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Pharmacodynamics Lectures Quiz

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Questions and Answers

How does dimercaprol (BAL) function in the body?

Neutralizes gastric acid secretion

Increases the permeability of bacterial plasma membrane

Chelates arsenic, mercury, and copper (correct)

Inhibits protein synthesis in bacteria by binding to 50S ribosomal subunit

What is the mechanism of action of protamine?

Increases the permeability of bacterial plasma membrane

Antagonizes heparin by its alkaline and positive charge (correct)

Inhibits protein synthesis in bacteria by binding to 50S ribosomal subunit

Chelates calcium, lead, and digitalis

What is the primary function of EDTA in pharmacodynamics?

Inhibits protein synthesis in bacteria by binding to 30S ribosomal subunit

Increases the permeability of bacterial plasma membrane

Neutralizes gastric acid secretion

Chelates calcium, lead, and digitalis (correct)

What is the role of penicillamine in pharmacodynamics?

<p>Chelates copper and used in treatment of Wilson’s disease</p> Signup and view all the answers

What is the action of polymixins and amphotericin B on bacteria?

<p>Increase the permeability of bacterial plasma membrane</p> Signup and view all the answers

Study Notes

Chelating Agents

Dimercaprol (BAL) is a chelating agent used to treat heavy metal poisoning by binding to metals, such as arsenic, mercury, and lead, and forming a complex that can be excreted from the body.

Anticoagulant Reversal

Protamine is a drug used to reverse the effects of heparin, a blood thinner, by binding to it and neutralizing its anticoagulant activity.

Chelating Agents

EDTA (ethylenediaminetetraacetic acid) is a chelating agent used to treat hypercalcemia and heavy metal poisoning by binding to calcium and heavy metals, such as lead, and removing them from the body.

Rheumatoid Arthritis Treatment

Penicillamine is a chelating agent used to treat rheumatoid arthritis by reducing inflammation and joint damage, possibly by removing excess copper from the body.

Antibacterial Agents

Polymyxins are antibacterial agents that disrupt the outer membrane of Gram-negative bacteria, ultimately leading to bacterial cell death.
Amphotericin B is an antifungal agent that forms pores in the fungal cell membrane, allowing ions to leak out and ultimately leading to fungal cell death.

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Description

Test your knowledge of pharmacodynamics with this quiz based on lectures by Dr. Ghada Samy. Learn about the biochemical and pharmacological effects of drugs, their mechanisms of action, and how drugs produce their effects through different mechanisms.