PHAR 141G Pharmaceutics: Dosage Form Design Quiz

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What is the route of administration?

The brand name of the drug

The dosage of the drug

The frequency of drug intake

The path by which a drug is brought into contact with the body (correct)

What is the site of action?

The expiration date of a drug

The location where a drug exerts its effect in the body (correct)

The price of a drug

The place where a drug is manufactured

Which factor determines a drug's ultimate effectiveness?

Its taste

How well it passes through natural body barriers (correct)

Its packaging

Its color

What drives the absorption process in passive diffusion?

The concentration gradient of the drug across the membrane Signup and view all the answers

What differentiates local use from systemic use?

Whether the drug exerts its effect at a specific site or is absorbed into the blood Signup and view all the answers

What is the process by which a solid drug substance dissolves in a liquid to form a solution?

Dissolution Signup and view all the answers

Which of the following factors can affect the rate of dissolution of a drug?

All of the above Signup and view all the answers

What does bioavailability refer to?

The fraction of a drug that reaches the systemic circulation in its unchanged form after administration Signup and view all the answers

What does bioequivalence refer to?

The similarity in the rate and extent of drug absorption between two different formulations of the same drug Signup and view all the answers

What can affect the pharmacokinetics and pharmacodynamics of a drug?

The choice of dosage form Signup and view all the answers

What is an example of how different dosage forms can affect drug absorption?

A tablet may dissolve more slowly in the stomach compared to a liquid formulation, resulting in a delayed onset of action Signup and view all the answers

What is required for a drug to exhibit physical stability?

Retaining original properties like appearance and dissolution Signup and view all the answers

Which type of reaction is described as zero order?

The rate is independent of the concentration of the reactants Signup and view all the answers

What do excipients like antioxidants, preservatives, chelating agents, and buffering agents help in drug products?

Enhance physical stability Signup and view all the answers

In first-order reactions, what does the rate of reaction depend on?

Concentration of reactants Signup and view all the answers

Why are shelf life estimates necessary for drug products?

To help in setting appropriate expiration dates Signup and view all the answers

If an expiration date is provided for room temperature, what information would be needed to calculate the expiration extension if refrigerated?

% Decomposition at room temperature Signup and view all the answers

Which route of drug administration involves absorption through the skin for systemic action?

Transdermal Signup and view all the answers

What is a potential disadvantage of the transdermal route of drug administration?

May cause skin reactions Signup and view all the answers

Which route of drug administration is suitable for treating local diseases of the respiratory system while avoiding first-pass metabolism?

Oral inhalation Signup and view all the answers

What is a potential disadvantage of the oral inhalation route of drug administration?

Particle size determines drug deposition location Signup and view all the answers

Which route of drug administration is suitable for treating conditions of the ear?

Otic Signup and view all the answers

Which statement about the route of drug administration is correct?

The composition of the medicine is designed to enhance its absorption and metabolism. Signup and view all the answers

Which of the following best describes the term 'Biopharmaceutics'?

The study of how physical and chemical properties of a drug affect its absorption, distribution, metabolism, and excretion in the body Signup and view all the answers

What does the acronym 'ADME' stand for in the context of Pharmacokinetics?

Absorption, Distribution, Metabolism, and Excretion Signup and view all the answers

Which of the following best describes passive drug diffusion?

The process by which drugs move across cell membranes from an area of higher concentration to an area of lower concentration without the use of energy Signup and view all the answers

Which of the following factors does NOT affect the rate of dissolution of a drug?

Metabolic rate of the drug Signup and view all the answers

Which of the following best describes the term 'Pharmacokinetics'?

The study of how the body processes a drug, including its absorption, distribution, metabolism, and excretion Signup and view all the answers

Which of the following statements is TRUE about the relationship between different dosage forms and drug absorption?

Different dosage forms can result in different drug absorption rates and times of onset, peak, and duration of action Signup and view all the answers