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Questions and Answers
Which of the following is NOT a major factor determining whether T cells are activated or tolerized?
Which of the following is NOT a major factor determining whether T cells are activated or tolerized?
- Regulatory T cells
- Cell-intrinsic anergy (correct)
- Antigen recognition
- Costimulation
What are the three major mechanisms of peripheral T cell tolerance?
What are the three major mechanisms of peripheral T cell tolerance?
- Antigen recognition, costimulation, and cell-intrinsic anergy
- Anergy, apoptosis, and costimulation (correct)
- Regulatory T cells, costimulation, and apoptosis
- Apoptosis, antigen recognition, and regulatory T cells
What is required for normal T cell responses?
What is required for normal T cell responses?
- Antigen recognition and apoptosis
- Antigen recognition and cell-intrinsic anergy
- Antigen recognition and costimulation (correct)
- Antigen recognition and regulatory T cells
Which of the following is a mechanism of peripheral tolerance for T cells?
Which of the following is a mechanism of peripheral tolerance for T cells?
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What is the role of costimulators in inducing T cell proliferation and differentiation?
What is the role of costimulators in inducing T cell proliferation and differentiation?
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Why do dendritic cells in normal uninfected tissues and peripheral lymphoid organs express little or no costimulators?
Why do dendritic cells in normal uninfected tissues and peripheral lymphoid organs express little or no costimulators?
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