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Pharmacokinetics, Dynamics, Drug Interactions, and Genomics Lecture

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Pharmacokinetics, Dynamics, Drug Interactions, and Genomics Lecture

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Questions and Answers

What is pharmacokinetics primarily concerned with?

Drug action at sites of action

Drug movement throughout the body (correct)

Drug passage across cell membranes

Drug metabolism and excretion

Which process is responsible for transporting a wide variety of drugs out of the cells?

Direct penetration of the membrane

P-glycoprotein system (correct)

Liver elimination process

Channels and pores transport systems

What is the primary determining factor for a drug's movement through the body?

Transport systems of the drug

Size of the drug

Lipid solubility of the drug (correct)

Ionization of the drug

What term is used to describe the accumulation of acidic drugs on the alkaline side, and basic drugs on the acidic side?

Ion trapping Signup and view all the answers

What is another term for drug metabolism?

Biotransformation Signup and view all the answers

In which type of environment are weak organic acids best absorbed?

Acidic environment Signup and view all the answers

Which process involves the drug's movement from the blood into the interstitial space of tissues and then into cells?

Distribution Signup and view all the answers

Which processes together determine the concentration of the drug at sites of action?

Metabolism and excretion Signup and view all the answers

What does absorption refer to in the context of drug movement?

Movement of a drug from its site of administration into the blood Signup and view all the answers

In pharmacokinetics, what does absorption refer to?

Drug movement from the site of administration into the blood Signup and view all the answers