Pharmacodynamics of Contact Laxatives
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Questions and Answers

Which of the following is a cause of constipation?

  • Taking opioid medication (correct)
  • Eating a balanced diet
  • Drinking plenty of water
  • Engaging in regular physical activity

    • What is the main function of bulk-forming laxatives?

  • To soften the stool
  • To increase peristalsis in the GI tract
  • To absorb excess fluid from the stool (correct)
  • To stimulate bowel movements

    • Which natural resource is commonly used as an osmotic laxative?

  • Plantago psyllium (psyllii semen/psyllium)
  • Angustifolia (manna)
  • Linum usitatissimum (lini semen/linseed)
  • Fraxinus ornus (manna) (correct)

    • Which chemical constituents are responsible for the effect of stimulant laxatives?

    <p>Anthrones</p> Signup and view all the answers

    What is the main function of stimulant laxatives?

    <p>Reducing transit time</p> Signup and view all the answers

    Which natural resource is commonly used as a stimulant laxative?

    <p>Cassia Senna</p> Signup and view all the answers

    What is the potential side effect of long-term use of stimulant laxatives?

    <p>Pseudomelanosis coli</p> Signup and view all the answers

    Which group of medicinal products may enhance the loss of potassium when used concomitantly with the medication described in the text?

    <p>Diuretics</p> Signup and view all the answers

    Why is the use of this medication contraindicated during pregnancy?

    <p>It may pose a genotoxic risk</p> Signup and view all the answers

    What are the possible undesirable effects of this medication?

    <p>Hypersensitivity reactions and gastrointestinal disorders</p> Signup and view all the answers

    What is the main pharmacodynamic effect of this medication?

    <p>Increase in the leakiness of the tight junctions in the colon</p> Signup and view all the answers

    Which of the following is a pharmacodynamic effect of sennosides?

    <p>Increased leakiness of tight junctions</p> Signup and view all the answers

    What happens to hydroxyanthracene derivatives in food when consumed at high doses?

    <p>They can cause genotoxicity</p> Signup and view all the answers

    Which of the following is a possible side effect of Frangula alnus (Frangula)?

    <p>Colic</p> Signup and view all the answers

    What is the recommended duration of use for aloe barbadensis (aloe)?

    <p>Not to be used for more than 1 week</p> Signup and view all the answers

    Which of the following is a characteristic of bulk-forming laxatives?

    <p>They pass through the GI tract unchanged.</p> Signup and view all the answers

    Which natural resource is commonly used as a bulk-forming laxative?

    <p>Linum usitatissimum (lini semen/linseed)</p> Signup and view all the answers

    What is the main effect of osmotic laxatives?

    <p>They absorb fluid from the lumen.</p> Signup and view all the answers

    Which of the following is a potential side effect of long-term use of stimulant laxatives?

    <p>Pseudomelanosis coli</p> Signup and view all the answers

    What is the recommended duration of use for stimulant laxatives?

    <p>1 week</p> Signup and view all the answers

    Which natural resource is commonly used as a stimulant laxative?

    <p>Cassia Senna (Senna fructus)</p> Signup and view all the answers

    What is the main function of stimulant laxatives?

    <p>Increasing peristalsis of the colon</p> Signup and view all the answers

    Which of the following is a possible side effect of aloe barbadensis (aloe)?

    <p>Hypokalaemia</p> Signup and view all the answers

    What is the main pharmacokinetic property of sennosides?

    <p>They are excreted in bile</p> Signup and view all the answers

    Which of the following is a contraindication for the use of the medication described in the text?

    <p>Intestinal obstruction</p> Signup and view all the answers

    What is the main mechanism of action of Frangula alnus (Frangula)?

    <p>Stimulation of the motility of the large intestine</p> Signup and view all the answers

    Which of the following is a potential adverse effect of long-term use of anthranoid-containing medicinal products?

    <p>Hypokalaemia</p> Signup and view all the answers

    Which group of medicinal products may enhance the loss of potassium when used concomitantly with anthranoid-containing medicinal products?

    <p>Diuretics</p> Signup and view all the answers

    Why is the use of anthranoid-containing medicinal products contraindicated during lactation?

    <p>They can pass into breast milk and harm the baby</p> Signup and view all the answers

    What is the main pharmacodynamic effect of contact laxatives?

    <p>Inhibition of water and electrolyte absorption in the colon</p> Signup and view all the answers

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