Pharm Made Easy 4.0 Neuro Part 1

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Questions and Answers

What instruction should a nurse include for a client with Alzheimer's disease taking memantine?

  • Increase fluid intake
  • Take the drug with food
  • Avoid taking over-the-counter antacids (correct)
  • Limit physical activity

Which laboratory test requires monitoring for a client prescribed pramipexole for Parkinson's disease?

  • Electrolyte levels
  • Creatinine clearance (correct)
  • Glucose level
  • Liver function tests

What should a client taking dantrolene report as an adverse effect?

Diarrhea

What adverse effect should a client taking valproic acid monitor for?

<p>Jaundice</p> Signup and view all the answers

What instruction should be included for a client taking levodopa/carbidopa?

<p>Change position slowly to prevent orthostatic hypotension</p> Signup and view all the answers

When should a client taking modafinil be instructed to take the drug?

<p>In the morning</p> Signup and view all the answers

What should a client taking baclofen be advised regarding driving?

<p>Avoid driving until the drug's effects are evident</p> Signup and view all the answers

What pharmacologic effect does levodopa/carbidopa have?

<p>Increases available dopamine in the brain</p> Signup and view all the answers

What should a client do to help avoid adverse effects when taking interferon beta-1a?

<p>Premedicate with acetaminophen</p> Signup and view all the answers

What adverse effect should a nurse monitor for in a client receiving methohexital sodium?

<p>Respiratory depression</p> Signup and view all the answers

What can a drug interaction between selegiline and meperidine result in?

<p>Muscle rigidity</p> Signup and view all the answers

What instruction should be given to a client about taking carbamazepine?

<p>Begin taking the drug at a low dosage</p> Signup and view all the answers

What condition is sumatriptan indicated for?

<p>Presence of a migraine headache</p> Signup and view all the answers

What medical history finding indicates a need to withhold memantine?

<p>Cirrhosis</p> Signup and view all the answers

What drug should be available to reverse the effects of fentanyl?

<p>Naloxone (Narcan)</p> Signup and view all the answers

What adverse effects should be monitored in a client taking valproic acid?

<p>Drowsiness, headache, and rash</p> Signup and view all the answers

Where should interferon beta-1a be administered?

<p>In your thigh or upper arm</p> Signup and view all the answers

Which laboratory test requires monitoring for a client on dantrolene?

<p>Liver function</p> Signup and view all the answers

What adverse effect should a client taking amphetamine sulfate monitor for?

<p>Tachycardia</p> Signup and view all the answers

What can result from the interaction between valproic acid and phenytoin?

<p>Phenytoin toxicity</p> Signup and view all the answers

What adverse effect should be monitored in a client starting sumatriptan therapy?

<p>Chest pain</p> Signup and view all the answers

What adverse effect should a nurse monitor in a client taking donepezil?

<p>Nausea</p> Signup and view all the answers

What weight change should be reported by a client taking amphetamine/dextroamphetamine sulfate?

<p>Weight loss of 2.3 kg (5 lb)</p> Signup and view all the answers

What indicates a potential serious adverse effect of interferon beta-1b?

<p>Fatigue</p> Signup and view all the answers

What should the family of a client with Alzheimer's disease know about donepezil?

<p>Avoid the use of NSAIDs for pain</p> Signup and view all the answers

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Study Notes

Memantine

  • Used for Alzheimer's disease; instruct to avoid over-the-counter antacids.
  • Antacids with sodium bicarbonate can increase urine alkalinity, decreasing drug excretion and leading to toxicity.

Pramipexole

  • Prescribed for Parkinson's disease; monitor creatinine clearance.
  • Use cautiously in patients with renal impairment.

Dantrolene

  • Used to treat skeletal muscle spasms; instruct clients to report diarrhea as a potential adverse effect.

Valproic Acid

  • Prescribed for seizure disorders; monitor for jaundice due to the risk of hepatic toxicity.
  • Symptoms of hepatic toxicity include abdominal pain and nausea.

Levodopa/Carbidopa

  • Treats Parkinson's disease; instruct clients to change positions slowly to prevent orthostatic hypotension.

Modafinil

  • Prescribed for narcolepsy; advise clients to take the drug in the morning to align with wakefulness.

Baclofen

  • A muscle relaxant; instruct clients to avoid driving until they understand the drug's effects on them.

Interferon Beta-1a

  • Used for multiple sclerosis; premedicate with acetaminophen to minimize fever, chills, and muscle aches.
  • Administer subcutaneously in the thigh or upper arm.

Methohexital Sodium

  • A short-acting barbiturate; monitor for respiratory depression and ensure mechanical ventilation is available if needed.

Selegiline

  • Used for Parkinson's disease; monitor for muscle rigidity when considering concurrent use of meperidine due to potential interactions.

Carbamazepine

  • Prescribed for seizures; instruct clients to start at a low dosage to minimize adverse effects like visual disturbances and ataxia.

Sumatriptan

  • Indicated for migraine headaches; instruct clients to monitor for chest pain as a potential adverse effect.

Fentanyl

  • Used to reduce pain; naloxone (Narcan) should be available to reverse severe respiratory depression.

Donepezil

  • Used for Alzheimer's disease; monitor for nausea, a common adverse effect. Advise taking with food to lessen stomach upset.

Amphetamine/Dextroamphetamine Sulfate

  • Treats ADHD; report unintended weight loss (e.g., 5 lb) due to decreased appetite.

Drug Interactions

  • Valproic acid can increase blood levels of phenytoin, risking toxicity.
  • Avoid using NSAIDs in conjunction with donepezil due to the risk of gastrointestinal bleeding.

Additional Monitoring

  • Dantrolene requires liver function monitoring.
  • Amphetamine sulfate may lead to tachycardia; clients should report palpitations or chest pain.

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