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Explain the challenges of cooling a reactor to low temperatures on an industrial scale during pharmaceutical manufacturing.
Explain the challenges of cooling a reactor to low temperatures on an industrial scale during pharmaceutical manufacturing.
The cost and viscosity increase make cooling to low temperatures complicated, leading to added costs, difficult mixing, and non-homogeneous reactions. Lower temperatures can also result in crusting of reagents, intermediates, and byproducts, impacting the purity of the product.
How can different stoichiometric ratios of reagents affect the products formed during pharmaceutical manufacturing on an industrial scale?
How can different stoichiometric ratios of reagents affect the products formed during pharmaceutical manufacturing on an industrial scale?
Different stoichiometric ratios of reagents can result in different ratios of products formed. Adding a large amount of reagent A to reagent B may lead to imbalance and premature reactions, affecting the subsequent products.
What are some unit operations involved in the process of pharmaceutical drug manufacturing?
What are some unit operations involved in the process of pharmaceutical drug manufacturing?
Unit operations involved in pharmaceutical drug manufacturing include milling, granulation, coating, tablet pressing, and others.
What are the scale-up considerations in pharmaceutical manufacturing related to cooling?
What are the scale-up considerations in pharmaceutical manufacturing related to cooling?
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How does the process of drug manufacturing on an industrial scale involve considerations of stoichiometry?
How does the process of drug manufacturing on an industrial scale involve considerations of stoichiometry?
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