Pharmacognosy: Adjuvants and Excipients

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10 Questions

What is the primary function of adjuvants in pharmaceutical formulations?

To enhance or modify the effect of a pharmacologically active substance

Which of the following is NOT a function of excipients in pharmaceutical formulations?

To reduce the side effects of the drug

What is the primary function of pharmaceutical packaging?

To protect the drug product from light, moisture, and contamination

What is the primary goal of drug delivery systems?

To control the release and absorption of the drug

What is the primary goal of cosmetic formulation?

To enhance appearance and skin health

Which of the following is an example of a drug delivery system?

Transdermal patch

What is the primary function of a lubricant in pharmaceutical formulations?

To reduce friction during the manufacturing process

Which of the following is an example of an excipient?

Lactose

What is the primary function of a coating in pharmaceutical packaging?

To protect the drug product from light, moisture, and contamination

Which of the following is a key component of cosmetic formulation?

Preservatives

Study Notes

Pharmacognosy

Adjuvants

  • Substances that enhance or modify the effect of a drug or other pharmacologically active substance
  • Examples: preservatives, antioxidants, and pH adjusters
  • Functions:
    • Enhance bioavailability
    • Improve stability
    • Modify release rates
    • Enhance patient compliance

Excipients

  • Inactive substances used in pharmaceutical formulations
  • Functions:
    • Fillers (e.g., lactose, starch)
    • Binders (e.g., starch, gum arabic)
    • Lubricants (e.g., magnesium stearate)
    • Glidants (e.g., silicon dioxide)
    • Coatings (e.g., shellac, wax)

Drug Delivery Systems

  • Methods or formulations that control the release and absorption of a drug
  • Examples:
    • Controlled-release tablets or capsules
    • Transdermal patches
    • Liposomes
    • Nanoparticles
  • Goals:
    • Improve bioavailability
    • Reduce side effects
    • Enhance patient compliance
    • Target specific tissues or cells

Pharmaceutical Packaging

  • Materials and containers used to protect and preserve pharmaceutical products
  • Functions:
    • Protect from light, moisture, and contamination
    • Maintain potency and stability
    • Ensure product identity and authenticity
    • Provide patient instructions and warnings
  • Types:
    • Glass or plastic bottles
    • Blister packs
    • Ampoules
    • Prefilled syringes

Cosmetic Formulation

  • Combination of ingredients to create a cosmetic product
  • Key components:
    • Active ingredients (e.g., retinol, vitamin C)
    • Inactive ingredients (e.g., emollients, thickeners)
    • Preservatives (e.g., parabens, phenoxyethanol)
    • pH adjusters and buffers
  • Goals:
    • Enhance appearance and skin health
    • Provide moisturizing and protective effects
    • Minimize irritation and allergic reactions

Pharmacognosy

Adjuvants

  • Enhance or modify the effect of a drug or other pharmacologically active substance
  • Examples include preservatives, antioxidants, and pH adjusters
  • Functions: enhance bioavailability, improve stability, modify release rates, and enhance patient compliance

Excipients

  • Inactive substances used in pharmaceutical formulations
  • Functions include:
    • Fillers (e.g., lactose, starch)
    • Binders (e.g., starch, gum arabic)
    • Lubricants (e.g., magnesium stearate)
    • Glidants (e.g., silicon dioxide)
    • Coatings (e.g., shellac, wax)

Drug Delivery Systems

  • Methods or formulations that control the release and absorption of a drug
  • Examples include:
    • Controlled-release tablets or capsules
    • Transdermal patches
    • Liposomes
    • Nanoparticles
  • Goals: improve bioavailability, reduce side effects, enhance patient compliance, and target specific tissues or cells

Pharmaceutical Packaging

  • Materials and containers used to protect and preserve pharmaceutical products
  • Functions include:
    • Protect from light, moisture, and contamination
    • Maintain potency and stability
    • Ensure product identity and authenticity
    • Provide patient instructions and warnings
  • Types: glass or plastic bottles, blister packs, ampoules, and prefilled syringes

Cosmetic Formulation

  • Combination of ingredients to create a cosmetic product
  • Key components include:
    • Active ingredients (e.g., retinol, vitamin C)
    • Inactive ingredients (e.g., emollients, thickeners)
    • Preservatives (e.g., parabens, phenoxyethanol)
    • pH adjusters and buffers
  • Goals: enhance appearance and skin health, provide moisturizing and protective effects, and minimize irritation and allergic reactions

Learn about the role of adjuvants and excipients in pharmaceutical formulations, including their functions and examples.

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