5 Questions
Describe the importance of Na2CO3 in the synthesis of ethyl acetate.
Na2CO3 is used to neutralize the excess acetic acid and adjust the pH of the reaction mixture, which helps in the separation of ethyl acetate from the reaction mixture.
Explain the role of C.H2SO4 in the synthesis of ethyl acetate.
C.H2SO4 is used as a catalyst to facilitate the esterification reaction between ethanol and acetic acid, leading to the formation of ethyl acetate.
What is the significance of NaOH in the synthesis of iodoform?
NaOH plays a crucial role in oxidizing ethanol to acetaldehyde, which is essential for the formation of iodoform.
Why does nitration of toluene preferentially occur in the para position?
Nitration of toluene preferentially occurs in the para position due to steric hindrance and resonance stabilization, leading to the formation of para-nitrotoluene as the main product.
Where does further nitration of p-nitrotoluene occur, and why?
Further nitration of p-nitrotoluene occurs in the ortho position due to the presence of an electron-donating group, which activates the ortho position for electrophilic substitution.
Test your knowledge of pharmaceutical synthesis with questions about the synthesis of ethyl acetate and iodoform. Understand the reasons behind the use of C.H2SO4 and Na2CO3 in ethylacetate synthesis and the role of NaOH in iodoform formation.
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