Pharmacodynamics: Drug Action vs Drug Effect
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Questions and Answers

What is the mechanism whereby drugs exert their effect on the body?

  • Metabolism
  • Pharmacokinetics
  • Pharmacodynamics (correct)
  • Drug administration

Which of the following best describes the difference between drug action and drug effect?

  • Action is the therapeutic outcome, while effect is the mechanism of action.
  • Effect is the alteration of the condition that brings about action.
  • Action and effect are terms that can be used interchangeably.
  • Action precedes effect; effect is the result of action. (correct)

Which type of drugs work through physical mechanisms?

  • Drugs acting on receptors
  • Chelating agents
  • Enzyme inhibitors
  • Osmotic laxatives (correct)

What class of drugs primarily act on biological catalysts in the body?

<p>Enzyme inhibitors (A)</p> Signup and view all the answers

In pharmacology, what remains unchanged at the conclusion of a reaction involving enzymes?

<p>The enzymes (D)</p> Signup and view all the answers

Which type of drugs are relatively or completely specific for certain substrates?

<p>Drugs acting on receptors (C)</p> Signup and view all the answers

When two drugs with the same effect are given together, producing a drug effect that is greater in magnitude than the sum of the individual effects of the two drugs, it is an example of:

<p>Synergism (C)</p> Signup and view all the answers

Which of the following drug combinations results in increased sedation or CNS depression?

<p>Alcohol + Chloral hydrate (A)</p> Signup and view all the answers

Potentiation occurs when:

<p>One drug enhances the effect of another drug without any impact of its own (A)</p> Signup and view all the answers

Which drug combination results in increased hypoglycemic effects?

<p>Alcohol + Chlorpropamide (A)</p> Signup and view all the answers

What type of drug interaction is seen when one drug, lacking an effect of its own, increases the effect of another active drug?

<p>Potentiation (A)</p> Signup and view all the answers

Which drug combination causes increased negative inotropic & chronotropic effects?

<p>Flecainide + Verapamil (D)</p> Signup and view all the answers

Which theory postulates a complementary relationship between the drug molecule and its active site?

<p>Induced-Fit Theory (C)</p> Signup and view all the answers

In receptor theories, what is the function of an antagonist drug?

<p>Counteract an agonist (C)</p> Signup and view all the answers

What attribute of a drug is the measure of the equilibrium constant of the drug-receptor interaction in classical occupation theory?

<p>Affinity (C)</p> Signup and view all the answers

Which type of drug can elicit some but not a maximal effect and antagonize an agonist according to the occupation theory?

<p>Partial Agonist (C)</p> Signup and view all the answers

What is the main requirement for a drug to have its maximum effect according to Clark's Hypothesis?

<p>Both affinity to receptor and occupancy of receptors (A)</p> Signup and view all the answers

Which theory emphasizes that the drug molecule must specifically 'fit into' a receptor to induce a response?

<p>Lock and Key Theory (D)</p> Signup and view all the answers

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