Pharmacodynamics: Drug Action vs Drug Effect
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Questions and Answers

What is the mechanism whereby drugs exert their effect on the body?

  • Metabolism
  • Pharmacokinetics
  • Pharmacodynamics (correct)
  • Drug administration
  • Which of the following best describes the difference between drug action and drug effect?

  • Action is the therapeutic outcome, while effect is the mechanism of action.
  • Effect is the alteration of the condition that brings about action.
  • Action and effect are terms that can be used interchangeably.
  • Action precedes effect; effect is the result of action. (correct)
  • Which type of drugs work through physical mechanisms?

  • Drugs acting on receptors
  • Chelating agents
  • Enzyme inhibitors
  • Osmotic laxatives (correct)
  • What class of drugs primarily act on biological catalysts in the body?

    <p>Enzyme inhibitors</p> Signup and view all the answers

    In pharmacology, what remains unchanged at the conclusion of a reaction involving enzymes?

    <p>The enzymes</p> Signup and view all the answers

    Which type of drugs are relatively or completely specific for certain substrates?

    <p>Drugs acting on receptors</p> Signup and view all the answers

    When two drugs with the same effect are given together, producing a drug effect that is greater in magnitude than the sum of the individual effects of the two drugs, it is an example of:

    <p>Synergism</p> Signup and view all the answers

    Which of the following drug combinations results in increased sedation or CNS depression?

    <p>Alcohol + Chloral hydrate</p> Signup and view all the answers

    Potentiation occurs when:

    <p>One drug enhances the effect of another drug without any impact of its own</p> Signup and view all the answers

    Which drug combination results in increased hypoglycemic effects?

    <p>Alcohol + Chlorpropamide</p> Signup and view all the answers

    What type of drug interaction is seen when one drug, lacking an effect of its own, increases the effect of another active drug?

    <p>Potentiation</p> Signup and view all the answers

    Which drug combination causes increased negative inotropic & chronotropic effects?

    <p>Flecainide + Verapamil</p> Signup and view all the answers

    Which theory postulates a complementary relationship between the drug molecule and its active site?

    <p>Induced-Fit Theory</p> Signup and view all the answers

    In receptor theories, what is the function of an antagonist drug?

    <p>Counteract an agonist</p> Signup and view all the answers

    What attribute of a drug is the measure of the equilibrium constant of the drug-receptor interaction in classical occupation theory?

    <p>Affinity</p> Signup and view all the answers

    Which type of drug can elicit some but not a maximal effect and antagonize an agonist according to the occupation theory?

    <p>Partial Agonist</p> Signup and view all the answers

    What is the main requirement for a drug to have its maximum effect according to Clark's Hypothesis?

    <p>Both affinity to receptor and occupancy of receptors</p> Signup and view all the answers

    Which theory emphasizes that the drug molecule must specifically 'fit into' a receptor to induce a response?

    <p>Lock and Key Theory</p> Signup and view all the answers

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