5 Questions
What is the general focus of pharmacokinetics?
Absorption, distribution, metabolism, and excretion of drugs
Which factor largely determines the rate of drug absorption?
Lipid solubility
What does bioavailability refer to in pharmacokinetics?
Fraction of dose that becomes available at the action site
What does drug distribution refer to in pharmacokinetics?
Movement of drugs in the bloodstream
Which route is preferred for drug administration due to sterility and convenience?
Oral (gut)
Study Notes
Pharmacokinetics
- The general focus of pharmacokinetics is on the movement of drugs within the body, including absorption, distribution, metabolism, and elimination.
Drug Absorption
- The rate of drug absorption is largely determined by the rate of dissolution of the drug in the gastrointestinal tract.
Bioavailability
- Bioavailability refers to the extent to which the active drug ingredient becomes available to the target site in the body.
- It is a measure of the fraction of an administered dose of a drug that reaches the systemic circulation.
Drug Distribution
- Drug distribution refers to the dissemination of the drug throughout the body, including the movement of the drug from the systemic circulation into tissues and organs.
Route of Drug Administration
- The intravenous route is preferred for drug administration due to its sterility and convenience.
- This route allows for rapid and complete absorption of the drug, as it avoids the need for absorption from the gastrointestinal tract.
Test your knowledge of pharmacokinetics and pharmacodynamics with this quiz covering general principles of pharmacology, drug handling by the body, drug action, and the specific pharmacokinetics of ophthalmic drugs.
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