Pharm D Program (2023/2024) Lecture on Bacterial Cell Wall & Structures
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What is the main aim of the lecture on Bacterial Cell Wall & Structures internal to the cell wall?

  • To discuss the human immune response to bacterial cell walls
  • To explore the effects of antibiotics on the bacterial cell wall
  • To introduce students to the concept of bacterial cell division
  • To provide knowledge about the functions and chemical composition of the cell wall and internal structures in bacterial cells (correct)
  • Which of the following is NOT listed as a structure internal to the bacterial cell wall?

  • Nuclear area (Nucleoid)
  • Ribosomes
  • Cytoplasm
  • Mitochondria (correct)
  • What is the function of the bacterial cell wall?

  • To act as a semi-rigid structure responsible for cell shape (correct)
  • To regulate cellular respiration
  • To synthesize proteins
  • To store genetic material
  • Why is the bacterial cell wall considered essential for viability?

    <p>To protect the fragile plasma membrane and interior of the cell</p> Signup and view all the answers

    What is one of the key roles of the cytoplasmic membrane in bacterial cells?

    <p>Maintaining cell shape and structure</p> Signup and view all the answers

    Which of the following is NOT a structure internal to the bacterial cell wall as mentioned in the lecture?

    <p>Endoplasmic reticulum</p> Signup and view all the answers

    Which bacterial component is responsible for the endotoxic (pyrogenic) effects causing fever and shock?

    <p>Phospholipid called lipid A</p> Signup and view all the answers

    What is the main function of the strong negative charge of the outer membrane?

    <p>Evading phagocytosis and the action of the complement system</p> Signup and view all the answers

    What is the main function of the porins in the outer membrane?

    <p>Both b and c</p> Signup and view all the answers

    What is the main function of the periplasmic space?

    <p>Containing a single peptidoglycan layer and degradative enzymes</p> Signup and view all the answers

    Which of the following molecules can pass through the porins in the outer membrane?

    <p>Nucleotides, disaccharides, peptides, amino acids, vitamins and iron</p> Signup and view all the answers

    Which of the following is NOT a function of the outer membrane?

    <p>Sustaining the metabolism of the cell</p> Signup and view all the answers

    What is the main function of bacterial endospores?

    <p>To protect the bacterial cell against unfavorable conditions</p> Signup and view all the answers

    What is the process of endospore formation within a vegetative (parent) cell called?

    <p>Sporulation</p> Signup and view all the answers

    Which of the following is NOT a characteristic of the endospore core?

    <p>Contains a large amount of calcium and dipicolinic acid</p> Signup and view all the answers

    How long can bacterial spores resist boiling, compared to vegetative cells?

    <p>Spores can resist boiling for 2 hours, while vegetative cells die at 80°C</p> Signup and view all the answers

    What happens during the germination of bacterial spores?

    <p>The spore wall breaks down, and the spore core rehydrates and resumes metabolic activity</p> Signup and view all the answers

    Which of the following statements about bacterial endospores is NOT correct?

    <p>Endospores are a reproductive process, as one spore gives rise to one bacterium</p> Signup and view all the answers

    What is the main structural difference between Gram-positive and Gram-negative cell walls?

    <p>Presence of an outer membrane</p> Signup and view all the answers

    Which type of cell wall has a higher percentage of peptidoglycan content?

    <p>Gram-positive</p> Signup and view all the answers

    What is the function of teichoic acids in the cell wall?

    <p>Assist in cross-linking peptidoglycan chains</p> Signup and view all the answers

    Which component is more abundant in the cytoplasmic membrane of prokaryotes?

    <p>Phospholipids</p> Signup and view all the answers

    What is the role of an outer membrane in Gram-negative cell walls?

    <p>Provide protection against certain antibiotics</p> Signup and view all the answers

    Which type of cell wall has a higher degree of cross-linking in its peptidoglycan?

    <p>Gram-positive</p> Signup and view all the answers

    Which of the following is NOT a reason for the importance of the bacterial cell wall?

    <p>It contains unique components found in other organisms.</p> Signup and view all the answers

    What is the basic structure of the bacterial cell wall?

    <p>A macromolecular network of peptidoglycan or murein</p> Signup and view all the answers

    Which of the following statements about peptidoglycan is incorrect?

    <p>The vertical layers are cross-linked by peptide bonds between identical amino acids.</p> Signup and view all the answers

    Which of the following statements about Gram-positive and Gram-negative bacteria is correct?

    <p>Gram-positive bacteria have a thicker peptidoglycan layer than Gram-negative bacteria.</p> Signup and view all the answers

    What is the function of the tetrapeptide attached to N-acetyl muramic acid (NAM) in the peptidoglycan layer?

    <p>It cross-links the vertical layers of peptidoglycan.</p> Signup and view all the answers

    What is the significance of the unique amino acids diaminopimelic acid and D-alanine in the peptidoglycan layer?

    <p>They are found exclusively in bacterial cell walls.</p> Signup and view all the answers

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