Pharmacokinetics, Dynamics, Drug Interactions, and Genomics Lecture
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Questions and Answers

What is pharmacokinetics primarily concerned with?

  • Drug action at sites of action
  • Drug movement throughout the body (correct)
  • Drug passage across cell membranes
  • Drug metabolism and excretion

Which process is responsible for transporting a wide variety of drugs out of the cells?

  • Direct penetration of the membrane
  • P-glycoprotein system (correct)
  • Liver elimination process
  • Channels and pores transport systems

What is the primary determining factor for a drug's movement through the body?

  • Transport systems of the drug
  • Size of the drug
  • Lipid solubility of the drug (correct)
  • Ionization of the drug

What term is used to describe the accumulation of acidic drugs on the alkaline side, and basic drugs on the acidic side?

<p>Ion trapping (D)</p> Signup and view all the answers

What is another term for drug metabolism?

<p>Biotransformation (D)</p> Signup and view all the answers

In which type of environment are weak organic acids best absorbed?

<p>Acidic environment (B)</p> Signup and view all the answers

Which process involves the drug's movement from the blood into the interstitial space of tissues and then into cells?

<p>Distribution (D)</p> Signup and view all the answers

Which processes together determine the concentration of the drug at sites of action?

<p>Metabolism and excretion (D)</p> Signup and view all the answers

What does absorption refer to in the context of drug movement?

<p>Movement of a drug from its site of administration into the blood (C)</p> Signup and view all the answers

In pharmacokinetics, what does absorption refer to?

<p>Drug movement from the site of administration into the blood (A)</p> Signup and view all the answers

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