Pharmaceutical Lecture: Liquid Dosage Forms
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Questions and Answers

What is the upper size limit for colloidal dispersions?

  • 2 μm
  • 5 μm
  • 1 μm (correct)
  • 1 nm
  • What term is used for compounds that accumulate at the boundary between two phases?

  • Suspensions
  • Emulsions
  • Amphiphilic (correct)
  • Aerosols
  • What type of dispersions frequently exceeds the size of 1 μm?

  • Colloidal dispersions
  • Aerosols
  • Surfactant
  • Emulsions (correct)
  • What is the characteristic feature of surface-active compounds in their chemical structure?

    <p>Amphipathy</p> Signup and view all the answers

    What enables the dispersion of insoluble particles in the form of a suspension?

    <p>Adsorption of surfactants on solid surfaces</p> Signup and view all the answers

    True or false: Emulsions and suspensions are examples of colloidal dispersions?

    <p>True</p> Signup and view all the answers

    True or false: The upper size limit for colloidal dispersions is 1 μm?

    <p>False</p> Signup and view all the answers

    True or false: Surface-active compounds are characterized by having only one distinct region in their chemical structure?

    <p>False</p> Signup and view all the answers

    True or false: The existence of two distinct regions in a molecule is referred to as amphipathy?

    <p>True</p> Signup and view all the answers

    True or false: Aerosols are considered coarse dispersions with droplet size typically exceeding 1 μm?

    <p>True</p> Signup and view all the answers

    Which of the following is a cause of arrhythmias related to the abnormal rate of discharge in pacemaker cells?

    <p>Enhanced automaticity of the ventricles</p> Signup and view all the answers

    Which ion channels are targeted by most antiarrhythmic agents to suppress automaticity?

    <p>Sodium (Na+)</p> Signup and view all the answers

    Why is it useful to organize arrhythmias into groups according to anatomic site of the abnormality?

    <p>To simplify the understanding of a large group of disorders</p> Signup and view all the answers

    Which heart structure normally sets the pace of contraction for the myocardium?

    <p>SA node</p> Signup and view all the answers

    What type of drugs are predominantly used to manage chronic heart failure and arrhythmias?

    <p>Antiarrhythmic drugs</p> Signup and view all the answers

    Study Notes

    Colloidal Dispersions

    • The upper size limit for colloidal dispersions is not 1 μm, but rather 1-10 nm to 1 μm.
    • Surface-active compounds, also known as surfactants, are characterized by having two distinct regions in their chemical structure: a hydrophobic (water-repelling) tail and a hydrophilic (water-attracting) head.
    • Emulsions and suspensions are examples of colloidal dispersions.
    • The existence of two distinct regions in a molecule is referred to as amphipathy.
    • Aerosols are not considered colloidal dispersions, but rather coarse dispersions with droplet size typically exceeding 1 μm.

    Arrhythmias

    • Arrhythmias related to the abnormal rate of discharge in pacemaker cells can be caused by abnormal ion channel function.
    • Most antiarrhythmic agents target ion channels to suppress automaticity.
    • Organizing arrhythmias into groups according to anatomic site of the abnormality is useful because it helps to identify the underlying cause of the arrhythmia and guide treatment.
    • The sinoatrial (SA) node, located in the right atrium, normally sets the pace of contraction for the myocardium.
    • Beta blockers, along with other antiarrhythmic agents, are predominantly used to manage chronic heart failure and arrhythmias.

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    Test your knowledge about liquid dosage forms, specifically suspensions and emulsions. Learn about dispersed systems and the components of disperse phases.

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