Pharmaceutical Chemistry Quiz

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Questions and Answers

What is the route of absorption for primary amides of estrone?

Through the skin

Through injection

Through inhalation

Through the oral route (correct)

What is the chemical structure that primary amides of estrone are absorbed through?

R-COOH

R-OH

R-Cl

R-NH-C (correct)

What is the comparison being made in the text?

Between two types of medication

Between two absorption routes

Between two hormone structures

Between primary amides of estrone and carboxylic acid (correct)

What is the focus of the text?

Pharmacokinetics of estrone Signup and view all the answers

What is the other compound being compared to primary amides of estrone?

Carboxylic acid Signup and view all the answers

What is a characteristic of primary medications?

They are broken down into smaller compounds Signup and view all the answers

What is the purpose of using primary medications?

To enhance the absorption of poorly absorbed drugs Signup and view all the answers

Which of the following is an example of a primary medication?

Salazin Signup and view all the answers

What happens to primary medications in the body?

They are broken down into smaller compounds Signup and view all the answers

What is the result of breaking down primary medications?

The formation of smaller compounds, one of which may be the active drug Signup and view all the answers

What is the purpose of the drug if it doesn't act locally in the gastrointestinal tract?

To reach the target site through the blood circulation Signup and view all the answers

What is the barrier that the drug needs to pass through to reach the bloodstream?

Gastrointestinal mucosal membrane Signup and view all the answers

What is the acid that the drug, enalapril, is converted to?

Enalaprilic acid Signup and view all the answers

Why does the drug need to pass through the gastrointestinal mucosal membrane?

To be absorbed into the bloodstream Signup and view all the answers

What is the chemical name of the drug?

N-CH3 Enalapril Signup and view all the answers

What is the chemical formula for the medication chloramphenicol?

C14H12Cl2N2O5 Signup and view all the answers

What is the name of the medication that is an example of a primary amide?

Chloramphenicol Signup and view all the answers

What is the chemical structure of chloramphenicol?

R = H, R' = CO(CH2)2OH Signup and view all the answers

What is the name of the medication that is a palmitate?

Chloramphenicol Palmitate Signup and view all the answers

What is the chemical functional group found in chloramphenicol?

Amide Signup and view all the answers

What is the status of some features?

Unavailable Signup and view all the answers

What action is being performed?

Translating a page Signup and view all the answers

What is the name of the translation service?

Google Translate Signup and view all the answers

What time is mentioned in the text?

8:05 Signup and view all the answers

What question is being asked?

Is this result useful? Signup and view all the answers

Study Notes

Primary Drugs

Primary drugs, such as prodrugs, are converted into smaller compounds, one of which is the active drug.
Prodrugs are used to enhance the absorption of poorly absorbed drugs from the gastrointestinal system.

Absorption of Primary Drugs

Primary drugs, such as esters, are absorbed orally more than carboxylic acid forms, e.g., enalapril: R = CH3, enalaprilic acid: R = H, OH.
Unless the purpose of the drug is to act locally in the gastrointestinal system, it must cross the gastric mucosal barrier to reach the bloodstream and then the target site.

Examples of Primary Drugs

Osalazine and chloramphenicol palmitate are examples of primary drugs.
Chloramphenicol has a molecular weight of 143.

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Description

This quiz covers pharmaceutical chemistry, including chemical structures and names of various medications and their derivatives. Topics include chloramphenicol palmitate and chloramphenicol succinate.