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PHARM 321: IPFC - 6 Supportive Care with Cytotoxics

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PHARM 321: IPFC - 6 Supportive Care with Cytotoxics

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Questions and Answers

What is the recommended preventive measure for radiation-induced mucositis according to MASCC guidelines?

Laser therapy (correct)

Chlorhexidine

Sucralfate

Acyclovir

Which substance is thought to inhibit the production and effects of inflammatory cytokines in the context of mucositis prevention?

Palifermin

Benzydamine rinse (correct)

Elad S et al.

Antimicrobial lozenges

What is the effect of cryotherapy in reducing mucositis with 5-FU based regimens?

Reduces vasoconstriction

Leads to vasoconstriction (correct)

Increases the rate of mucositis

Enhances production of inflammatory cytokines

Which preventive measure is NOT recommended by MASCC guidelines for mucositis?

Chlorhexidine Signup and view all the answers

How frequently is Benzydamine rinse administered for the prevention of radiation-induced mucositis?

q2-3h up to 8 times per day Signup and view all the answers

What is the main difference between emesis and nausea in the context of chemotherapy-induced nausea and vomiting (CINV)?

Emesis is measured by the number of vomiting episodes, whereas nausea is the patient's perception of potentially vomiting Signup and view all the answers

What is the key symptom of mucositis that distinguishes it from other conditions?

Ulceration of the lining of the mouth and throat Signup and view all the answers

Which factor does NOT contribute to the risk of developing mucositis?

Intensive oral hygiene practices Signup and view all the answers

What is a common complication associated with mucositis that makes it difficult for patients to perform basic functions?

Impaired ability to swallow solid food Signup and view all the answers

Which category of emetic risk according to Hesketh Level has the lowest likelihood of causing vomiting?

Minimal (<5 episodes in 24 hours) Signup and view all the answers