18 Questions
Which of the following can induce polymerization in a pharmaceutical formulation?
Light exposure
What is the primary purpose of using buffers in pharmaceutical compounding?
To maintain the optimal pH for drug stability
What is the benefit of storing pharmaceutical ingredients at a suitable low temperature?
To prevent polymerization of ingredients
Which of the following can be used to prevent polymerization in pharmaceutical compounding?
Suitable vehicle selection
What is the primary concern when combining surfactants with different charges in a pharmaceutical formulation?
Chemical incompatibility reactions
What is the term for the conversion of a drug to its isomer?
Isomerization
What is the primary reason for using hydroalcoholic or alcoholic vehicles in pharmaceutical formulation?
To prevent oxidation of the drug ingredients
What is the primary function of buffers in pharmaceutical formulation?
To adjust the pH of the formulation
Why is it necessary to protect the drug formulation from light?
To prevent degradation of the active ingredients
What is the benefit of selecting a solid dosage form over a solution?
Reduced risk of oxidation of the drug ingredients
Why is it important to store pharmaceutical formulations at a low temperature?
To prevent oxidation and degradation of the drug ingredients
What is the purpose of replacing oxygen with nitrogen inside the container?
To prevent oxidation of the drug ingredients
What is the purpose of adding a thickening agent in liquid preparations containing indiffusible solids?
To obtain an elegant product with uniform dose
Why are wetting agents used in formulations containing insoluble powders?
To enhance the wetting of the powders
What is the consequence of using excess surface active agents in a formulation?
Claying due to deflocculation
How can the insolubility of potent drugs be addressed?
By converting them into salt forms
What happens when a resinous tincture is added to water?
The resin agglomerates forming indiffusible clots
What is the purpose of using polysorbates in parenteral suspensions of corticosteroids and antibiotics?
To act as a wetting agent and prevent claying
Learn about the factors that induce polymerization in pharmaceutical compounding, including light, solvents, pH, and temperature, and understand the preventive measures to prevent polymerization reactions.
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