Podcast
Questions and Answers
Which aspect of pharmaceutics is MOST directly concerned with how a drug is absorbed, distributed, metabolized, and eliminated by the body?
Which aspect of pharmaceutics is MOST directly concerned with how a drug is absorbed, distributed, metabolized, and eliminated by the body?
- Biopharmaceutics (correct)
- Quality Control and Assurance
- Stability Testing
- Dosage Form Design
A pharmaceutical company is developing a new tablet formulation for an existing drug. Which preformulation study would be MOST critical in determining if the drug can be effectively made into a tablet?
A pharmaceutical company is developing a new tablet formulation for an existing drug. Which preformulation study would be MOST critical in determining if the drug can be effectively made into a tablet?
- Microbial growth studies
- Taste-masking evaluations
- Color and odor assessment
- Particle size and powder flow properties (correct)
A drug is known to undergo significant degradation in the presence of moisture. Which excipient would be LEAST suitable for use in a tablet formulation of this drug?
A drug is known to undergo significant degradation in the presence of moisture. Which excipient would be LEAST suitable for use in a tablet formulation of this drug?
- Calcium phosphate dibasic
- Anhydrous lactose
- Microcrystalline cellulose (correct)
- Magnesium stearate
A drug is intended to treat a localized skin infection. Which dosage form would be MOST appropriate to minimize systemic side effects?
A drug is intended to treat a localized skin infection. Which dosage form would be MOST appropriate to minimize systemic side effects?
Which route of administration bypasses first-pass metabolism, leading to higher bioavailability and rapid drug effect?
Which route of administration bypasses first-pass metabolism, leading to higher bioavailability and rapid drug effect?
A pharmaceutical manufacturer discovers that a batch of tablets does not meet content uniformity specifications. Under which guidelines would this be investigated?
A pharmaceutical manufacturer discovers that a batch of tablets does not meet content uniformity specifications. Under which guidelines would this be investigated?
A drug is designed to release its medication over an extended period after oral administration. What type of formulation is this?
A drug is designed to release its medication over an extended period after oral administration. What type of formulation is this?
Which factor is LEAST likely to affect the stability of a drug product?
Which factor is LEAST likely to affect the stability of a drug product?
A generic drug manufacturer must demonstrate that its product is bioequivalent to the reference listed drug. Which application is required for this approval?
A generic drug manufacturer must demonstrate that its product is bioequivalent to the reference listed drug. Which application is required for this approval?
During the scale-up of a tablet manufacturing process, what is the primary goal of process validation?
During the scale-up of a tablet manufacturing process, what is the primary goal of process validation?
What is the MOST important consideration when designing a controlled-release oral dosage form?
What is the MOST important consideration when designing a controlled-release oral dosage form?
A pharmacist notices a change in the appearance of a medication, such as a change in color or the formation of a precipitate. What type of pharmaceutics study can help determine if the medication is still safe and effective to use?
A pharmacist notices a change in the appearance of a medication, such as a change in color or the formation of a precipitate. What type of pharmaceutics study can help determine if the medication is still safe and effective to use?
What is the appropriate term to describe the rate and extent to which an active drug ingredient is absorbed from a drug product and becomes available at the site of action?
What is the appropriate term to describe the rate and extent to which an active drug ingredient is absorbed from a drug product and becomes available at the site of action?
Which of the following is NOT a primary goal of drug targeting?
Which of the following is NOT a primary goal of drug targeting?
If a drug is poorly soluble in water, which formulation strategy might be employed to improve its oral bioavailability?
If a drug is poorly soluble in water, which formulation strategy might be employed to improve its oral bioavailability?
Flashcards
Pharmaceutics
Pharmaceutics
The science of turning drugs into safe and effective medications.
Preformulation Studies
Preformulation Studies
Characterizing drug & excipient properties for stable dosage forms.
Formulation Development
Formulation Development
Combining APIs and excipients into a suitable form for administration.
Dosage Form Design
Dosage Form Design
Signup and view all the flashcards
Manufacturing
Manufacturing
Signup and view all the flashcards
Biopharmaceutics
Biopharmaceutics
Signup and view all the flashcards
Bioavailability
Bioavailability
Signup and view all the flashcards
Good Manufacturing Practice (GMP)
Good Manufacturing Practice (GMP)
Signup and view all the flashcards
Pharmacokinetics
Pharmacokinetics
Signup and view all the flashcards
Pharmacodynamics
Pharmacodynamics
Signup and view all the flashcards
Parenteral Route
Parenteral Route
Signup and view all the flashcards
Immediate-Release Formulation
Immediate-Release Formulation
Signup and view all the flashcards
Extended-Release Formulation
Extended-Release Formulation
Signup and view all the flashcards
Stability Testing
Stability Testing
Signup and view all the flashcards
Dissolution rate
Dissolution rate
Signup and view all the flashcards
Study Notes
It appears the provided text is identical to the existing notes. Therefore, no new information can be added.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Pharmaceutics is the science of turning drugs into safe and effective medications through dosage form design. Key areas include drug design, preformulation studies, and formulation development. It focuses on the manufacture, stability, and effectiveness of pharmaceutical dosage forms.
