Peripheral Neuropathy and Motor Units
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Questions and Answers

Which fibers are involved in the deficits described in the text?

  • Upper extremities
  • Lower extremities
  • Abdomen
  • All of the above (correct)

    • What is the most likely disease pathology based on the given information?

  • Demyelinating (correct)
  • Axonal
  • Cannot be determined
  • Mixed

    • Which of the following is NOT a potential cause of the peripheral neuropathy described?

  • Vasculitis (correct)
  • Acute polyneuropathy
  • Drug/toxin exposure
  • Inherited (developmental) neuropathy

    • Which treatment option is frequently preferred for ease of administration?

    <p>IVIG</p> Signup and view all the answers

    What percentage of patients usually recover completely?

    <p>80%</p> Signup and view all the answers

    What is the recommended medication for managing neuropathic pain in CIDP?

    <p>Gabapentin</p> Signup and view all the answers

    Which of the following is a potential cause of sensory neuropathy?

    <p>Vitamin B6 toxicity</p> Signup and view all the answers

    What is the key finding in demyelination?

    <p>Uniform demyelination</p> Signup and view all the answers

    What is the most common type of peripheral neuropathy?

    <p>Axonopathy</p> Signup and view all the answers

    What is the primary target of the immune attack in Guillain-Barre Syndrome?

    <p>Peripheral nerve myelin</p> Signup and view all the answers

    Which of the following is a potential cause of bilateral weakness in the hip flexors, quadriceps, and hamstrings?

    <p>Mononeuropathy</p> Signup and view all the answers

    What is the most likely disease pathology based on the given information?

    <p>Demyelinating</p> Signup and view all the answers

    What is the primary target of the immune attack in Guillain-Barre Syndrome?

    <p>Myelin sheath</p> Signup and view all the answers

    Which of the following is the recommended medication for managing neuropathic pain in CIDP?

    <p>Gabapentin</p> Signup and view all the answers

    What is the percentage of patients who usually recover completely from CIDP?

    <p>80%</p> Signup and view all the answers

    What is the recommended course of treatments for plasmapheresis in CIDP?

    <p>4-6 treatments over 810 days</p> Signup and view all the answers

    Which of the following is NOT a potential cause of Guillain-Barre syndrome?

    <p>Lead toxicity</p> Signup and view all the answers

    What is the most common type of peripheral neuropathy?

    <p>Axonal</p> Signup and view all the answers

    What is the primary target of the immune attack in Guillain-Barre syndrome?

    <p>Gangliosides/glycolipids</p> Signup and view all the answers

    What is the expected sensory loss in peripheral neuropathy?

    <p>Vibration and proprioception</p> Signup and view all the answers

    Which of the following is NOT a potential cause of peripheral neuropathy?

    <p>Guillain-Barre syndrome</p> Signup and view all the answers

    What is the primary target of the immune attack in Guillain-Barre syndrome?

    <p>Myelin sheath</p> Signup and view all the answers

    What is the most common type of peripheral neuropathy?

    <p>Polyneuropathy</p> Signup and view all the answers

    Which of the following is NOT a potential cause of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)?

    <p>Glucocorticoids</p> Signup and view all the answers

    What is the recommended medication for managing neuropathic pain in CIDP?

    <p>Gabapentin</p> Signup and view all the answers

    What is the expected percentage of patients who have a prolonged course with incomplete recovery from CIDP?

    <p>5-10%</p> Signup and view all the answers

    Which of the following is a potential cause of pure sensory/severe proprioceptive deficit in sensory neuropathy?

    <p>Vitamin B6 toxicity</p> Signup and view all the answers

    What is the most common type of peripheral neuropathy?

    <p>Axonal</p> Signup and view all the answers

    What is the etiology of peripheral neuropathy?

    <p>Inflammatory</p> Signup and view all the answers

    Is there an inherited (developmental) neuropathy?

    <p>Yes</p> Signup and view all the answers

    Which of the following is a potential cause of bilateral weakness in the hip flexors, quadriceps, and hamstrings?

    <p>Polyneuropathy</p> Signup and view all the answers

    What is the most likely disease pathology based on the given information?

    <p>Demyelinating</p> Signup and view all the answers

    What is the etiology of peripheral neuropathy?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is NOT a potential cause of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)?

    <p>Genetic mutation</p> Signup and view all the answers

    What is the expected percentage of patients who have a prolonged course with incomplete recovery from CIDP?

