Perioperative Fluid and Blood Management Quiz
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Questions and Answers

What are some physical exam indications of hypovolemia?

abnormal skin turgor, dehydrated mucous membranes, thready peripheral pulses, increased resting HR, BP changes from supine to sitting or standing (orthostatic changes), decreased urinary flow rate

What are some physical exam indications of hypervolemia?

pretibial pitting edema in the ambulatory patient, presacral pitting edema in the bedridden patient, late signs of hypervolemia: CHF, tachycardia, tachypnea, elevated jugular pulse pressure, pulmonary crackles, wheezing, cyanosis, pink and frothy pulmonary secretions

What are some laboratory evaluation signs of dehydration?

rising hematocrit and hemoglobin, progressive metabolic acidosis (including lactic acidosis), urine specific gravity > 1

What are some surrogate measures of intravascular volume in laboratory evaluation?

<p>serial hematocrit, arterial blood pH, urine specific gravity or osmolality, urine serum sodium or chloride concentration, serum sodium, BUN-to-creatinine ratio</p> Signup and view all the answers

What are some indirect measures of intravascular volume in laboratory evaluation?

<p>may be altered by perioperative factors</p> Signup and view all the answers

What are some lab signs of dehydration?

<p>rising hematocrit and hemoglobin, progressive metabolic acidosis (including lactic acidosis), urine specific gravity &gt; 1</p> Signup and view all the answers

  1. What are the three functions of crossmatching in blood transfusion?

<p>The three functions of crossmatching in blood transfusion are to confirm ABO and Rh typing, to detect antibodies to other blood group systems, and to detect antibodies in low titers or those that do not agglutinate easily.</p> Signup and view all the answers

  1. What are some complications of massive blood transfusion?

<p>Some complications of massive blood transfusion include coagulopathy (dilutional thrombocytopenia, lack of factors 5 &amp; 8, DIC), and metabolic problems (hyperkalemia, citrate toxicity, acidosis, hypothermia, impaired O2 carrying capacity due to reduced 2,3 DPG concentration).</p> Signup and view all the answers

  1. By how much will transfusing one unit of PRBCs increase the hematocrit in an average adult?

<p>Transfusing one unit of PRBCs will increase the hematocrit by 2-3% or 1 g/dL of Hgb in an average adult.</p> Signup and view all the answers

  1. What are the clinical manifestations of a hemolytic blood transfusion reaction?

<p>The clinical manifestations of a hemolytic blood transfusion reaction include fever, chills, chest/flank/back pain, nausea, oliguria or anuria, hemoglobinuria, diffuse bleeding, and indicators of decreased temperature, blood pressure, and urine output if the patient is asleep.</p> Signup and view all the answers

  1. What are the alternatives to homologous blood transfusion?

<p>The alternatives to homologous blood transfusion include autologous transfusion, perioperative blood salvage (CellSaver), intraoperative hemodilution, and the use of substitute products.</p> Signup and view all the answers

  1. What are the indications for Fresh Frozen Plasma (FFP) administration?

<p>The indications for Fresh Frozen Plasma (FFP) administration include treatment of isolated factor deficiencies, reversal of warfarin, and correction of coagulopathy associated with liver disease. 1 unit of FFP increases the level of clotting by 2-3% in adults.</p> Signup and view all the answers

Explain the significance of pulmonary artery occlusion pressure (PAOP) measurements in fluid management.

<p>PAOP measurements help determine a patient's volume status. A PAOP &lt; 8 mmHg indicates hypovolemia in patients with normal LV compliance, while PAOP &lt; 15 mmHg indicates relative hypovolemia in patients with impaired LV compliance.</p> Signup and view all the answers

Compare the accuracy of echocardiography and pulmonary artery pressure measurements in determining cardiac filling pressures.

<p>Echocardiography is more accurate at determining cardiac filling pressures than PA pressure measurements.</p> Signup and view all the answers

Discuss the impact of ventilation on blood pressure.

<p>During spontaneous ventilation, blood pressure decreases on inspiration, while during positive pressure ventilation, it increases on inspiration.</p> Signup and view all the answers

Distinguish between the characteristics and roles of crystalloid and colloid solutions in fluid management.

<p>Crystalloid solutions rapidly equilibrate with and distribute throughout the entire extracellular fluid space, while colloid solutions help maintain plasma colloid oncotic pressure and mostly remain intravascular.</p> Signup and view all the answers

Explain the differences in intravascular half-life between crystalloid and colloid solutions.

<p>The intravascular half-life of crystalloid solutions is 20-30 minutes, while for colloid solutions, it is 3-6 hours.</p> Signup and view all the answers

What are the indications for using colloids in fluid resuscitation?

