration may result in low bioavailability due to metabolism in the gut wall and liver before systemic circulation?
Which route of drug administration may result in low bioavailability due to metabolism in the gut wall and liver before systemic circulation?
What term describes the dispersion of drugs from the bloodstream to other tissues and their site of action?
What term describes the dispersion of drugs from the bloodstream to other tissues and their site of action?
What is the definition of pharmacokinetics?
What is the definition of pharmacokinetics?
Which route of drug administration involves passing the drug through the cheeks?
Which route of drug administration involves passing the drug through the cheeks?
What is pharmacology primarily concerned with?
What is pharmacology primarily concerned with?
Which of the following is NOT a route of enteral drug administration?
Which of the following is NOT a route of enteral drug administration?
What is the role of metabolism in pharmacokinetics?
What is the role of metabolism in pharmacokinetics?
Which barrier must a drug pass through during enteral drug administration?
Which barrier must a drug pass through during enteral drug administration?
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