    <p>5-10%</p> Signup and view all the answers

    What is the percentage of patients who usually recover completely from CIDP?

    <p>70-80%</p> Signup and view all the answers

    Which of the following is NOT a potential cause of sensory neuropathy?

    <p>Diabetes</p> Signup and view all the answers

    What is the expected sensory loss in peripheral neuropathy?

    <p>Numbness and tingling in the feet and hands</p> Signup and view all the answers

    Which of the following is a potential cause of bilateral weakness in the hip flexors, quadriceps, and hamstrings?

    <p>Charcot-Marie-Tooth disease</p> Signup and view all the answers

    What is the most likely disease pathology based on the given information?

    <p>Axonal</p> Signup and view all the answers

    Which of the following is a potential cause of mononeuropathy?

    <p>Vasculitis</p> Signup and view all the answers

    What is the expected duration of most polyneuropathies?

    <p>Months to years</p> Signup and view all the answers

    Which of the following is a potential cause of sensory neuropathy?

    <p>Toxin exposure</p> Signup and view all the answers

    Which of the following is a potential cause of sensory neuropathy?

    <p>Amyloid</p> Signup and view all the answers

    What is the expected sensory loss in peripheral neuropathy?

    <p>Gradual onset of numbness</p> Signup and view all the answers

    What is the most likely disease pathology based on the given information?

    <p>Demyelinating</p> Signup and view all the answers

    What is the primary target of the immune attack in Guillain-Barre Syndrome?

    <p>Peripheral nerve myelin</p> Signup and view all the answers

    Which of the following is NOT a potential cause of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)?

    <p>Inherited (developmental) neuropathy</p> Signup and view all the answers

    What is the expected percentage of patients who have a prolonged course with incomplete recovery from CIDP?

    <p>5-10%</p> Signup and view all the answers

    Which treatment option is frequently preferred for ease of administration?

    <p>Intravenous immunoglobulin (IVIG)</p> Signup and view all the answers

    Which of the following is NOT a potential cause of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)?

    <p>Genetic mutation</p> Signup and view all the answers

    What is the expected sensory loss in peripheral neuropathy?

    <p>Loss of proprioception</p> Signup and view all the answers

    What is the recommended medication for managing neuropathic pain in CIDP?

    <p>Gabapentin</p> Signup and view all the answers

    Which of the following is a potential cause of Guillain-Barre syndrome?

    <p>Carcinoma (paraneoplastic)</p> Signup and view all the answers

    What is the primary target of the immune attack in Guillain-Barre Syndrome?

    <p>Gangliosides/glycolipids</p> Signup and view all the answers

    What is the most common type of peripheral neuropathy?

    <p>Axonal neuropathy</p> Signup and view all the answers

    What is the expected percentage of patients who usually recover completely from CIDP?

    <p>30-40%</p> Signup and view all the answers

    Which of the following is NOT a potential cause of mononeuropathy?

    <p>Guillain-Barre syndrome</p> Signup and view all the answers

    What is the expected duration of most polyneuropathies?

    <p>Months to years</p> Signup and view all the answers

    Which of the following is a potential cause of symmetric polyneuropathy?

    <p>Mononeuropathy</p> Signup and view all the answers

    Which of the following is NOT a potential cause of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)?

    <p>Genetic mutation</p> Signup and view all the answers

    What is the expected percentage of patients who have a prolonged course with incomplete recovery from CIDP?

    <p>10%</p> Signup and view all the answers

    What is the recommended medication for managing neuropathic pain in CIDP?

    <p>Gabapentin</p> Signup and view all the answers

    Which of the following is a potential cause of acute polyneuropathy?

    <p>Guillain-Barre syndrome</p> Signup and view all the answers

    Which of the following is a potential cause of mononeuropathy?

    <p>Vasculitis</p> Signup and view all the answers

    Which of the following is a potential cause of symmetric polyneuropathy?

    <p>CIDP</p> Signup and view all the answers

    Which of the following is NOT a potential cause of peripheral neuropathy?

    <p>Lead toxicity</p> Signup and view all the answers

    What is the expected sensory loss in peripheral neuropathy?

    <p>Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms.</p> Signup and view all the answers

    What is the primary target of the immune attack in Guillain-Barre syndrome?

    <p>Peripheral nerve myelin</p> Signup and view all the answers

    What is the most common type of peripheral neuropathy?

    <p>Axonal neuropathy</p> Signup and view all the answers

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