<p>Colloids are indicated for fluid resuscitation in severe intravascular fluid deficits (e.g., hemorrhagic shock) prior to the arrival of blood for transfusion.</p> Signup and view all the answers

Explain the determinants of perioperative fluid requirements.

<p>The determinants of perioperative fluid requirements include basal requirements, preoperative deficits, blood loss, third space losses, evaporation losses, transcellular fluid losses, effects of anesthesia, and urine output.</p> Signup and view all the answers

What are the normal hemoglobin (Hgb) levels for males and females?

<p>Normal hemoglobin (Hgb) levels are 14-18 g/dl for males and 12-16 g/dl for females.</p> Signup and view all the answers

Describe the physiologic adaptations to acute normovolemic anemia during surgery.

<p>Physiologic adaptations to acute normovolemic anemia during surgery include increased cardiac output, redistribution of blood to oxygen-dependent tissues, and increased oxygen extraction.</p> Signup and view all the answers

What are the acceptable minimum preoperative hematocrit levels for healthy patients and those with symptomatic cardiac disease?

<p>An acceptable minimum preoperative hematocrit for healthy patients is 18%, while patients with symptomatic cardiac disease should have a preoperative hematocrit of 30%.</p> Signup and view all the answers

What are the different types of red cell products available?

<p>Red cell products available include red blood cells, deglycerolized red blood cells, leukocyte-reduced red blood cells, washed red blood cells, and whole blood.</p> Signup and view all the answers

What is the difference between a type and screen and a crossmatch?

<p>The difference between a type and screen and a crossmatch is that the former identifies the patient's blood type and screens for antibodies, while the latter tests compatibility between donor and recipient blood.</p> Signup and view all the answers

Describe the dangers of increased interstitial fluid in perioperative fluid management.

<p>Potential dangers include pulmonary edema, acidosis, and hindered healing due to the increased interstitial fluid.</p> Signup and view all the answers

What are the determinants of fluid requirements in perioperative fluid management?

<p>Fluid requirements are determined by preoperative loss replacement, maintenance fluid replacement, surgical loss replacement, and blood loss replacement.</p> Signup and view all the answers

How is the daily fluid requirement calculated in perioperative fluid management?

<p>The daily fluid requirement is calculated based on a 4-2-1 rule and adjusted for metabolic rate.</p> Signup and view all the answers

What is goal-directed fluid therapy and how does it guide fluid administration in perioperative fluid management?

<p>Goal-directed fluid therapy utilizes stroke volume and cardiac output to guide fluid administration in perioperative fluid management.</p> Signup and view all the answers

What is the preferred initial resuscitation fluid in perioperative fluid management, and how does it distribute in the body?

<p>Balanced salt solution is the preferred initial resuscitation fluid, distributing quickly into both blood volume and interstitial fluid.</p> Signup and view all the answers

What are third-space losses and how are they managed in perioperative fluid management?

<p>Third-space losses refer to unexplained fluid requirements, necessitating further infusions to maintain intravascular volume and adequate perfusion.</p> Signup and view all the answers

Study Notes

Perioperative Fluid Management

  • Pulmonary edema, acidosis, and hindered healing are dangers of increased interstitial fluid
  • UOP and blood pressure are not reliable indicators of fluid status
  • Fluid requirements are determined by preoperative loss replacement, maintenance fluid replacement, surgical loss replacement, and blood loss replacement
  • Daily fluid requirement is calculated based on a 4-2-1 rule and adjusted for metabolic rate
  • Goal-directed fluid therapy utilizes stroke volume and cardiac output to guide fluid administration
  • Anticipated surgical fluid loss varies based on the extent of tissue trauma
  • Proper preoperative evaluation of volume status involves a thorough history, physical assessment, vital signs, urine output, and laboratory determinations
  • Signs and symptoms of un-replaced acute blood loss progress from thirst and vasoconstriction to coma and near death
  • Resuscitation goals for hypovolemic patients include restoration of microcirculation and reversal of hypovolemia
  • Balanced salt solution is the preferred initial resuscitation fluid, distributing quickly into both blood volume and interstitial fluid
  • Third-space losses refer to unexplained fluid requirements, necessitating further infusions to maintain intravascular volume and adequate perfusion
  • Internal losses, such as those from major intra-abdominal procedures, can lead to temporary sequestration of fluid into a non-functional third space

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Test your knowledge of perioperative fluid management with this quiz. Explore topics such as fluid requirements, goal-directed fluid therapy, preoperative evaluation, resuscitation goals, and types of fluid losses.

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