10 Questions
What are pessaries commonly used for?
Treatment of infection, vaginal atrophy, and for contraceptive purposes
How are pessaries formulated?
Using glycerol-gelatin or PEG bases
Why may the pH of pessaries be buffered to pH 4.5?
To enhance drug absorption
Which type of applicator is generally required for the administration of pessaries?
Specific applicator
In what situations might pessaries be used to achieve systemic absorption of therapeutic agents?
When local and systemic treatment are not effective
What is one benefit of using suppositories like misoprostol for inducing labor?
Ease of administration without need for water or equipment
Why do medications taken via suppository often reach peak blood concentration more quickly than oral dosage forms?
Absence of first pass metabolism in the liver
What precautions should be taken when handling suppositories to avoid complications?
Follow instructions carefully and wash hands before and after usage
Why is local application of suppositories beneficial in terms of duration of action?
It results in prolonged effect by providing sustained drug exposure
What potential side effect might some patients experience during the insertion of suppositories?
Burning or tearing of tissues
Test your knowledge on pessaries, which are vaginal suppositories used for treating infections, vaginal atrophy, contraception, and systemic absorption of therapeutic agents. Learn about their formulation using glycerol-gelatin or PEG bases and drug incorporation.
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