PHARM 321: IPFC - 6 Supportive Care with Cytotoxics

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10 Questions

What is the recommended preventive measure for radiation-induced mucositis according to MASCC guidelines?

Laser therapy

Which substance is thought to inhibit the production and effects of inflammatory cytokines in the context of mucositis prevention?

Benzydamine rinse

What is the effect of cryotherapy in reducing mucositis with 5-FU based regimens?

Leads to vasoconstriction

Which preventive measure is NOT recommended by MASCC guidelines for mucositis?

Chlorhexidine

How frequently is Benzydamine rinse administered for the prevention of radiation-induced mucositis?

q2-3h up to 8 times per day

What is the main difference between emesis and nausea in the context of chemotherapy-induced nausea and vomiting (CINV)?

Emesis is measured by the number of vomiting episodes, whereas nausea is the patient's perception of potentially vomiting

What is the key symptom of mucositis that distinguishes it from other conditions?

Ulceration of the lining of the mouth and throat

Which factor does NOT contribute to the risk of developing mucositis?

Intensive oral hygiene practices

What is a common complication associated with mucositis that makes it difficult for patients to perform basic functions?

Impaired ability to swallow solid food

Which category of emetic risk according to Hesketh Level has the lowest likelihood of causing vomiting?

Minimal (<5 episodes in 24 hours)

Learn about the management of chemotherapy induced nausea and vomiting (CINV) in the context of supportive care with cytotoxics. This lecture covers the incidence of CINV, factors influencing it, and strategies to address this worrisome adverse effect of chemotherapy.

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