PHAR 141G Pharmaceutics: Dosage Form Design Quiz
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Questions and Answers

What is the route of administration?

  • The brand name of the drug
  • The dosage of the drug
  • The frequency of drug intake
  • The path by which a drug is brought into contact with the body (correct)

    • What is the site of action?

  • The expiration date of a drug
  • The location where a drug exerts its effect in the body (correct)
  • The price of a drug
  • The place where a drug is manufactured

    • Which factor determines a drug's ultimate effectiveness?

  • Its taste
  • How well it passes through natural body barriers (correct)
  • Its packaging
  • Its color

    • What drives the absorption process in passive diffusion?

    <p>The concentration gradient of the drug across the membrane</p> Signup and view all the answers

    What differentiates local use from systemic use?

    <p>Whether the drug exerts its effect at a specific site or is absorbed into the blood</p> Signup and view all the answers

    What is the process by which a solid drug substance dissolves in a liquid to form a solution?

    <p>Dissolution</p> Signup and view all the answers

    Which of the following factors can affect the rate of dissolution of a drug?

    <p>All of the above</p> Signup and view all the answers

    What does bioavailability refer to?

    <p>The fraction of a drug that reaches the systemic circulation in its unchanged form after administration</p> Signup and view all the answers

    What does bioequivalence refer to?

    <p>The similarity in the rate and extent of drug absorption between two different formulations of the same drug</p> Signup and view all the answers

    What can affect the pharmacokinetics and pharmacodynamics of a drug?

    <p>The choice of dosage form</p> Signup and view all the answers

    What is an example of how different dosage forms can affect drug absorption?

    <p>A tablet may dissolve more slowly in the stomach compared to a liquid formulation, resulting in a delayed onset of action</p> Signup and view all the answers

    What is required for a drug to exhibit physical stability?

    <p>Retaining original properties like appearance and dissolution</p> Signup and view all the answers

    Which type of reaction is described as zero order?

    <p>The rate is independent of the concentration of the reactants</p> Signup and view all the answers

    What do excipients like antioxidants, preservatives, chelating agents, and buffering agents help in drug products?

    <p>Enhance physical stability</p> Signup and view all the answers

    In first-order reactions, what does the rate of reaction depend on?

    <p>Concentration of reactants</p> Signup and view all the answers

    Why are shelf life estimates necessary for drug products?

    <p>To help in setting appropriate expiration dates</p> Signup and view all the answers

    If an expiration date is provided for room temperature, what information would be needed to calculate the expiration extension if refrigerated?

    <p>% Decomposition at room temperature</p> Signup and view all the answers

    Which route of drug administration involves absorption through the skin for systemic action?

    <p>Transdermal</p> Signup and view all the answers

    What is a potential disadvantage of the transdermal route of drug administration?

    <p>May cause skin reactions</p> Signup and view all the answers

    Which route of drug administration is suitable for treating local diseases of the respiratory system while avoiding first-pass metabolism?

    <p>Oral inhalation</p> Signup and view all the answers

    What is a potential disadvantage of the oral inhalation route of drug administration?

    <p>Particle size determines drug deposition location</p> Signup and view all the answers

    Which route of drug administration is suitable for treating conditions of the ear?

    <p>Otic</p> Signup and view all the answers

    Which statement about the route of drug administration is correct?

    <p>The composition of the medicine is designed to enhance its absorption and metabolism.</p> Signup and view all the answers

    Which of the following best describes the term 'Biopharmaceutics'?

    <p>The study of how physical and chemical properties of a drug affect its absorption, distribution, metabolism, and excretion in the body</p> Signup and view all the answers

    What does the acronym 'ADME' stand for in the context of Pharmacokinetics?

    <p>Absorption, Distribution, Metabolism, and Excretion</p> Signup and view all the answers

    Which of the following best describes passive drug diffusion?

    <p>The process by which drugs move across cell membranes from an area of higher concentration to an area of lower concentration without the use of energy</p> Signup and view all the answers

    Which of the following factors does NOT affect the rate of dissolution of a drug?

    <p>Metabolic rate of the drug</p> Signup and view all the answers

    Which of the following best describes the term 'Pharmacokinetics'?

    <p>The study of how the body processes a drug, including its absorption, distribution, metabolism, and excretion</p> Signup and view all the answers

    Which of the following statements is TRUE about the relationship between different dosage forms and drug absorption?

    <p>Different dosage forms can result in different drug absorption rates and times of onset, peak, and duration of action</p> Signup and view all the answers

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