5 Questions
What are the constituents of Gentian root?
Seco-iridoid bitter principles, bitter principles, and sugar constituents
What changes occur during the fermentation of Gentian root?
Color changes from white to yellowish brown, odor changes from odorless to distinctive characteristic odor, and taste becomes pleasant sweet then becomes bitter
What is the mechanism of action of bitters like Gentian root?
Stimulates appetite and digestion via a general stimulation of the digestive juices, promotes production of saliva, gastric juices and bile, and accelerates the emptying of the stomach
What are the constituents of Rhizoma Rhei?
Anthraquinone glycosides
What is the primary use of Gentian root?
It is used as a bitter tonic
Study Notes
Gentian Root
- Constituents of Gentian root include glycosides (gentiopicroside, gentisin, and trigonelline), alkaloids (gentianine and gentianidine), and bitter principles (secoiridoid glycosides)
Fermentation of Gentian Root
- During fermentation, the glycosides are broken down into aglycones, which increases the bitterness of the root
- This process enhances the bioavailability and absorption of the active compounds
Mechanism of Action of Bitters like Gentian Root
- Bitters like Gentian root stimulate bitter taste receptors on the tongue, activating the digestive system and increasing saliva production
- This, in turn, stimulates the release of digestive enzymes, gastric acid, and bile, improving digestion and nutrient absorption
Rhizoma Rhei (Rhubarb Root)
- Constituents of Rhizoma Rhei include anthraquinone glycosides (sennosides), flavonoids, and polyphenols
- Rhizoma Rhei is used as a laxative and for its anti-inflammatory properties
Primary Use of Gentian Root
- Gentian root is primarily used as a digestive stimulant, appetite stimulant, and to relieve indigestion and flatulence
Test your knowledge of subterranean organs and the botanical origin and constituents of radix gentianae in Pharmacognosy II. Learn about the dried fermented root and rhizome of Gentiana lutea and its bitter principles.
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