15 Questions
When preparing a pharmaceutical solution, what is a crucial consideration to ensure the final product is safe for use?
The toxicity of the chemicals involved
In pharmaceutical manufacturing, what is an important aspect to consider when selecting chemicals for production?
The availability of the chemical
During the preparation of a pharmaceutical solution, what is a critical factor in maintaining the drug's potency?
The stability of the drug and buffer on aging
In the production of pharmaceutical solutions, what is an important consideration to minimize the risk of contamination?
The sterility of the final solution
What is an essential consideration in pharmaceutical manufacturing to ensure the production of a high-quality product?
The freedom from toxicity of the chemicals used
Why is a borate buffer not suitable for a solution that will be administered orally or parenterally?
Due to its toxic effects
What is a common application of isotonic solutions?
In the preparation of pharmaceutical solutions
What is a consequence of freezing point depression in a solution?
A decrease in the freezing point
What is the primary consideration in the preparation of a solution for parenteral administration?
The toxicity of the buffer used
What is the relationship between osmotic pressure and tonicity?
Osmotic pressure determines tonicity
What is the consequence of cells being subjected to osmotic pressures?
Cells swell and can be lysed
What is the purpose of using 'isotonic solutions' in biology and pharmaceutics?
To avoid the effects of osmotic pressures
What is the term used to describe the ability of a solution to exert osmotic pressure?
Tonicity
What is the result of using a hypotonic solution in a pharmaceutical application?
Cells swell and can be lysed
Why are isotonic solutions important in pharmaceutical applications?
They help to preserve the structure of cells
Study Notes
Considerations for Pharmaceutical Solutions
- Chemical availability, sterilization of final solution, drug and buffer stability over time, material cost, and toxicity freedom should be considered.
- Cell swelling and lysis can occur as a result of osmotic pressures.
Isotonic Solutions in Biology and Pharmaceutics
- Isotonic solutions are used in biology and pharmaceutics to prevent osmotic pressure effects.
- Borate buffer is toxic and cannot be used to stabilize oral or parenteral solutions.
This quiz assesses understanding of key factors to consider when formulating pharmaceuticals, including chemical availability, sterility, stability, cost, and toxicity. It evaluates knowledge of the importance of these factors in ensuring effective and safe drug development.
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