19 Questions
What is the term for the composition at the eutectic point in the lead-silver system?
Eutectic composition
At the eutectic point, how many phases coexist in the lead-silver system?
Three phases
In a three-component system, what does a point on any side of the triangle represent?
Mixture of two components
What do relative quantities of components in a mixture in a three-component system relate to?
Relative distance from sides of the triangle
Which physicochemical properties determine a drug's capacity to undergo phase transitions post-administration?
Drug's melting point and solubility
In drug delivery, what is the first phase after administration?
Release into physiological fluids
What is required after precipitation of a drug from solution?
Dissolution
Which factor influences the rate of dissolution of drugs administered in solid phase?
Physiological fluid pH
In which type of formulation is melting point crucial to consider?
Topical medicines
What is important in the formulation of medicines that release vapor for inhalation?
API release at room temperature
Which drug administration route involves gas absorption of APIs into the bloodstream?
Airways
Why is dissolution into physiological fluids important for drugs administered in solid phase?
To facilitate absorption
What defines the number of components in a system?
The chemically distinct constituents
In a vaporization curve, what does the curve OA represent?
Equilibrium between water and vapor
When two immiscible liquids like benzene and water are combined, how many phases are formed?
Two
What characterizes a two component system?
Two independent components present in a heterogeneous system
In the context of drug formulation, what does the degree of freedom represent?
Number of variables needed to define equilibrium
What does a T-C diagram represent in a phase diagram?
Temperature against composition
How many forms of equilibria exist in a single-component (C=1) system such as water?
Three forms
Test your knowledge on pharmaceutical formulation processes including precipitation and vaporization. Learn about factors leading to drug precipitation from solution and the importance of vaporization in medical formulations. Challenge yourself with questions on drug dissolution and inhalable medicines.
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