Pharmacokinetics and Terminology
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Questions and Answers

An LPN is caring for a patient with a peripherally inserted central catheter (PICC) line. Which of the following actions is within the LPN's scope of practice, according to the provided guidelines?

  • Maintaining the central venous infusion of approved fluids and checking the dressing. (correct)
  • Initiating the administration of chemotherapeutic agents through the PICC line.
  • Discontinuing the PICC line based on the patient's improved condition.
  • Administering a rapid intravenous bolus of medication.

A physician orders vancomycin $1$ gram IV q12h for a patient with a MRSA infection. The patient's creatinine level is elevated. What is the most appropriate initial action for the nurse?

  • Check peak and trough levels after the first dose.
  • Administer the vancomycin as prescribed, as it is a standard dose for MRSA.
  • Immediately contact the physician to question the drug dose.
  • Consult with the pharmacist to determine if the elevated creatinine affects drug dosing. (correct)

An LPN is working under the supervision of an RN in a long-term care facility. Which of the following intravenous fluids can the LPN initiate via a peripheral route, according to the state's Board of Nursing?

  • 5% Dextrose in 0.45% Sodium Chloride (D5 1/2 NS). (correct)
  • Total Parenteral Nutrition (TPN).
  • Albumin 25%.
  • Packed Red Blood Cells (PRBCs).

A patient receiving IV antibiotics has orders for peak and trough levels. When should the nurse obtain the trough level?

<p>30 minutes before the next antibiotic dose is administered. (D)</p> Signup and view all the answers

An LPN is preparing to administer an intravenous piggyback (IVPB) medication. Which of the following medications, according to the Board of Nursing guidelines, is the LPN permitted to administer via IVPB?

<p>Antiemetics. (B)</p> Signup and view all the answers

A drug that initiates a physiological change in the body is best described as which of the following?

<p>An agonist (C)</p> Signup and view all the answers

After a drug is processed by the body, the amount of the drug that is available for use is referred to as:

<p>Bioavailability (B)</p> Signup and view all the answers

In the context of IV fluid administration, what does the abbreviation 'KVO' signify?

<p>Keep vein open (D)</p> Signup and view all the answers

When administering multiple IV medications, staggering the administration times addresses which potential issue?

<p>Preventing chemical incompatibilities (C)</p> Signup and view all the answers

Which of the following best describes 'therapeutic drug administration'?

<p>Treating an existing problem with a drug to produce a desired effect (B)</p> Signup and view all the answers

Which of the following is the MOST critical nursing action if a visible precipitate is observed in an IV solution during administration?

<p>Immediately stop the infusion (C)</p> Signup and view all the answers

A patient receiving an IV antibiotic develops a sudden onset of hives, difficulty breathing, and a drop in blood pressure. This is most likely indicative of what condition?

<p>Anaphylaxis (B)</p> Signup and view all the answers

A medication order reads, 'Administer 1 gram of Ceftriaxone IVPB every 12 hours.' Which of the following rights of IV administration does 'IVPB' directly relate to?

<p>Right Route (B)</p> Signup and view all the answers

A patient is prescribed two drugs that, when combined, result in a greater therapeutic effect than either drug would produce alone. This is an example of what type of drug interaction?

<p>Synergistic (B)</p> Signup and view all the answers

A patient reports experiencing ringing in their ears (tinnitus) after starting a new medication. This could be a sign of which type of organ-specific toxicity?

<p>Ototoxicity (B)</p> Signup and view all the answers

A patient is receiving an antibiotic via continuous IV infusion. Why is it important to draw serum drug levels?

<p>To maintain correct therapeutic drug levels (C)</p> Signup and view all the answers

Which of the following best describes chemical incompatibilities between IV drugs?

<p>A reaction that alters the drug's potency, which may not be visible (B)</p> Signup and view all the answers

Before administering an IV antibiotic, a nurse checks the IV site and notes that there is no backflow and resistance is met when flushing. What is the MOST appropriate nursing action?

<p>Discontinue the IV and insert a new IV at a different site (C)</p> Signup and view all the answers

A patient develops a secondary infection during antibiotic treatment that is resistant to the initial antibiotic. This is best described as which of the following?

<p>Superinfection (B)</p> Signup and view all the answers

A patient receiving vancomycin IV develops redness and itching after 15 minutes of the infusion. What is MOST appropriate initial nursing action?

<p>Stop the infusion (A)</p> Signup and view all the answers

Flashcards

Pre-Drug Administration Tests

Evaluates kidney and liver function to ensure safe drug administration and prevent toxicity.

Peak and Trough Levels

Measure drug concentration at its highest (peak) and lowest (trough) levels to maintain therapeutic range and avoid toxicity.

State Board of Nursing

LPNs must follow the regulations and guidelines set by their state's Board of Nursing.

Common IV Flush Solutions

Saline (NS) or Dextrose (D5W)

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LPN IV Supervision

LPNs can perform IV therapy under the supervision of a healthcare professional who is physically present at the facility.

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Pharmacokinetics

The study of drug actions within the body, including absorption, distribution, bioavailability, and drug action.

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Absorption (Drugs)

The passage of a drug into the blood and tissues after the drug formulation is broken down.

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Distribution (Drugs)

How the drug is transported to target tissues, usually through the bloodstream.

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Bioavailability

The amount of drug available for use in the body after it has been processed.

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Target Cells

Specific sites where a drug is intended to have a therapeutic effect.

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Antagonist (Drug)

A drug that opposes the action of another drug.

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Agonist (Drug)

A drug that initiates a physiological change in the body.

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Diagnostic Testing (Drugs)

Using drugs for sensitivity testing to determine effective treatments for infections.

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Prophylactic Drug Administration

Administering drugs to prevent potential problems, like antibiotics before surgery.

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Therapeutic Drug Administration

Administering drugs to treat an existing problem, aiming to produce a desired effect.

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Rights of IV Administration

Ensuring the right patient, time, drug, dose, route, and documentation.

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Therapeutic Incompatibilities

Undesirable effects resulting from two or more drugs being given concurrently.

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Anaphylaxis

Severe, life-threatening hypersensitivity reaction requiring immediate respiratory status monitoring.

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Synergistic Drug Interactions

Drug interactions producing effects greater than the sum of their individual actions (1 + 1 = 4).

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Superinfection

A secondary infection by a different pathogen, often resistant to the initial treatment.

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Study Notes

No updates are needed. All the information provided is already present in the existing notes.

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Description

Overview of pharmacokinetics including absorption, distribution, bioavailability, and drug action. Key terminology includes target cells, antagonists, agonists, CBC, IVPB, KVO, and LR. Understanding these principles is crucial for effective drug administration and patient care.

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