Podcast
Questions and Answers
What type of bond is the weakest among the following?
What type of bond is the weakest among the following?
Which type of molecule forms bonds with a receptor to elicit a biological response?
Which type of molecule forms bonds with a receptor to elicit a biological response?
What pertains to the strength of a drug-receptor complex?
What pertains to the strength of a drug-receptor complex?
Which type of receptor is located on the cell membrane?
Which type of receptor is located on the cell membrane?
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What type of molecule interacts with a receptor to produce a therapeutic response?
What type of molecule interacts with a receptor to produce a therapeutic response?
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What type of molecule binds to a receptor site to block or depress the biological response?
What type of molecule binds to a receptor site to block or depress the biological response?
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What is the purpose of the color-coding system used in the unit-dose system?
What is the purpose of the color-coding system used in the unit-dose system?
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How does the unit-dose system benefit nursing personnel?
How does the unit-dose system benefit nursing personnel?
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Why does the pharmacist have a profile of all medications for each patient in the unit-dose system?
Why does the pharmacist have a profile of all medications for each patient in the unit-dose system?
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What benefit does unit-dose packaging provide in terms of drug counting?
What benefit does unit-dose packaging provide in terms of drug counting?
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In the unit-dose system, whose responsibility is it to check drugs and calculate dosages?
In the unit-dose system, whose responsibility is it to check drugs and calculate dosages?
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Why is there less waste and misappropriation in the unit-dose system?
Why is there less waste and misappropriation in the unit-dose system?
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What is the official name of a drug known as?
What is the official name of a drug known as?
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What term is derived from the Greek for 'poison' and 'study'?
What term is derived from the Greek for 'poison' and 'study'?
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What does pharmacodynamics focus on?
What does pharmacodynamics focus on?
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What does drug action refer to?
What does drug action refer to?
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Which type of chemical bond is part of the Ligand-Receptor relationship in drug action?
Which type of chemical bond is part of the Ligand-Receptor relationship in drug action?
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What is the main focus of Pharmacokinetics?
What is the main focus of Pharmacokinetics?
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What information is included on each package in a unit-dose drug distribution system?
What information is included on each package in a unit-dose drug distribution system?
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Where are individual packages dispensed in a unit-dose system typically stored for each patient?
Where are individual packages dispensed in a unit-dose system typically stored for each patient?
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How is the long-term care unit-dose system different from the acute care unit-dose system?
How is the long-term care unit-dose system different from the acute care unit-dose system?
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What does the pharmacist do in the long-term care unit-dose system?
What does the pharmacist do in the long-term care unit-dose system?
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Where are the individualized containers or envelopes sometimes stored in long-term care facilities?
Where are the individualized containers or envelopes sometimes stored in long-term care facilities?
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What does a unit-dose drug distribution system use to fill each dose requirement as it is ordered?
What does a unit-dose drug distribution system use to fill each dose requirement as it is ordered?
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What physiological processes does pharmacokinetics involve?
What physiological processes does pharmacokinetics involve?
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What can happen when probenecid is mixed with ampicillin in the same syringe?
What can happen when probenecid is mixed with ampicillin in the same syringe?
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Which pharmacokinetic parameter refers to the time required for the drug concentration to decrease by half?
Which pharmacokinetic parameter refers to the time required for the drug concentration to decrease by half?
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Which process involves the movement of a drug from its site of administration into the systemic circulation?
Which process involves the movement of a drug from its site of administration into the systemic circulation?
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What happens when ampicillin is mixed with gentamicin?
What happens when ampicillin is mixed with gentamicin?
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What does distribution in pharmacokinetics refer to?
What does distribution in pharmacokinetics refer to?
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Study Notes
Types of Bonds and Molecular Interactions
- Weakest bond type is ionic bonds; they are generally less strong compared to covalent or hydrogen bonds.
- Agonist molecules form bonds with receptors to trigger biological responses.
Drug-Receptor Complex and Receptors
- Strength of a drug-receptor complex is determined by factors like affinity and efficacy.
- Cell membrane receptors include G-protein coupled receptors (GPCRs) and ion channel receptors.
Therapeutic Responses and Blockers
- Agonist molecules interact with receptors to yield therapeutic effects.
- Antagonists bind to receptor sites to inhibit or block biological responses.
Unit-Dose System Purpose and Benefits
- Color-coding in unit-dose systems helps with easy identification and organization of medications.
- Benefits to nursing personnel include reduced medication errors and improved patient safety.
Pharmacist Roles in Medication Profiles
- Pharmacists maintain patient medication profiles in unit-dose systems for tracking and avoiding interactions.
- Unit-dose packaging simplifies drug counting, reducing the chance of error.
Responsibilities and Waste Reduction
- Nurses are responsible for verifying medications and calculating dosages in the unit-dose system.
- The unit-dose system minimizes waste and misappropriation due to precise dosage packaging.
Official Drug Terminology and Pharmacological Terms
- Official name of a drug is known as its generic name.
- The term "pharmacology" derives from Greek words meaning 'poison' and 'study.'
Key Focus Areas in Pharmacology
- Pharmacodynamics studies drug effects and mechanisms of action.
- Drug action describes the interaction between a drug and its biological target.
Chemical Bonds and Pharmacology
- Ligand-receptor relationships in drug actions primarily involve non-covalent bonds.
- Pharmacokinetics focuses on drug absorption, distribution, metabolism, and excretion (ADME).
Unit-Dose Drug Distribution
- Each unit-dose package includes essential information such as dosage and administration instructions.
- Individual unit doses are typically stored in specific locations designated for each patient.
Differences in Long-Term vs. Acute Care
- Long-term care unit-dose systems differ from acute care by offering greater customization for chronic medications.
- Pharmacists in long-term care coordinate medication management tailored to residents' needs.
Storage and Filling in Long-Term Care
- Individualized containers for medications may be stored in a designated area to enhance accessibility.
- Unit-dose systems utilize a just-in-time approach for filling each required dose as orders are placed.
Pharmacokinetics Processes and Interactions
- Key physiological processes involved in pharmacokinetics are absorption, distribution, metabolism, and excretion.
- Mixing probenecid with ampicillin can lead to altered drug effectiveness or toxicity if administered improperly.
- The pharmacokinetic half-life refers to the duration needed for drug concentration in the bloodstream to reduce by 50%.
Drug Mixing and Distribution
- The process of absorption involves drug movement from the administration site into systemic circulation.
- Mixing ampicillin with gentamicin can result in drug incompatibility and therapeutic failure.
- Drug distribution in pharmacokinetics refers to how a drug disperses throughout the body's compartments after absorption.
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Description
Learn about drug nomenclature, including chemical name, generic name, and brand name. Understand the importance of each in pharmacology and drug identification.
